Failure properties of abdominal aortic aneurysm tissue are
orientation dependent

J 2021

Failure properties of abdominal aortic aneurysm tissue are orientation dependent

POLZER, Stanislav, Vojtěch MAN, Robert VLACHOVSKÝ, Luboš KUBÍČEK, Jan KRACÍK et. al.

Základní údaje

Originální název

Failure properties of abdominal aortic aneurysm tissue are orientation dependent

Autoři

POLZER, Stanislav (203 Česká republika, garant), Vojtěch MAN (203 Česká republika), Robert VLACHOVSKÝ (203 Česká republika, domácí), Luboš KUBÍČEK (203 Česká republika, domácí), Jan KRACÍK (203 Česká republika), Robert STAFFA (203 Česká republika, domácí), Tomáš NOVOTNÝ (203 Česká republika, domácí), Jiří BURŠA (203 Česká republika) a M.L. RAGHAVAN (840 Spojené státy)

Vydání

Journal of the Mechanical Behavior of Biomedical Materials, Elsevier, Amsterdam, 2021, 1751-6161

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

20901 Industrial biotechnology

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.042

Kód RIV

RIV/00216224:14110/21:00120077

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.jmbbm.2020.104181

UT WoS

000608182400007

Klíčová slova anglicky

Abdominal aortic aneurysm; Failure properties; Mechanical testing; Sample orientation

Štítky

14110121, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 2. 2021 12:35, Mgr. Tereza Miškechová

Anotace

V originále

Introduction: Biomechanical rupture risk assessment of abdominal aortic aneurysm (AAA) requires information about failure properties of aneurysmal tissue. There are large differences between reported values. Among others, studies vary in using either axially or circumferentially oriented samples. This study investigates the effect of sample orientation on failure properties. Methods: Aneurysmal tissues from 45 patients (11 females) were harvested during open AAA repair, cut into uniaxial samples (90) and tested mechanically within 3 h. If possible, the samples were cut in both axial (49 samples) and circumferential (41 samples) directions. Wall thickness, First Piola-Kirchhoff strength P-ult and ultimate tension T-ult were recorded. Influence of sample orientation and other clinical parameters were investigated using non parametric tests. Results: Medians of Pull (values 1100 kPa for circumferential vs. 715 kPa for axial direction, p < 10(-4)) and T-ult (17.4 N/cm in circumferential vs. 11.2 N/cm in axial direction, p < 10(-4)) were significantly higher in circumferential direction. For paired data, the median of difference was 411 kPa (p < 10(-3)) in P-ult, and 7.4 N/cm < 10(-4)) in T-ult in favor of circumferential direction. Conclusions: In this first study of anisotropy in AAA wall failure properties using paired comparisons, the strength in circumferential orientation was found to be higher than in axial orientation.

Návaznosti

NV17-29701A, projekt VaV

Název: Ischémií modifikovaný albumin a cirkulující mikroRNA jako nové technologie k monitorování tkáňové ischémie po cévních rekonstrukcích na břišní aortě

Citovat

POLZER, Stanislav, Vojtěch MAN, Robert VLACHOVSKÝ, Luboš KUBÍČEK, Jan KRACÍK, Robert STAFFA, Tomáš NOVOTNÝ, Jiří BURŠA a M.L. RAGHAVAN. Failure properties of abdominal aortic aneurysm tissue are orientation dependent. Journal of the Mechanical Behavior of Biomedical Materials. Elsevier: Amsterdam, 2021, roč. 114, FEB 2021, s. 1-7. ISSN 1751-6161. Dostupné z: https://dx.doi.org/10.1016/j.jmbbm.2020.104181.

@article{1698685,
   author = {Polzer, Stanislav and Man, Vojtěch and Vlachovský, Robert and Kubíček, Luboš and Kracík, Jan and Staffa, Robert and Novotný, Tomáš and Burša, Jiří and Raghavan, M.L.},
   article_location = {Elsevier},
   article_number = {FEB 2021},
   doi = {http://dx.doi.org/10.1016/j.jmbbm.2020.104181},
   keywords = {Abdominal aortic aneurysm; Failure properties; Mechanical testing; Sample orientation},
   language = {eng},
   issn = {1751-6161},
   journal = {Journal of the Mechanical Behavior of Biomedical Materials},
   title = {Failure properties of abdominal aortic aneurysm tissue are orientation dependent},
   url = {https://www.sciencedirect.com/science/article/pii/S1751616120307232?via%3Dihub},
   volume = {114},
   year = {2021}
}

TY  - JOUR
ID  - 1698685
AU  - Polzer, Stanislav - Man, Vojtěch - Vlachovský, Robert - Kubíček, Luboš - Kracík, Jan - Staffa, Robert - Novotný, Tomáš - Burša, Jiří - Raghavan, M.L.
PY  - 2021
TI  - Failure properties of abdominal aortic aneurysm tissue are orientation dependent
JF  - Journal of the Mechanical Behavior of Biomedical Materials
VL  - 114
IS  - FEB 2021
SP  - 1-7
EP  - 1-7
PB  - Amsterdam
SN  - 17516161
KW  - Abdominal aortic aneurysm
KW  - Failure properties
KW  - Mechanical testing
KW  - Sample orientation
UR  - https://www.sciencedirect.com/science/article/pii/S1751616120307232?via%3Dihub
L2  - https://www.sciencedirect.com/science/article/pii/S1751616120307232?via%3Dihub
N2  - Introduction: Biomechanical rupture risk assessment of abdominal aortic aneurysm (AAA) requires information about failure properties of aneurysmal tissue. There are large differences between reported values. Among others, studies vary in using either axially or circumferentially oriented samples. This study investigates the effect of sample orientation on failure properties. Methods: Aneurysmal tissues from 45 patients (11 females) were harvested during open AAA repair, cut into uniaxial samples (90) and tested mechanically within 3 h. If possible, the samples were cut in both axial (49 samples) and circumferential (41 samples) directions. Wall thickness, First Piola-Kirchhoff strength P-ult and ultimate tension T-ult were recorded. Influence of sample orientation and other clinical parameters were investigated using non parametric tests. Results: Medians of Pull (values 1100 kPa for circumferential vs. 715 kPa for axial direction, p < 10(-4)) and T-ult (17.4 N/cm in circumferential vs. 11.2 N/cm in axial direction, p < 10(-4)) were significantly higher in circumferential direction. For paired data, the median of difference was 411 kPa (p < 10(-3)) in P-ult, and 7.4 N/cm < 10(-4)) in T-ult in favor of circumferential direction. Conclusions: In this first study of anisotropy in AAA wall failure properties using paired comparisons, the strength in circumferential orientation was found to be higher than in axial orientation.
ER  -

POLZER, Stanislav, Vojtěch MAN, Robert VLACHOVSKÝ, Luboš KUBÍČEK, Jan KRACÍK, Robert STAFFA, Tomáš NOVOTNÝ, Jiří BURŠA a M.L. RAGHAVAN. Failure properties of abdominal aortic aneurysm tissue are orientation dependent. \textit{Journal of the Mechanical Behavior of Biomedical Materials}. Elsevier: Amsterdam, 2021, roč.~114, FEB 2021, s.~1-7. ISSN~1751-6161. Dostupné z: https://dx.doi.org/10.1016/j.jmbbm.2020.104181.

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