J 2020

Active surveillance for antibodies confirms circulation of lyssaviruses in Palearctic bats

SEIDLOVA, Veronika, Jan ZUKAL, Jiri BRICHTA, Nikolay ANISIMOV, Grzegorz APOZNAŃSKI et. al.

Basic information

Original name

Active surveillance for antibodies confirms circulation of lyssaviruses in Palearctic bats

Authors

SEIDLOVA, Veronika (guarantor), Jan ZUKAL (203 Czech Republic, belonging to the institution), Jiri BRICHTA, Nikolay ANISIMOV, Grzegorz APOZNAŃSKI, Hana BANDOUCHOVA, Tomáš BARTONIČKA (203 Czech Republic, belonging to the institution), Hana BERKOVÁ, Alexander D. BOTVINKIN, Tomas HEGER, Heliana DUNDAROVA, Tomasz KOKUREWICZ, Petr LINHART, Oleg L. ORLOV, Vladimir PIACEK, Primoz PRESETNIK, Alexandra P. SHUMKINA, Mikhail P. TIUNOV, Frantisek TREML and Jiri PIKULA

Edition

BMC Veterinary Research, London, BMC, 2020, 1746-6148

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

40301 Veterinary science

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.741

RIV identification code

RIV/00216224:14310/20:00117488

Organization unit

Faculty of Science

UT WoS

000599988800002

Keywords in English

blood samples; Chiroptera; Europe; rabies; seroprevalence; Siberia

Tags

Tags

International impact, Reviewed
Změněno: 13/1/2021 15:27, Mgr. Marie Šípková, DiS.

Abstract

V originále

Background: Palearctic bats host a diversity of lyssaviruses, though not the classical rabies virus (RABV). As surveillance for bat rabies over the Palearctic area covering Central and Eastern Europe and Siberian regions of Russia has been irregular, we lack data on geographic and seasonal patterns of the infection. Results: To address this, we undertook serological testing, using non-lethally sampled blood, on 1027 bats of 25 species in Bulgaria, the Czech Republic, Poland, Russia and Slovenia between 2014 and 2018. The indirect enzyme-linked immunosorbent assay (ELISA) detected rabies virus anti-glycoprotein antibodies in 33 bats, giving an overall seroprevalence of 3.2%. Bat species exceeding the seroconversion threshold included Myotis blythii, Myotis gracilis, Myotis petax, Myotis myotis, Murina hilgendorfi, Rhinolophus ferrumequinum and Vespertilio murinus. While Myotis species (84.8%) and adult females (48.5%) dominated in seropositive bats, juveniles of both sexes showed no difference in seroprevalence. Higher numbers tested positive when sampled during the active season (10.5%), as compared with the hibernation period (0.9%). Bat rabies seroprevalence was significantly higher in natural habitats (4.0%) compared with synanthropic roosts (1.2%). Importantly, in 2018, we recorded 73.1% seroprevalence in a cave containing a M. blythii maternity colony in the Altai Krai of Russia. Conclusions: Identification of such “hotspots” of non-RABV lyssavirus circulation not only provides important information for public health protection, it can also guide research activities aimed at more in-depth bat rabies studies. © 2020, The Author(s).