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@inbook{1729230, author = {Lenárt, Peter and Scheringer, Martin and Dobrovolná, Julie}, address = {Neuveden}, booktitle = {Explaining Health Across the Sciences}, doi = {http://dx.doi.org/10.1007/978-3-030-52663-4_16}, editor = {Jonathan ShollSuresh I.S. Rattan}, keywords = {Disease; Health; Aging; Individualized medicine; Phenotype trajectories}, howpublished = {elektronická verze "online"}, language = {eng}, location = {Neuveden}, isbn = {978-3-030-52662-7}, pages = {271-288}, publisher = {Springer, Cham}, title = {The Dynamic Pathosome: A Surrogate for Health and Disease}, url = {https://link.springer.com/chapter/10.1007/978-3-030-52663-4_16}, year = {2020} }
TY - CHAP ID - 1729230 AU - Lenárt, Peter - Scheringer, Martin - Dobrovolná, Julie PY - 2020 TI - The Dynamic Pathosome: A Surrogate for Health and Disease VL - Neuveden PB - Springer, Cham CY - Neuveden SN - 9783030526627 KW - Disease KW - Health KW - Aging KW - Individualized medicine KW - Phenotype trajectories UR - https://link.springer.com/chapter/10.1007/978-3-030-52663-4_16 L2 - https://link.springer.com/chapter/10.1007/978-3-030-52663-4_16 N2 - Regardless of chosen definitions, health, as well as disease, are in their essence only labels describing two enormous groups of phenotypes. Thus, to study either health or disease, we need to understand the factors affecting the development of specific phenotypes. The current paradigm used to explain the development of phenotypes oversimplifies the entire process by omitting the key factor of time. The novel concept of the dynamic pathosome aims to provide a much more detailed picture than the current paradigm. It provides a novel theoretical framework as well as practical applications, but most importantly can change how we perceive health and disease. This chapter reviews the concept of the dynamic pathosome and the benefits it could offer to biomedicine. ER -
LENÁRT, Peter, Martin SCHERINGER a Julie DOBROVOLNÁ. The Dynamic Pathosome: A Surrogate for Health and Disease. Online. In Jonathan ShollSuresh I.S. Rattan. \textit{Explaining Health Across the Sciences}. Neuveden: Springer, Cham, 2020, s.~271-288. ISBN~978-3-030-52662-7. Dostupné z: https://dx.doi.org/10.1007/978-3-030-52663-4\_{}16.
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