SALMANTON-GARCIA, Jon, Philipp KOEHLER, Anupma KINDO, Iker FALCES-ROMERO, Julio GARCIA-RODRIGUEZ, Zdeněk RÁČIL, Sharon C. A. CHEN, Nikolai KLIMKO, Guillaume DESOUBEAUX, George R. THOMPSON, Miguel-Angel BENITEZ-PENUELA, Jose-Yesid RODRIGUEZ, Donald C. SHEPPARD, Martin HOENIGL, Yohann LE GOVIC, Hamid BADALI, John W. BADDLEY, Jagdish CHANDER, Paul R. INGRAM, Diana L. PAKSTIS, Sibylle C. MELLINGHOFF, Serkan ATICI, Simone CESARO, Arunaloke CHAKRABARTI, Damien DUPONT, Gloria M. GONZALEZ, Lorant HATVANI, Raoul HERBRECHT, Galina KLYASOVA, Cornelia LASS-FLORL, Mihai MARES, Kathleen MULLANE, Donald C. VINH, Hilmar WISPLINGHOFF, Michaela LACKNER, Oliver A. CORNELY and Danila SEIDEL. Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScope (R)-Global Registry for Emerging Fungal Infections. The Journal of infection. London: Academic Press, 2020, vol. 81, No 5, p. 802-815. ISSN 0163-4453. Available from: https://dx.doi.org/10.1016/j.jinf.2020.08.015.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScope (R)-Global Registry for Emerging Fungal Infections
Authors SALMANTON-GARCIA, Jon, Philipp KOEHLER, Anupma KINDO, Iker FALCES-ROMERO, Julio GARCIA-RODRIGUEZ, Zdeněk RÁČIL (203 Czech Republic, belonging to the institution), Sharon C. A. CHEN, Nikolai KLIMKO, Guillaume DESOUBEAUX, George R. THOMPSON, Miguel-Angel BENITEZ-PENUELA, Jose-Yesid RODRIGUEZ, Donald C. SHEPPARD, Martin HOENIGL, Yohann LE GOVIC, Hamid BADALI, John W. BADDLEY, Jagdish CHANDER, Paul R. INGRAM, Diana L. PAKSTIS, Sibylle C. MELLINGHOFF, Serkan ATICI, Simone CESARO, Arunaloke CHAKRABARTI, Damien DUPONT, Gloria M. GONZALEZ, Lorant HATVANI, Raoul HERBRECHT, Galina KLYASOVA, Cornelia LASS-FLORL, Mihai MARES, Kathleen MULLANE, Donald C. VINH, Hilmar WISPLINGHOFF, Michaela LACKNER, Oliver A. CORNELY and Danila SEIDEL.
Edition The Journal of infection, London, Academic Press, 2020, 0163-4453.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30303 Infectious Diseases
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 6.072
RIV identification code RIV/00216224:14110/20:00117464
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.jinf.2020.08.015
UT WoS 000586323400017
Keywords in English Rare; Invasive fungal infections; Registry; Mold; Yeast
Tags 14110212, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 21/12/2020 09:26.
Abstract
Objectives: Emerging invasive fungal infections (IFI) have become a notable challenge. Apart from the more frequently described fusariosis, lomentosporiosis, mucormycosis, scedosporiosis, and certain dematiaceae or yeasts, little is known about extremely rare IFI. Methods: Extremely rare IFI collected in the FungiScope (R) registry were grouped as Dematiaceae, Hypocreales, Saccharomycetales, Eurotiales, Dermatomycetes, Agaricales, and Mucorales. Results: Between 2003 and June 2019, 186 extremely rare IFI were documented in FungiScope (R). Dematiaceae (35.5%), Hypocreales (23.1%), Mucorales (11.8%), and Saccharomycetales (11.3%) caused most IFI. Most patients had an underlying malignancy (38.7%) with acute leukemia accounting for 50% of cancers. Dissemination was observed in 26.9% of the patients. Complete or partial clinical response rate was 68.3%, being highest in Eurotiales (82.4%) and in Agaricales (80.0%). Overall mortality rate was 29.3%, ranging from 11.8% in Eurotiales to 50.0% in Mucorales. Conclusions: Physicians are confronted with a complex variety of fungal pathogens, for which treatment recommendations are lacking and successful outcome might be incidental. Through an international consortium of physicians and scientists, these cases of extremely rare IFI can be collected to further investigate their epidemiology and eventually identify effective treatment regimens. (C) 2020 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
PrintDisplayed: 10/7/2024 05:00