Voiding recovery after radical parametrectomy in cervical
cancer patients: An international prospective multicentre trial
- SENTIX

J 2021

Voiding recovery after radical parametrectomy in cervical cancer patients: An international prospective multicentre trial - SENTIX

ZAPARDIEL, I., Roman KOCIAN, C. KOHLER, Jaroslav KLAT, Anna GERMANOVA et. al.

Základní údaje

Originální název

Voiding recovery after radical parametrectomy in cervical cancer patients: An international prospective multicentre trial - SENTIX

Autoři

ZAPARDIEL, I. (garant), Roman KOCIAN (203 Česká republika), C. KOHLER, Jaroslav KLAT (203 Česká republika), Anna GERMANOVA (203 Česká republika), A. JACOB, Sylva BAJSOVA (203 Česká republika), G. BOHMER, L. LAY, B. GIL-IBANEZ, Pavel HAVELKA (203 Česká republika), B. KIPP, G. SZEWCZYK, R. TOTH, J. C. STARINGER, J. DE SANTIAGO, P. J. CORONADO, R. POKA, R. LAKY, M. LUYCKX, M. FASTREZ, Ladislav DUŠEK (203 Česká republika, domácí), A. HERNANDEZ a David CIBULA (203 Česká republika)

Vydání

Gynecologic Oncology, SAN DIEGO, ACADEMIC PRESS INC ELSEVIER SCIENCE, 2021, 0090-8258

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30214 Obstetrics and gynaecology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 5.304

Kód RIV

RIV/00216224:14110/21:00121473

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.ygyno.2020.12.018

UT WoS

000620805400014

Klíčová slova anglicky

Radical hysterectomy; Parametrectomy; Cervical cancer; Voiding recovery; Nerve-sparing techniques

Štítky

14119612, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 26. 4. 2021 14:06, Mgr. Tereza Miškechová

Anotace

V originále

OBJECTIVE: Voiding dysfunctions represent a leading morbidity after radical hysterectomy performed in patients with early-stage cervical cancer. The aim of this study was to perform ad hoc analysis of factors influencing voiding recovery in SENTIX (SENTinel lymph node biopsy in cervIX cancer) trial. METHODS: The SENTIX trial (47 sites, 18 countries) is a prospective study on sentinel lymph node biopsy without pelvic lymphadenectomy in patients with early-stage cervical cancer. Overall, the data of 300 patients were analysed. Voiding recovery was defined as the number of days from surgery to bladder catheter/epicystostomy removal or to post-voiding urine residuum <= 50 mL. RESULTS: The median voiding recovery time was three days (5th-95th percentile: 0-21): 235 (78.3%) patients recovered in <7 days and 293 (97.7%) in 30 days. Only seven (2.3%) patients recovered after 0.001) significantly influenced voiding recovery 7 days post-surgery. Type-B parametrectomy was associated with a higher risk of delayed voiding recovery than type-C1 (OR = 4.69; p = 0.023 vs. OR = 3.62; p = 0.052, respectively), followed by type-C2 (OR = 5.84; p = 0.011). Both previous pregnancy and type C2 parametrectomy indepen-dently prolonged time to voiding recovery by two days. CONCLUSIONS: Time to voiding recovery is significantly related to previous pregnancy and type of parametrectomy but it is not influenced by surgical approach (open vs minimally invasive), age, or BMI. Type B parametrectomy, without direct visualisation of nerves, was associated with longer recovery than nerve-sparing type C1. Importantly, voiding dysfunctions after radical surgery are temporary, and the majority of the patients recover in less than 30 days, including patients after C2 parametrectomy. (C) 2020 Elsevier Inc. All rights reserved.

Citovat

ZAPARDIEL, I., Roman KOCIAN, C. KOHLER, Jaroslav KLAT, Anna GERMANOVA, A. JACOB, Sylva BAJSOVA, G. BOHMER, L. LAY, B. GIL-IBANEZ, Pavel HAVELKA, B. KIPP, G. SZEWCZYK, R. TOTH, J. C. STARINGER, J. DE SANTIAGO, P. J. CORONADO, R. POKA, R. LAKY, M. LUYCKX, M. FASTREZ, Ladislav DUŠEK, A. HERNANDEZ a David CIBULA. Voiding recovery after radical parametrectomy in cervical cancer patients: An international prospective multicentre trial - SENTIX. Gynecologic Oncology. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2021, roč. 160, č. 3, s. 729-734. ISSN 0090-8258. Dostupné z: https://dx.doi.org/10.1016/j.ygyno.2020.12.018.

