The Dynamic Pathosome: A Surrogate for Health and Disease

C 2020

The Dynamic Pathosome: A Surrogate for Health and Disease

LENÁRT, Peter, Martin SCHERINGER a Julie DOBROVOLNÁ

Základní údaje

Originální název

The Dynamic Pathosome: A Surrogate for Health and Disease

Autoři

LENÁRT, Peter (703 Slovensko, garant, domácí), Martin SCHERINGER (756 Švýcarsko, domácí) a Julie DOBROVOLNÁ (203 Česká republika, domácí)

Vydání

Neuveden, Explaining Health Across the Sciences, od s. 271-288, 18 s. 2020

Nakladatel

Springer, Cham

Další údaje

Jazyk

angličtina

Typ výsledku

Kapitola resp. kapitoly v odborné knize

Obor

30304 Public and environmental health

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

elektronická verze "online"

Odkazy

URL

Kód RIV

RIV/00216224:14310/20:00117836

Organizační jednotka

Přírodovědecká fakulta

ISBN

978-3-030-52662-7

DOI

http://dx.doi.org/10.1007/978-3-030-52663-4_16

Klíčová slova anglicky

Disease; Health; Aging; Individualized medicine; Phenotype trajectories

Štítky

topvydavatel

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 17. 1. 2021 21:49, Mgr. Michaela Hylsová, Ph.D.

Anotace

V originále

Regardless of chosen definitions, health, as well as disease, are in their essence only labels describing two enormous groups of phenotypes. Thus, to study either health or disease, we need to understand the factors affecting the development of specific phenotypes. The current paradigm used to explain the development of phenotypes oversimplifies the entire process by omitting the key factor of time. The novel concept of the dynamic pathosome aims to provide a much more detailed picture than the current paradigm. It provides a novel theoretical framework as well as practical applications, but most importantly can change how we perceive health and disease. This chapter reviews the concept of the dynamic pathosome and the benefits it could offer to biomedicine.

Návaznosti

EF15_003/0000469, projekt VaV

Název: Cetocoen Plus

EF16_013/0001761, projekt VaV

Název: RECETOX RI

LM2015051, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX RI)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Výzkumná infrastruktura RECETOX

Citovat

LENÁRT, Peter, Martin SCHERINGER a Julie DOBROVOLNÁ. The Dynamic Pathosome: A Surrogate for Health and Disease. Online. In Jonathan ShollSuresh I.S. Rattan. Explaining Health Across the Sciences. Neuveden: Springer, Cham, 2020, s. 271-288. ISBN 978-3-030-52662-7. Dostupné z: https://dx.doi.org/10.1007/978-3-030-52663-4_16.

@inbook{1729230,
   author = {Lenárt, Peter and Scheringer, Martin and Dobrovolná, Julie},
   address = {Neuveden},
   booktitle = {Explaining Health Across the Sciences},
   doi = {http://dx.doi.org/10.1007/978-3-030-52663-4_16},
   editor = {Jonathan ShollSuresh I.S. Rattan},
   keywords = {Disease; Health; Aging; Individualized medicine; Phenotype trajectories},
   howpublished = {elektronická verze "online"},
   language = {eng},
   location = {Neuveden},
   isbn = {978-3-030-52662-7},
   pages = {271-288},
   publisher = {Springer, Cham},
   title = {The Dynamic Pathosome: A Surrogate for Health and Disease},
   url = {https://link.springer.com/chapter/10.1007/978-3-030-52663-4_16},
   year = {2020}
}

TY  - CHAP
ID  - 1729230
AU  - Lenárt, Peter - Scheringer, Martin - Dobrovolná, Julie
PY  - 2020
TI  - The Dynamic Pathosome: A Surrogate for Health and Disease
VL  - Neuveden
PB  - Springer, Cham
CY  - Neuveden
SN  - 9783030526627
KW  - Disease
KW  - Health
KW  - Aging
KW  - Individualized medicine
KW  - Phenotype trajectories
UR  - https://link.springer.com/chapter/10.1007/978-3-030-52663-4_16
L2  - https://link.springer.com/chapter/10.1007/978-3-030-52663-4_16
N2  - Regardless of chosen definitions, health, as well as disease, are in their essence only labels describing two enormous groups of phenotypes. Thus, to study either health or disease, we need to understand the factors affecting the development of specific phenotypes. The current paradigm used to explain the development of phenotypes oversimplifies the entire process by omitting the key factor of time. The novel concept of the dynamic pathosome aims to provide a much more detailed picture than the current paradigm. It provides a novel theoretical framework as well as practical applications, but most importantly can change how we perceive health and disease. This chapter reviews the concept of the dynamic pathosome and the benefits it could offer to biomedicine.
ER  -

LENÁRT, Peter, Martin SCHERINGER a Julie DOBROVOLNÁ. The Dynamic Pathosome: A Surrogate for Health and Disease. Online. In Jonathan ShollSuresh I.S. Rattan. \textit{Explaining Health Across the Sciences}. Neuveden: Springer, Cham, 2020, s.~271-288. ISBN~978-3-030-52662-7. Dostupné z: https://dx.doi.org/10.1007/978-3-030-52663-4\_{}16.

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