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@article{1767716,
author = {Sochorová, Lenka and Baroň, Mojmír and Dadáková, Kateřina and Kašparovský, Tomáš and Sochor, Jiří},
article_number = {7},
doi = {http://dx.doi.org/10.3390/molecules26072099},
keywords = {grape seed extract; antioxidants; cadmium; rattus norvegicus; biochemical markers; protective effect},
language = {eng},
issn = {1420-3049},
journal = {Molecules},
title = {Health Beneficial Properties of Grapevine Seed Extract and Its Influence on Selected Biochemical Markers in the Blood, Liver and Kidneys of Rattus norvegicus},
url = {https://www.mdpi.com/1420-3049/26/7/2099},
volume = {26},
year = {2021}
}
TY - JOUR
ID - 1767716
AU - Sochorová, Lenka - Baroň, Mojmír - Dadáková, Kateřina - Kašparovský, Tomáš - Sochor, Jiří
PY - 2021
TI - Health Beneficial Properties of Grapevine Seed Extract and Its Influence on Selected Biochemical Markers in the Blood, Liver and Kidneys of Rattus norvegicus
JF - Molecules
VL - 26
IS - 7
SP - 1-17
EP - 1-17
PB - MDPI
SN - 14203049
KW - grape seed extract
KW - antioxidants
KW - cadmium
KW - rattus norvegicus
KW - biochemical markers
KW - protective effect
UR - https://www.mdpi.com/1420-3049/26/7/2099
N2 - Cadmium (Cd) is a heavy metal that occurs in all areas of the environment, including the food chain. In the body, it causes oxidative stress by producing free radicals that are harmful to the cells. Grape seed extract (GSE) contains a wide range of biologically active components that help to neutralize the adverse effects of free radicals. In this study, the effects of GSE prepared form semi-resistant grapevine cultivar Cerason, which is rich in phenolics, on biochemical markers of brown rats exposed to the effects of cadmium were monitored. GSE increased the plasma antioxidant activity and, in the kidneys and the liver, Cd content was significantly lowered by GSE co-administration. Accordingly, the increase in creatinine content and alanine aminotransferase activity and the decrease of catalase and superoxide dismutase activities caused by cadmium were slowed down by GSE co-administration. The results of this work reveal that grape seed extract offers a protective effect against the intake of heavy metals into the organism.
ER -
SOCHOROVÁ, Lenka, Mojmír BAROŇ, Kateřina DADÁKOVÁ, Tomáš KAŠPAROVSKÝ a Jiří SOCHOR. Health Beneficial Properties of Grapevine Seed Extract and Its Influence on Selected Biochemical Markers in the Blood, Liver and Kidneys of Rattus norvegicus. \textit{Molecules}. MDPI, 2021, roč.~26, č.~7, s.~1-17. ISSN~1420-3049. Dostupné z: https://dx.doi.org/10.3390/molecules26072099.
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