@article{1763417,
   author = {Zapardiel, I. and Kocian, Roman and Kohler, C. and Klat, Jaroslav and Germanova, Anna and Jacob, A. and Bajsova, Sylva and Bohmer, G. and Lay, L. and GilandIbanez, B. and Havelka, Pavel and Kipp, B. and Szewczyk, G. and Toth, R. and Staringer, J. C. and De Santiago, J. and Coronado, P. J. and Poka, R. and Laky, R. and Luyckx, M. and Fastrez, M. and Dušek, Ladislav and Hernandez, A. and Cibula, David},
   article_location = {SAN DIEGO},
   article_number = {3},
   doi = {http://dx.doi.org/10.1016/j.ygyno.2020.12.018},
   keywords = {Radical hysterectomy; Parametrectomy; Cervical cancer; Voiding recovery; Nerve-sparing techniques},
   language = {eng},
   issn = {0090-8258},
   journal = {Gynecologic Oncology},
   title = {Voiding recovery after radical parametrectomy in cervical cancer patients: An international prospective multicentre trial - SENTIX},
   url = {https://www.sciencedirect.com/science/article/pii/S0090825820342219?via%3Dihub},
   volume = {160},
   year = {2021}
}

TY  - JOUR
ID  - 1763417
AU  - Zapardiel, I. - Kocian, Roman - Kohler, C. - Klat, Jaroslav - Germanova, Anna - Jacob, A. - Bajsova, Sylva - Bohmer, G. - Lay, L. - Gil-Ibanez, B. - Havelka, Pavel - Kipp, B. - Szewczyk, G. - Toth, R. - Staringer, J. C. - De Santiago, J. - Coronado, P. J. - Poka, R. - Laky, R. - Luyckx, M. - Fastrez, M. - Dušek, Ladislav - Hernandez, A. - Cibula, David
PY  - 2021
TI  - Voiding recovery after radical parametrectomy in cervical cancer patients: An international prospective multicentre trial - SENTIX
JF  - Gynecologic Oncology
VL  - 160
IS  - 3
SP  - 729-734
EP  - 729-734
PB  - ACADEMIC PRESS INC ELSEVIER SCIENCE
SN  - 00908258
KW  - Radical hysterectomy
KW  - Parametrectomy
KW  - Cervical cancer
KW  - Voiding recovery
KW  - Nerve-sparing techniques
UR  - https://www.sciencedirect.com/science/article/pii/S0090825820342219?via%3Dihub
N2  - OBJECTIVE: Voiding dysfunctions represent a leading morbidity after radical hysterectomy performed in patients with early-stage cervical cancer. The aim of this study was to perform ad hoc analysis of factors influencing voiding recovery in SENTIX (SENTinel lymph node biopsy in cervIX cancer) trial. METHODS: The SENTIX trial (47 sites, 18 countries) is a prospective study on sentinel lymph node biopsy without pelvic lymphadenectomy in patients with early-stage cervical cancer. Overall, the data of 300 patients were analysed. Voiding recovery was defined as the number of days from surgery to bladder catheter/epicystostomy removal or to post-voiding urine residuum <= 50 mL. RESULTS: The median voiding recovery time was three days (5th-95th percentile: 0-21): 235 (78.3%) patients recovered in <7 days and 293 (97.7%) in 30 days. Only seven (2.3%) patients recovered after 0.001) significantly influenced voiding recovery 7 days post-surgery. Type-B parametrectomy was associated with a higher risk of delayed voiding recovery than type-C1 (OR = 4.69; p = 0.023 vs. OR = 3.62; p = 0.052, respectively), followed by type-C2 (OR = 5.84; p = 0.011). Both previous pregnancy and type C2 parametrectomy indepen-dently prolonged time to voiding recovery by two days. CONCLUSIONS: Time to voiding recovery is significantly related to previous pregnancy and type of parametrectomy but it is not influenced by surgical approach (open vs minimally invasive), age, or BMI. Type B parametrectomy, without direct visualisation of nerves, was associated with longer recovery than nerve-sparing type C1. Importantly, voiding dysfunctions after radical surgery are temporary, and the majority of the patients recover in less than 30 days, including patients after C2 parametrectomy. (C) 2020 Elsevier Inc. All rights reserved.
ER  -

ZAPARDIEL, I., Roman KOCIAN, C. KOHLER, Jaroslav KLAT, Anna GERMANOVA, A. JACOB, Sylva BAJSOVA, G. BOHMER, L. LAY, B. GIL-IBANEZ, Pavel HAVELKA, B. KIPP, G. SZEWCZYK, R. TOTH, J. C. STARINGER, J. DE SANTIAGO, P. J. CORONADO, R. POKA, R. LAKY, M. LUYCKX, M. FASTREZ, Ladislav DUŠEK, A. HERNANDEZ a David CIBULA. Voiding recovery after radical parametrectomy in cervical cancer patients: An international prospective multicentre trial - SENTIX. \textit{Gynecologic Oncology}. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2021, roč.~160, č.~3, s.~729-734. ISSN~0090-8258. Dostupné z: https://dx.doi.org/10.1016/j.ygyno.2020.12.018.

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