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@article{1746829,
author = {Capoor, M. N. and Ahmed, F. S. and McDowell, A. and Slabý, Ondřej},
article_location = {LAUSANNE},
article_number = {DEC 2020},
doi = {http://dx.doi.org/10.3389/fcimb.2020.605334},
keywords = {SARS-CoV-2; COVID-19; T-cell; human coronaviruses; immunity; contact tracing; children},
language = {eng},
issn = {2235-2988},
journal = {FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY},
title = {Is the "Common Cold" Our Greatest Ally in the Battle Against SARS-CoV-2?},
url = {https://www.frontiersin.org/articles/10.3389/fcimb.2020.605334/full},
volume = {10},
year = {2020}
}
TY - JOUR
ID - 1746829
AU - Capoor, M. N. - Ahmed, F. S. - McDowell, A. - Slabý, Ondřej
PY - 2020
TI - Is the "Common Cold" Our Greatest Ally in the Battle Against SARS-CoV-2?
JF - FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
VL - 10
IS - DEC 2020
SP - 1-5
EP - 1-5
PB - FRONTIERS MEDIA SA
SN - 22352988
KW - SARS-CoV-2
KW - COVID-19
KW - T-cell
KW - human coronaviruses
KW - immunity
KW - contact tracing
KW - children
UR - https://www.frontiersin.org/articles/10.3389/fcimb.2020.605334/full
N2 - The discovery of T-cell responses to SARS-CoV-2 in non-infected individuals indicates cross-reactive immune memory from prior exposure to human coronaviruses (HCoV) that cause the common cold. This raises the possibility that "immunity" could exist within populations at rates that may be higher than serology studies estimate. Besides specialized research labs, however, there is limited ability to measure HCoV CD4+ and CD8+ T-cell responses to SARS-CoV-2 infection, which currently impedes interpretation of any potential correlation between COVID-19 disease pathogenesis and the calibration of pandemic control measures. Given this limited testing ability, an alternative approach would be to exploit the large cohort of currently available data from which statistically significant associations may be generated. This would necessitate the merging of several public databases including patient and contact tracing, which could be created by relevant public health organizations. Including data from both symptomatic and asymptomatic patients in SARS-CoV-2 databases and surveillance systems could provide the necessary information to allow for more informed decisions.
ER -
CAPOOR, M. N., F. S. AHMED, A. MCDOWELL a Ondřej SLABÝ. Is the ''Common Cold'' Our Greatest Ally in the Battle Against SARS-CoV-2? \textit{FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY}. LAUSANNE: FRONTIERS MEDIA SA, 2020, roč.~10, DEC 2020, s.~1-5. ISSN~2235-2988. Dostupné z: https://dx.doi.org/10.3389/fcimb.2020.605334.
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