Echocardiographic signs of subclinical cardiac function
impairment in Duchenne dystrophy gene carriers

J 2020

Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers

KINCL, Vladimír, Roman PANOVSKÝ, Martin PEŠL, Jan MÁCHAL, Lenka JUŘÍKOVÁ et. al.

Základní údaje

Originální název

Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers

Autoři

KINCL, Vladimír (203 Česká republika, garant, domácí), Roman PANOVSKÝ (203 Česká republika, domácí), Martin PEŠL (203 Česká republika, domácí), Jan MÁCHAL (203 Česká republika, domácí), Lenka JUŘÍKOVÁ (203 Česká republika, domácí), Jana HABERLOVÁ (203 Česká republika) a Lucia MASÁROVÁ (703 Slovensko, domácí)

Vydání

Scientific Reports, Berlin, Nature, 2020, 2045-2322

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.379

Kód RIV

RIV/00216224:14110/20:00117280

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1038/s41598-020-77882-6

UT WoS

000596311900004

Klíčová slova anglicky

Duchenne dystrophy; subclinical cardiac function impairment

Štítky

14110115, 14110320, 14110513, 14110518, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 12. 5. 2021 14:20, Mgr. Tereza Miškechová

Anotace

V originále

To assess subclinical cardiac function impairment in Duchenne dystrophy (DMD) female carriers. Forty-four female subjects proved as DMD carriers underwent echocardiographic examination including tissue Doppler imaging (TDI) of mitral and tricuspid annulus. Seventeen age-matched healthy female subjects served as controls. A significant differences in peak systolic annular velocity (Sa) between carriers and controls were found for lateral and septal part of the mitral annulus and for tricuspid annulus (0.09 vs. 0.11 m/s, p<0.001, 0.08 vs. 0.09 m/s, p<0.01 and 0.13 vs. 0.14 m/s, p=0.02 respectively). There was also difference in early diastolic velocity (Ea) of the septal part of the mitral annulus (0.11 vs. 0.13 m/s, p=0.03). The subclinical deterioration of systolic function is presented even in asymptomatic DMD female carriers.

Návaznosti

MUNI/A/1493/2018, interní kód MU

Název: Hodnocení funkce levé komory s využitím metody feature tracking u nosiček genů pro Duchennovu muskulární dystrofii (Akronym: CMRDMD)

Investor: Masarykova univerzita, Hodnocení funkce levé komory s využitím metody feature tracking u nosiček genů pro Duchennovu muskulární dystrofii, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

KINCL, Vladimír, Roman PANOVSKÝ, Martin PEŠL, Jan MÁCHAL, Lenka JUŘÍKOVÁ, Jana HABERLOVÁ a Lucia MASÁROVÁ. Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers. Scientific Reports. Berlin: Nature, 2020, roč. 10, č. 1, s. 1-6. ISSN 2045-2322. Dostupné z: https://dx.doi.org/10.1038/s41598-020-77882-6.

@article{1706276,
   author = {Kincl, Vladimír and Panovský, Roman and Pešl, Martin and Máchal, Jan and Juříková, Lenka and Haberlová, Jana and Masárová, Lucia},
   article_location = {Berlin},
   article_number = {1},
   doi = {http://dx.doi.org/10.1038/s41598-020-77882-6},
   keywords = {Duchenne dystrophy; subclinical cardiac function impairment},
   language = {eng},
   issn = {2045-2322},
   journal = {Scientific Reports},
   title = {Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers},
   url = {https://www.nature.com/articles/s41598-020-77882-6.pdf},
   volume = {10},
   year = {2020}
}

TY  - JOUR
ID  - 1706276
AU  - Kincl, Vladimír - Panovský, Roman - Pešl, Martin - Máchal, Jan - Juříková, Lenka - Haberlová, Jana - Masárová, Lucia
PY  - 2020
TI  - Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers
JF  - Scientific Reports
VL  - 10
IS  - 1
SP  - 1-6
EP  - 1-6
PB  - Nature
SN  - 20452322
KW  - Duchenne dystrophy
KW  - subclinical cardiac function impairment
UR  - https://www.nature.com/articles/s41598-020-77882-6.pdf
L2  - https://www.nature.com/articles/s41598-020-77882-6.pdf
N2  - To assess subclinical cardiac function impairment in Duchenne dystrophy (DMD) female carriers. Forty-four female subjects proved as DMD carriers underwent echocardiographic examination including tissue Doppler imaging (TDI) of mitral and tricuspid annulus. Seventeen age-matched healthy female subjects served as controls. A significant differences in peak systolic annular velocity (Sa) between carriers and controls were found for lateral and septal part of the mitral annulus and for tricuspid annulus (0.09 vs. 0.11 m/s, p<0.001, 0.08 vs. 0.09 m/s, p<0.01 and 0.13 vs. 0.14 m/s, p=0.02 respectively). There was also difference in early diastolic velocity (Ea) of the septal part of the mitral annulus (0.11 vs. 0.13 m/s, p=0.03). The subclinical deterioration of systolic function is presented even in asymptomatic DMD female carriers.
ER  -

KINCL, Vladimír, Roman PANOVSKÝ, Martin PEŠL, Jan MÁCHAL, Lenka JUŘÍKOVÁ, Jana HABERLOVÁ a Lucia MASÁROVÁ. Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers. \textit{Scientific Reports}. Berlin: Nature, 2020, roč.~10, č.~1, s.~1-6. ISSN~2045-2322. Dostupné z: https://dx.doi.org/10.1038/s41598-020-77882-6.

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