A review on the stereospecific fate and effects of chiral
conazole fungicides

J 2021

A review on the stereospecific fate and effects of chiral conazole fungicides

BIELSKÁ, Lucie, Sarah E. HALE a Lucia ŠKULCOVÁ

Základní údaje

Originální název

A review on the stereospecific fate and effects of chiral conazole fungicides

Autoři

BIELSKÁ, Lucie (203 Česká republika, garant, domácí), Sarah E. HALE (578 Norsko) a Lucia ŠKULCOVÁ (703 Slovensko, domácí)

Vydání

Science of the Total Environment, Amsterdam, Elsevier Science, 2021, 0048-9697

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 10.753

Kód RIV

RIV/00216224:14310/21:00118804

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1016/j.scitotenv.2020.141600

UT WoS

000585694600061

Klíčová slova anglicky

Pesticide; Agriculture; Enantiomer ratio; Degradation; Accumulation; Toxicity

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 31. 7. 2021 22:26, Mgr. Michaela Hylsová, Ph.D.

Anotace

V originále

The production and use of chiral pesticides are triggered by the need for more complex molecules capable of effectively combating a greater spectrum of pests and crop diseases, while sustaining high production yields. Currently, chiral pesticides comprise about 30% of all pesticides in use; however, some pesticide groups such as conazole fungicides (CFs) consist almost exclusively of chiral compounds. CFs are produced and field-applied as racemic (1:1) mixtures of two enantiomers (one chiral center in the molecule) or four diastereoisomers, i.e., two pairs of enantiomers (two chiral centers in the molecule). Research on the stereoselective environmental behavior and effects of chiral pesticides such as CFs has become increasingly important within the fields of environmental chemistry and ecotoxicology. This is motivated by the fact that currently, the fate and effects of chiral pesticides such as CFs that arise due to their stereoselectivity are not fully understood and integrated into risk assessment and regulatory decisions. In order to fill this gap, a summary of the state-of-the-art literature related to the stereospecific fate and effects of CFs is needed. This will also benefit the agrochemistry industry as they enhance their understanding of the environmental implications of CFs which will aid future research and development of chiral products. This review provides a collection of >80 stereoselective studies for CFs related to chiral analytical methods, fungicidal activity, non-target toxicity, and behavior of this broadly used pesticide class in the soil environment. In addition, the review sheds more light on mechanisms behind stereoselectivity, considers possible agricultural and environmental implications, and suggests future directions for the safe use of chiral CFs and the reduction of their environmental footprint.

Návaznosti

EF17_043/0009632, projekt VaV

Název: CETOCOEN Excellence

GJ18-14926Y, projekt VaV

Název: Enanatioselectivita současných chirálních conazolových fungicidů

LM2018121, projekt VaV

Název: Výzkumná infrastruktura RECETOX (Akronym: RECETOX RI)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, RECETOX RI

857560, interní kód MU
(Kód CEP: EF17_043/0009632)

Název: CETOCOEN Excellence (Akronym: CETOCOEN Excellence)

Investor: Evropská unie, CETOCOEN Excellence, Spreading excellence and widening participation

Citovat

BIELSKÁ, Lucie, Sarah E. HALE a Lucia ŠKULCOVÁ. A review on the stereospecific fate and effects of chiral conazole fungicides. Science of the Total Environment. Amsterdam: Elsevier Science, 2021, roč. 750, January, s. 1-13. ISSN 0048-9697. Dostupné z: https://dx.doi.org/10.1016/j.scitotenv.2020.141600.

@article{1715437,
   author = {Bielská, Lucie and Hale, Sarah E. and Škulcová, Lucia},
   article_location = {Amsterdam},
   article_number = {January},
   doi = {http://dx.doi.org/10.1016/j.scitotenv.2020.141600},
   keywords = {Pesticide; Agriculture; Enantiomer ratio; Degradation; Accumulation; Toxicity},
   language = {eng},
   issn = {0048-9697},
   journal = {Science of the Total Environment},
   title = {A review on the stereospecific fate and effects of chiral conazole fungicides},
   url = {https://www.sciencedirect.com/science/article/pii/S0048969720351299?via%3Dihub},
   volume = {750},
   year = {2021}
}

TY  - JOUR
ID  - 1715437
AU  - Bielská, Lucie - Hale, Sarah E. - Škulcová, Lucia
PY  - 2021
TI  - A review on the stereospecific fate and effects of chiral conazole fungicides
JF  - Science of the Total Environment
VL  - 750
IS  - January
SP  - 1-13
EP  - 1-13
PB  - Elsevier Science
SN  - 00489697
KW  - Pesticide
KW  - Agriculture
KW  - Enantiomer ratio
KW  - Degradation
KW  - Accumulation
KW  - Toxicity
UR  - https://www.sciencedirect.com/science/article/pii/S0048969720351299?via%3Dihub
L2  - https://www.sciencedirect.com/science/article/pii/S0048969720351299?via%3Dihub
N2  - The production and use of chiral pesticides are triggered by the need for more complex molecules capable of effectively combating a greater spectrum of pests and crop diseases, while sustaining high production yields. Currently, chiral pesticides comprise about 30% of all pesticides in use; however, some pesticide groups such as conazole fungicides (CFs) consist almost exclusively of chiral compounds. CFs are produced and field-applied as racemic (1:1) mixtures of two enantiomers (one chiral center in the molecule) or four diastereoisomers, i.e., two pairs of enantiomers (two chiral centers in the molecule). Research on the stereoselective environmental behavior and effects of chiral pesticides such as CFs has become increasingly important within the fields of environmental chemistry and ecotoxicology. This is motivated by the fact that currently, the fate and effects of chiral pesticides such as CFs that arise due to their stereoselectivity are not fully understood and integrated into risk assessment and regulatory decisions. In order to fill this gap, a summary of the state-of-the-art literature related to the stereospecific fate and effects of CFs is needed. This will also benefit the agrochemistry industry as they enhance their understanding of the environmental implications of CFs which will aid future research and development of chiral products. This review provides a collection of >80 stereoselective studies for CFs related to chiral analytical methods, fungicidal activity, non-target toxicity, and behavior of this broadly used pesticide class in the soil environment. In addition, the review sheds more light on mechanisms behind stereoselectivity, considers possible agricultural and environmental implications, and suggests future directions for the safe use of chiral CFs and the reduction of their environmental footprint.
ER  -

BIELSKÁ, Lucie, Sarah E. HALE a Lucia ŠKULCOVÁ. A review on the stereospecific fate and effects of chiral conazole fungicides. \textit{Science of the Total Environment}. Amsterdam: Elsevier Science, 2021, roč.~750, January, s.~1-13. ISSN~0048-9697. Dostupné z: https://dx.doi.org/10.1016/j.scitotenv.2020.141600.

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