| HISGEN, L., L. ABEL, L. K. HALLMAIER-WACKER, S. LUEERT, U. SIEBERT, M. FAEHNDRICH, E. STRAUSS, U. VOIGT, Markéta NOVÁKOVÁ, David ŠMAJS a S. KNAUF. High syphilis seropositivity in European brown hares (Lepus europaeus), Lower Saxony, Germany. Transboundary and Emerging Diseases. Hoboken: Wiley-Blackwell, 2020, roč. 67, č. 5, s. 2240-2244. ISSN 1865-1674. Dostupné z: https://dx.doi.org/10.1111/tbed.13551. |
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@article{1753389,
author = {Hisgen, L. and Abel, L. and HallmaierandWacker, L. K. and Lueert, S. and Siebert, U. and Faehndrich, M. and Strauss, E. and Voigt, U. and Nováková, Markéta and Šmajs, David and Knauf, S.},
article_location = {Hoboken},
article_number = {5},
doi = {http://dx.doi.org/10.1111/tbed.13551},
keywords = {lagomorpha; Lepus europaeus; rabbit; serology; spirochaete; Treponema paraluisleporidarum},
language = {eng},
issn = {1865-1674},
journal = {Transboundary and Emerging Diseases},
title = {High syphilis seropositivity in European brown hares (Lepus europaeus), Lower Saxony, Germany},
url = {https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/tbed.13551},
volume = {67},
year = {2020}
}
TY - JOUR
ID - 1753389
AU - Hisgen, L. - Abel, L. - Hallmaier-Wacker, L. K. - Lueert, S. - Siebert, U. - Faehndrich, M. - Strauss, E. - Voigt, U. - Nováková, Markéta - Šmajs, David - Knauf, S.
PY - 2020
TI - High syphilis seropositivity in European brown hares (Lepus europaeus), Lower Saxony, Germany
JF - Transboundary and Emerging Diseases
VL - 67
IS - 5
SP - 2240-2244
EP - 2240-2244
PB - Wiley-Blackwell
SN - 18651674
KW - lagomorpha
KW - Lepus europaeus
KW - rabbit
KW - serology
KW - spirochaete
KW - Treponema paraluisleporidarum
UR - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/tbed.13551
N2 - The lagomorph-infecting Treponema paraluisleporidarum is a close relative of the human syphilis-bacterium Treponema pallidum. There is a paucity of information on the epidemiology of hare syphilis and its relationship to the rabbit- and human-infecting treponemes that cause syphilis. In our study, we tested 734 serum samples from European brown hares (Lepus europaeus) collected between 2007 and 2019 in the federal state of Lower Saxony, Germany, for the presence of antibodies against T. paraluisleporidarum. Since T. paraluisleporidarum cross-reacts with T. pallidum antigen, we used a commercially available T. pallidum-particle agglutination (TP-PA) assay to test for the presence of antibodies. A high seropositivity (n = 405/734) was detected. An additional 233 serum samples were retested using a fluorescent treponemal antibody absorption test to confirm the results of the TP-PA assay. Our results show that infection is widespread in Lower Saxony and suggest a horizontal (sexual) transmission mode since adult hares show significantly higher seropositivity than subadults (odds ratio: 0.03 [95% CI 0.02-0.05], p < .0001). No difference was detected based on gender (odds ratio: 0.79 [95% Cl 0.58-1.07], p = .1283). Further studies are warranted to genetically characterize the T. paraluisleporidarum strains that infect wild hares.
ER -
HISGEN, L., L. ABEL, L. K. HALLMAIER-WACKER, S. LUEERT, U. SIEBERT, M. FAEHNDRICH, E. STRAUSS, U. VOIGT, Markéta NOVÁKOVÁ, David ŠMAJS a S. KNAUF. High syphilis seropositivity in European brown hares (Lepus europaeus), Lower Saxony, Germany. \textit{Transboundary and Emerging Diseases}. Hoboken: Wiley-Blackwell, 2020, roč.~67, č.~5, s.~2240-2244. ISSN~1865-1674. Dostupné z: https://dx.doi.org/10.1111/tbed.13551.
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