SALMANTON-GARCIA, Jon, Philipp KOEHLER, Anupma KINDO, Iker FALCES-ROMERO, Julio GARCIA-RODRIGUEZ, Zdeněk RÁČIL, Sharon C. A. CHEN, Nikolai KLIMKO, Guillaume DESOUBEAUX, George R. THOMPSON, Miguel-Angel BENITEZ-PENUELA, Jose-Yesid RODRIGUEZ, Donald C. SHEPPARD, Martin HOENIGL, Yohann LE GOVIC, Hamid BADALI, John W. BADDLEY, Jagdish CHANDER, Paul R. INGRAM, Diana L. PAKSTIS, Sibylle C. MELLINGHOFF, Serkan ATICI, Simone CESARO, Arunaloke CHAKRABARTI, Damien DUPONT, Gloria M. GONZALEZ, Lorant HATVANI, Raoul HERBRECHT, Galina KLYASOVA, Cornelia LASS-FLORL, Mihai MARES, Kathleen MULLANE, Donald C. VINH, Hilmar WISPLINGHOFF, Michaela LACKNER, Oliver A. CORNELY a Danila SEIDEL. Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScope (R)-Global Registry for Emerging Fungal Infections. The Journal of infection. London: Academic Press, 2020, roč. 81, č. 5, s. 802-815. ISSN 0163-4453. Dostupné z: https://dx.doi.org/10.1016/j.jinf.2020.08.015.
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Základní údaje
Originální název Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScope (R)-Global Registry for Emerging Fungal Infections
Autoři SALMANTON-GARCIA, Jon, Philipp KOEHLER, Anupma KINDO, Iker FALCES-ROMERO, Julio GARCIA-RODRIGUEZ, Zdeněk RÁČIL (203 Česká republika, domácí), Sharon C. A. CHEN, Nikolai KLIMKO, Guillaume DESOUBEAUX, George R. THOMPSON, Miguel-Angel BENITEZ-PENUELA, Jose-Yesid RODRIGUEZ, Donald C. SHEPPARD, Martin HOENIGL, Yohann LE GOVIC, Hamid BADALI, John W. BADDLEY, Jagdish CHANDER, Paul R. INGRAM, Diana L. PAKSTIS, Sibylle C. MELLINGHOFF, Serkan ATICI, Simone CESARO, Arunaloke CHAKRABARTI, Damien DUPONT, Gloria M. GONZALEZ, Lorant HATVANI, Raoul HERBRECHT, Galina KLYASOVA, Cornelia LASS-FLORL, Mihai MARES, Kathleen MULLANE, Donald C. VINH, Hilmar WISPLINGHOFF, Michaela LACKNER, Oliver A. CORNELY a Danila SEIDEL.
Vydání The Journal of infection, London, Academic Press, 2020, 0163-4453.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30303 Infectious Diseases
Stát vydavatele Švýcarsko
Utajení není předmětem státního či obchodního tajemství
WWW URL
Impakt faktor Impact factor: 6.072
Kód RIV RIV/00216224:14110/20:00117464
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.1016/j.jinf.2020.08.015
UT WoS 000586323400017
Klíčová slova anglicky Rare; Invasive fungal infections; Registry; Mold; Yeast
Štítky 14110212, rivok
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Mgr. Tereza Miškechová, učo 341652. Změněno: 21. 12. 2020 09:26.
Anotace
Objectives: Emerging invasive fungal infections (IFI) have become a notable challenge. Apart from the more frequently described fusariosis, lomentosporiosis, mucormycosis, scedosporiosis, and certain dematiaceae or yeasts, little is known about extremely rare IFI. Methods: Extremely rare IFI collected in the FungiScope (R) registry were grouped as Dematiaceae, Hypocreales, Saccharomycetales, Eurotiales, Dermatomycetes, Agaricales, and Mucorales. Results: Between 2003 and June 2019, 186 extremely rare IFI were documented in FungiScope (R). Dematiaceae (35.5%), Hypocreales (23.1%), Mucorales (11.8%), and Saccharomycetales (11.3%) caused most IFI. Most patients had an underlying malignancy (38.7%) with acute leukemia accounting for 50% of cancers. Dissemination was observed in 26.9% of the patients. Complete or partial clinical response rate was 68.3%, being highest in Eurotiales (82.4%) and in Agaricales (80.0%). Overall mortality rate was 29.3%, ranging from 11.8% in Eurotiales to 50.0% in Mucorales. Conclusions: Physicians are confronted with a complex variety of fungal pathogens, for which treatment recommendations are lacking and successful outcome might be incidental. Through an international consortium of physicians and scientists, these cases of extremely rare IFI can be collected to further investigate their epidemiology and eventually identify effective treatment regimens. (C) 2020 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
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