Detailed Information on Publication Record
2020
A play on cilia beating
ČAJÁNEK, LukášBasic information
Original name
A play on cilia beating
Authors
ČAJÁNEK, Lukáš (203 Czech Republic, guarantor, belonging to the institution)
Edition
Journal of Biological Chemistry, Bethesda, USA, Amer. Soc. Biochem. Mol. Biol. 2020, 0021-9258
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10608 Biochemistry and molecular biology
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 5.157
RIV identification code
RIV/00216224:14110/20:00114499
Organization unit
Faculty of Medicine
UT WoS
000586428700002
Keywords in English
cilia beating
Tags
Tags
International impact, Reviewed
Změněno: 24/11/2020 10:21, Mgr. Tereza Miškechová
Abstract
V originále
Motile cilia, hairlike structures present on the cell surface, have a well-appreciated role in human physiology, including sweeping mucus, dirt and debris out of the respiratory tract. However, we are only beginning to understand the mechanisms governing cilia growth, maintenance and function. In this issue, Arora et al. reveal new details about the control of cilia growth. They identify a previously unrecognized connection between adenylate cyclase 6 (AC6), a cilia signaling mediator, and the autophagy-mediated regulation of motile cilia length via kinesin Kif19a, a regulator of cilia length. These findings provide new insights into motile cilia biology and may lead to novel ciliopathy treatments.
Links
| GA19-05244S, research and development project |
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