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@article{1751120,
author = {Procházková, Michaela and Škubník, Karel and Füzik, Tibor and Mukhamedova, Liya and Pridal, A. and Plevka, Pavel},
article_location = {OXFORD},
article_number = {DEC},
doi = {http://dx.doi.org/10.1016/j.coviro.2020.06.007},
keywords = {DEFORMED WING VIRUS; BEE PARALYSIS VIRUS; PICORNA-LIKE VIRUS; APIS-MELLIFERA L.; IN-VITRO; IDENTIFICATION; DECLINES; TRANSMISSION; PARTICLES; SACBROOD},
language = {eng},
issn = {1879-6257},
journal = {CURRENT OPINION IN VIROLOGY},
title = {Virion structures and genome delivery of honeybee viruses},
url = {https://www.sciencedirect.com/science/article/pii/S1879625720300390?via%3Dihub},
volume = {45},
year = {2020}
}
TY - JOUR
ID - 1751120
AU - Procházková, Michaela - Škubník, Karel - Füzik, Tibor - Mukhamedova, Liya - Pridal, A. - Plevka, Pavel
PY - 2020
TI - Virion structures and genome delivery of honeybee viruses
JF - CURRENT OPINION IN VIROLOGY
VL - 45
IS - DEC
SP - 17-24
EP - 17-24
PB - ELSEVIER SCI LTD
SN - 18796257
KW - DEFORMED WING VIRUS
KW - BEE PARALYSIS VIRUS
KW - PICORNA-LIKE VIRUS
KW - APIS-MELLIFERA L.
KW - IN-VITRO
KW - IDENTIFICATION
KW - DECLINES
KW - TRANSMISSION
KW - PARTICLES
KW - SACBROOD
UR - https://www.sciencedirect.com/science/article/pii/S1879625720300390?via%3Dihub
N2 - The western honeybee is the primary pollinator of numerous food crops. Furthermore, honeybees are essential for ecosystem stability by sustaining the diversity and abundance of wild flowering plants. However, the worldwide population of honeybees is under pressure from environmental stress and pathogens. Viruses from the families Iflaviridae and Dicistroviridae, together with their vector, the parasitic mite Varroa destructor, are the major threat to the world's honeybees. Dicistroviruses and iflaviruses have capsids with icosahedral symmetries. Acidic pH triggers the genome release of both dicistroviruses and iflaviruses. The capsids of iflaviruses expand, whereas those of dicistroviruses remain compact until the genome release. Furthermore, dicistroviruses use inner capsid proteins, whereas iflaviruses employ protruding domains or minor capsid proteins from the virion surface to penetrate membranes and deliver their genomes into the cell cytoplasm. The structural characterization of the infection process opens up possibilities for the development of antiviral compounds.
ER -
PROCHÁZKOVÁ, Michaela, Karel ŠKUBNÍK, Tibor FÜZIK, Liya MUKHAMEDOVA, A. PRIDAL a Pavel PLEVKA. Virion structures and genome delivery of honeybee viruses. \textit{CURRENT OPINION IN VIROLOGY}. OXFORD: ELSEVIER SCI LTD, 2020, roč.~45, DEC, s.~17-24. ISSN~1879-6257. Dostupné z: https://dx.doi.org/10.1016/j.coviro.2020.06.007.
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