Photosynthesis-Inhibiting Activity of
1-[(2-Chlorophenyl)carbamoyl]- and
1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates

J 2017

Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates

GONĚC, Tomáš, J STRANIK, M PESKO, J KOS, M ORAVEC et. al.

Basic information

Original name

Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates

Authors

GONĚC, Tomáš, J STRANIK, M PESKO, J KOS, M ORAVEC, K KRALOVA and J JAMPILEK

Edition

Blood Cells, Molecules and Diseases, Orlando, Florida, Academic Press, 2017, 1079-9796

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.836

DOI

http://dx.doi.org/10.3390/molecules22071199

UT WoS

000406621300173

Keywords in English

alkylcarbamates; hydroxynaphthalene-carboxamides; PET inhibition; spinach chloroplasts; structure-activity relationships

Abstract

V originále

Eight 1-[(2-chlorophenyl)carbamoyl]naphthalen-2-yl alkylcarbamates and eight 1-[(2-nitrophenyl)carbamoyl]naphthalen-2-yl alkylcarbamates were tested for their activity related to the inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. The PET-inhibiting activity of the compounds was relatively low; the corresponding IC50 values ranged from 0.05 to 0.664 mmol/L; and the highest activity within the series of compounds was observed for 1-[(2-chlorophenyl)-carbamoyl] naphthalen-2-yl propylcarbamate. It has been proven that the compounds are PET-inhibitors in photosystem II. Despite rather low PET-inhibiting activities, primary structure-activity trends can be discussed.

Citovat

GONĚC, Tomáš, J STRANIK, M PESKO, J KOS, M ORAVEC, K KRALOVA and J JAMPILEK. Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates. Blood Cells, Molecules and Diseases. Orlando, Florida: Academic Press, 2017, vol. 22, No 7, 10 pp. ISSN 1079-9796. Available from: https://dx.doi.org/10.3390/molecules22071199.

@article{1727150,
   author = {Goněc, Tomáš and Stranik, J and Pesko, M and Kos, J and Oravec, M and Kralova, K and Jampilek, J},
   article_location = {Orlando, Florida},
   article_number = {7},
   doi = {http://dx.doi.org/10.3390/molecules22071199},
   keywords = {alkylcarbamates; hydroxynaphthalene-carboxamides; PET inhibition; spinach chloroplasts; structure-activity relationships},
   language = {eng},
   issn = {1079-9796},
   journal = {Blood Cells, Molecules and Diseases},
   title = {Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates},
   volume = {22},
   year = {2017}
}

TY  - JOUR
ID  - 1727150
AU  - Goněc, Tomáš - Stranik, J - Pesko, M - Kos, J - Oravec, M - Kralova, K - Jampilek, J
PY  - 2017
TI  - Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates
JF  - Blood Cells, Molecules and Diseases
VL  - 22
IS  - 7
PB  - Academic Press
SN  - 10799796
KW  - alkylcarbamates
KW  - hydroxynaphthalene-carboxamides
KW  - PET inhibition
KW  - spinach chloroplasts
KW  - structure-activity relationships
N2  - Eight 1-[(2-chlorophenyl)carbamoyl]naphthalen-2-yl alkylcarbamates and eight 1-[(2-nitrophenyl)carbamoyl]naphthalen-2-yl alkylcarbamates were tested for their activity related to the inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. The PET-inhibiting activity of the compounds was relatively low; the corresponding IC50 values ranged from 0.05 to 0.664 mmol/L; and the highest activity within the series of compounds was observed for 1-[(2-chlorophenyl)-carbamoyl] naphthalen-2-yl propylcarbamate. It has been proven that the compounds are PET-inhibitors in photosystem II. Despite rather low PET-inhibiting activities, primary structure-activity trends can be discussed.
ER  -

GONĚC, Tomáš, J STRANIK, M PESKO, J KOS, M ORAVEC, K KRALOVA and J JAMPILEK. Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates. \textit{Blood Cells, Molecules and Diseases}. Orlando, Florida: Academic Press, 2017, vol.~22, No~7, 10 pp. ISSN~1079-9796. Available from: https://dx.doi.org/10.3390/molecules22071199.

Detailed Information on Publication Record