Toward more accurate data in cardiac cellular electrophysiology

j 2020

Toward more accurate data in cardiac cellular electrophysiology

BÉBAROVÁ, Markéta, Michal PÁSEK a Ivan ZAHRADNIK

Základní údaje

Originální název

Toward more accurate data in cardiac cellular electrophysiology

Autoři

BÉBAROVÁ, Markéta, Michal PÁSEK a Ivan ZAHRADNIK

Vydání

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, OXFORD, PERGAMON-ELSEVIER SCIENCE LTD, 2020, 0079-6107

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku (nerecenzovaný)

Obor

10608 Biochemistry and molecular biology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.667

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.pbiomolbio.2020.06.006

UT WoS

000582745400001

Klíčová slova anglicky

cardiac cellular electrophysiology

Příznaky

Mezinárodní význam

Změněno: 8. 4. 2021 08:52, Mgr. Tereza Miškechová

Anotace

V originále

The divergence of published data is a well-recognised problem of experimental sciences including cardiac cellular electrophysiology. Differences in experimental conditions as well as in experimental models are commonly known to be potential reasons for this. Properties of individual cardiac myocytes vary depending on their localisation in the heart muscle, but also differ among species and strains, age and gender groups, housing and health conditions, to name the most often discussed sources of variability. However, limits of accuracy of experimental data arising from sub-optimal measurement and evaluation methods represent another important and often neglected source of data inconsistency. The term accuracy stands often for both the closeness of measured values to the true value of a parameter and the closeness of individual measurements to each other (the latter is also called precision). Both these aspects of accuracy are indeed essential to obtain data as close to reality as possible. This Special Issue is therefore aimed to address methodological factors that should be considered to minimize variability and inconsistency, or in other words, to maximize reproducibility of electrophysiological studies.

Citovat

BÉBAROVÁ, Markéta, Michal PÁSEK a Ivan ZAHRADNIK. Toward more accurate data in cardiac cellular electrophysiology. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2020, roč. 157, NOV 2020, s. 1-2. ISSN 0079-6107. Dostupné z: https://dx.doi.org/10.1016/j.pbiomolbio.2020.06.006.

@article{1692059,
   author = {Bébarová, Markéta and Pásek, Michal and Zahradnik, Ivan},
   article_location = {OXFORD},
   article_number = {NOV 2020},
   doi = {http://dx.doi.org/10.1016/j.pbiomolbio.2020.06.006},
   keywords = {cardiac cellular electrophysiology},
   language = {eng},
   issn = {0079-6107},
   journal = {PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY},
   note = {Editorial.},
   title = {Toward more accurate data in cardiac cellular electrophysiology},
   url = {https://www.sciencedirect.com/science/article/pii/S0079610720300638?via%3Dihub},
   volume = {157},
   year = {2020}
}

TY  - JFULL
ID  - 1692059
AU  - Bébarová, Markéta - Pásek, Michal - Zahradnik, Ivan
PY  - 2020
TI  - Toward more accurate data in cardiac cellular electrophysiology
JF  - PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
VL  - 157
IS  - NOV 2020
SP  - 1-2
EP  - 1-2
PB  - PERGAMON-ELSEVIER SCIENCE LTD
SN  - 00796107
N1  - Editorial.
KW  - cardiac cellular electrophysiology
UR  - https://www.sciencedirect.com/science/article/pii/S0079610720300638?via%3Dihub
L2  - https://www.sciencedirect.com/science/article/pii/S0079610720300638?via%3Dihub
N2  - The divergence of published data is a well-recognised problem of experimental sciences including cardiac cellular electrophysiology. Differences in experimental conditions as well as in experimental models are commonly known to be potential reasons for this. Properties of individual cardiac myocytes vary depending on their localisation in the heart muscle, but also differ among species and strains, age and gender groups, housing and health conditions, to name the most often discussed sources of variability. However, limits of accuracy of experimental data arising from sub-optimal measurement and evaluation methods represent another important and often neglected source of data inconsistency. The term accuracy stands often for both the closeness of measured values to the true value of a parameter and the closeness of individual measurements to each other (the latter is also called precision). Both these aspects of accuracy are indeed essential to obtain data as close to reality as possible. This Special Issue is therefore aimed to address methodological factors that should be considered to minimize variability and inconsistency, or in other words, to maximize reproducibility of electrophysiological studies.
ER  -

BÉBAROVÁ, Markéta, Michal PÁSEK a Ivan ZAHRADNIK. Toward more accurate data in cardiac cellular electrophysiology. \textit{PROGRESS IN BIOPHYSICS \&{}amp; MOLECULAR BIOLOGY}. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2020, roč.~157, NOV 2020, s.~1-2. ISSN~0079-6107. Dostupné z: https://dx.doi.org/10.1016/j.pbiomolbio.2020.06.006.

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