Stroke 20 20: Implementation goals for intravenous thrombolysis

J 2021

Stroke 20 20: Implementation goals for intravenous thrombolysis

MIKULÍK, Robert, Michal BAR, David CERNIK, Roman HERZIG, René JURA et. al.

Základní údaje

Originální název

Stroke 20 20: Implementation goals for intravenous thrombolysis

Autoři

MIKULÍK, Robert (203 Česká republika, garant, domácí), Michal BAR (203 Česká republika), David CERNIK (203 Česká republika), Roman HERZIG (203 Česká republika), René JURA (203 Česká republika, domácí), Lubomir JURAK (203 Česká republika), Jiri NEUMANN (203 Česká republika), Daniel SANAK (203 Česká republika), Svatopluk OSTRY (203 Česká republika), Petr SEVCIK (203 Česká republika), Ondrej SKODA (203 Česká republika), David SKOLOUDIK (203 Česká republika), Daniel VACLAVIK (203 Česká republika) a Ales TOMEK (203 Česká republika)

Vydání

EUROPEAN STROKE JOURNAL, LONDON, SAGE PUBLICATIONS LTD, 2021, 2396-9873

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 5.894

Kód RIV

RIV/00216224:14110/21:00121597

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1177/23969873211007684

UT WoS

000641919100001

Klíčová slova anglicky

Thrombolytic rate; stroke care management; implementation of thrombolysis; acute stroke care

Štítky

14110127, 14110221, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 2. 2022 10:29, Mgr. Tereza Miškechová

Anotace

V originále

Introduction Knowledge of the implementation gap would facilitate the use of intravenous thrombolysis in stroke, which is still low in many countries. The study was conducted to identify national implementation targets for the utilisation and logistics of intravenous thrombolysis. Material and Method Multicomponent interventions by stakeholders in health care to optimise prehospital and hospital management with the goal of fast and accessible intravenous thrombolysis for every candidate. Implementation results were documented from prospectively collected cases in all 45 stroke centres nationally. The thrombolytic rate was calculated from the total number of all ischemic strokes in the population of the Czech Republic since 2004. Results Thrombolytic rates of 1.3 (95%CI 1.1 to 1.4), 5.4 (95%CI 5.1 to 5.7), 13.6 (95%CI 13.1 to 14.0), 23.3 (95%CI 22.8 to 23.9), and 23.5% (95%CI 23.0 to 24.1%) were achieved in 2005, 2009, 2014, 2017, and 2018, respectively. National median door-to-needle times were 60-70 minutes before 2012 and then decreased progressively every year to 25 minutes (IQR 17 to 36) in 2018. In 2018, 33% of both university and non-university hospitals achieved median door-to-needle time <= 20 minutes. In 2018, door-to-needle times <= 20, <= 45, and <= 60 minutes were achieved in 39, 85, and 93% of patients. Discussion Thrombolysis can be provided to >= 20% of all ischemic strokes nationwide and it is realistic to achieve median door-to-needle time 20 minutes. Conclusion Stroke 20-20 could serve as national implementation target for intravenous thrombolysis and country specific implementation policies should be applied to achieve such target.

Návaznosti

90128, velká výzkumná infrastruktura

Název: CZECRIN III

Citovat

MIKULÍK, Robert, Michal BAR, David CERNIK, Roman HERZIG, René JURA, Lubomir JURAK, Jiri NEUMANN, Daniel SANAK, Svatopluk OSTRY, Petr SEVCIK, Ondrej SKODA, David SKOLOUDIK, Daniel VACLAVIK a Ales TOMEK. Stroke 20 20: Implementation goals for intravenous thrombolysis. EUROPEAN STROKE JOURNAL. LONDON: SAGE PUBLICATIONS LTD, 2021, roč. 6, č. 2, s. 151-159. ISSN 2396-9873. Dostupné z: https://dx.doi.org/10.1177/23969873211007684.

