The Role of Oxidative Stress in Early Brain Injury after
Subarachnoid Hemorrhage

J 2020

The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage

JELÍNEK, Matyáš, Michal JURAJDA a Kamil ĎURIŠ

Základní údaje

Originální název

The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage

Autoři

JELÍNEK, Matyáš (203 Česká republika, domácí), Michal JURAJDA (203 Česká republika, domácí) a Kamil ĎURIŠ (203 Česká republika, garant, domácí)

Vydání

Oxidative Medicine and Cellular Longevity, London, HINDAWI LTD, 2020, 1942-0900

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10601 Cell biology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 6.543

Kód RIV

RIV/00216224:14110/20:00117549

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1155/2020/8877116

UT WoS

000596448900001

Klíčová slova anglicky

Oxidative Stress; Early Brain Injury; Subarachnoid Hemorrhage

Štítky

14110224, 14110518, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 21. 1. 2021 08:02, Mgr. Tereza Miškechová

Anotace

V originále

This review focuses on the problem of oxidative stress in early brain injury (EBI) after spontaneous subarachnoid hemorrhage (SAH). EBI involves complex pathophysiological mechanisms, including oxidative stress. In the first section, we describe the main sources of free radicals in EBI. There are several sources of excessive generation of free radicals from mitochondrial free radicals' generation and endoplasmic reticulum stress, to hemoglobin and enzymatic free radicals' generation. The second part focuses on the disruption of antioxidant mechanisms in EBI. The third section describes some newly found molecular mechanisms and pathway involved in oxidative stress after EBI. The last section is dedicated to the pathophysiological mechanisms through which free radicals mediate early brain injury.

Návaznosti

MUNI/A/1453/2019, interní kód MU

Název: Příspěvek ke studiu molekulární, buněčné, tkáňové a systémové patofyziologie vybraných komplexních nemocí

Investor: Masarykova univerzita, Příspěvek ke studiu molekulární, buněčné, tkáňové a systémové patofyziologie vybraných komplexních nemocí, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

MUNI/11/SUP/24/2020, interní kód MU

Název: Pilotní studie ke studiu role cytokinů z rodiny interleukinu 6 a možnosti potlačení zánětu pomocí stimulace nervus vagus u experimentálního modelu subarachnoidálního krvácení a sepse (Akronym: Rodina IL-6 a SAH)

Investor: Masarykova univerzita, Pilotní studie ke studiu role cytokinů z rodiny interleukinu 6 a možnosti potlačení zánětu pomocí stimulace nervus vagus u experimentálního modelu subarachnoidálního krvácení a sepse

Citovat

JELÍNEK, Matyáš, Michal JURAJDA a Kamil ĎURIŠ. The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage. Oxidative Medicine and Cellular Longevity. London: HINDAWI LTD, 2020, roč. 2020, NOV 2020, s. 1-9. ISSN 1942-0900. Dostupné z: https://dx.doi.org/10.1155/2020/8877116.

@article{1718796,
   author = {Jelínek, Matyáš and Jurajda, Michal and Ďuriš, Kamil},
   article_location = {London},
   article_number = {NOV 2020},
   doi = {http://dx.doi.org/10.1155/2020/8877116},
   keywords = {Oxidative Stress; Early Brain Injury; Subarachnoid Hemorrhage},
   language = {eng},
   issn = {1942-0900},
   journal = {Oxidative Medicine and Cellular Longevity},
   title = {The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage},
   url = {https://www.hindawi.com/journals/omcl/2020/8877116/},
   volume = {2020},
   year = {2020}
}

TY  - JOUR
ID  - 1718796
AU  - Jelínek, Matyáš - Jurajda, Michal - Ďuriš, Kamil
PY  - 2020
TI  - The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage
JF  - Oxidative Medicine and Cellular Longevity
VL  - 2020
IS  - NOV 2020
SP  - 1-9
EP  - 1-9
PB  - HINDAWI LTD
SN  - 19420900
KW  - Oxidative Stress
KW  - Early Brain Injury
KW  - Subarachnoid Hemorrhage
UR  - https://www.hindawi.com/journals/omcl/2020/8877116/
L2  - https://www.hindawi.com/journals/omcl/2020/8877116/
N2  - This review focuses on the problem of oxidative stress in early brain injury (EBI) after spontaneous subarachnoid hemorrhage (SAH). EBI involves complex pathophysiological mechanisms, including oxidative stress. In the first section, we describe the main sources of free radicals in EBI. There are several sources of excessive generation of free radicals from mitochondrial free radicals' generation and endoplasmic reticulum stress, to hemoglobin and enzymatic free radicals' generation. The second part focuses on the disruption of antioxidant mechanisms in EBI. The third section describes some newly found molecular mechanisms and pathway involved in oxidative stress after EBI. The last section is dedicated to the pathophysiological mechanisms through which free radicals mediate early brain injury.
ER  -

JELÍNEK, Matyáš, Michal JURAJDA a Kamil ĎURIŠ. The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage. \textit{Oxidative Medicine and Cellular Longevity}. London: HINDAWI LTD, 2020, roč.~2020, NOV 2020, s.~1-9. ISSN~1942-0900. Dostupné z: https://dx.doi.org/10.1155/2020/8877116.

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