@article{1769257,
   author = {Mikulík, Robert and Bar, Michal and Cernik, David and Herzig, Roman and Jura, René and Jurak, Lubomir and Neumann, Jiri and Sanak, Daniel and Ostry, Svatopluk and Sevcik, Petr and Skoda, Ondrej and Skoloudik, David and Vaclavik, Daniel and Tomek, Ales},
   article_location = {LONDON},
   article_number = {2},
   doi = {http://dx.doi.org/10.1177/23969873211007684},
   keywords = {Thrombolytic rate; stroke care management; implementation of thrombolysis; acute stroke care},
   language = {eng},
   issn = {2396-9873},
   journal = {EUROPEAN STROKE JOURNAL},
   title = {Stroke 20 20: Implementation goals for intravenous thrombolysis},
   url = {https://journals.sagepub.com/doi/pdf/10.1177/23969873211007684},
   volume = {6},
   year = {2021}
}

TY  - JOUR
ID  - 1769257
AU  - Mikulík, Robert - Bar, Michal - Cernik, David - Herzig, Roman - Jura, René - Jurak, Lubomir - Neumann, Jiri - Sanak, Daniel - Ostry, Svatopluk - Sevcik, Petr - Skoda, Ondrej - Skoloudik, David - Vaclavik, Daniel - Tomek, Ales
PY  - 2021
TI  - Stroke 20 20: Implementation goals for intravenous thrombolysis
JF  - EUROPEAN STROKE JOURNAL
VL  - 6
IS  - 2
SP  - 151-159
EP  - 151-159
PB  - SAGE PUBLICATIONS LTD
SN  - 23969873
KW  - Thrombolytic rate
KW  - stroke care management
KW  - implementation of thrombolysis
KW  - acute stroke care
UR  - https://journals.sagepub.com/doi/pdf/10.1177/23969873211007684
N2  - Introduction Knowledge of the implementation gap would facilitate the use of intravenous thrombolysis in stroke, which is still low in many countries. The study was conducted to identify national implementation targets for the utilisation and logistics of intravenous thrombolysis. Material and Method Multicomponent interventions by stakeholders in health care to optimise prehospital and hospital management with the goal of fast and accessible intravenous thrombolysis for every candidate. Implementation results were documented from prospectively collected cases in all 45 stroke centres nationally. The thrombolytic rate was calculated from the total number of all ischemic strokes in the population of the Czech Republic since 2004. Results Thrombolytic rates of 1.3 (95%CI 1.1 to 1.4), 5.4 (95%CI 5.1 to 5.7), 13.6 (95%CI 13.1 to 14.0), 23.3 (95%CI 22.8 to 23.9), and 23.5% (95%CI 23.0 to 24.1%) were achieved in 2005, 2009, 2014, 2017, and 2018, respectively. National median door-to-needle times were 60-70 minutes before 2012 and then decreased progressively every year to 25 minutes (IQR 17 to 36) in 2018. In 2018, 33% of both university and non-university hospitals achieved median door-to-needle time <= 20 minutes. In 2018, door-to-needle times <= 20, <= 45, and <= 60 minutes were achieved in 39, 85, and 93% of patients. Discussion Thrombolysis can be provided to >= 20% of all ischemic strokes nationwide and it is realistic to achieve median door-to-needle time 20 minutes. Conclusion Stroke 20-20 could serve as national implementation target for intravenous thrombolysis and country specific implementation policies should be applied to achieve such target.
ER  -

MIKULÍK, Robert, Michal BAR, David CERNIK, Roman HERZIG, René JURA, Lubomir JURAK, Jiri NEUMANN, Daniel SANAK, Svatopluk OSTRY, Petr SEVCIK, Ondrej SKODA, David SKOLOUDIK, Daniel VACLAVIK a Ales TOMEK. Stroke 20 20: Implementation goals for intravenous thrombolysis. \textit{EUROPEAN STROKE JOURNAL}. LONDON: SAGE PUBLICATIONS LTD, 2021, roč.~6, č.~2, s.~151-159. ISSN~2396-9873. Dostupné z: https://dx.doi.org/10.1177/23969873211007684.

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