J 2021

Prevalence and Risk Factors of CoronaVac Side Effects: An Independent Cross-Sectional Study Among Healthcare Workers in Turkey

RIAD, Abanoub, Derya SAĞIROĞLU, Batuhan ÜSTÜN, Andrea POKORNÁ, Jitka KLUGAROVÁ et. al.

Základní údaje

Originální název

Prevalence and Risk Factors of CoronaVac Side Effects: An Independent Cross-Sectional Study Among Healthcare Workers in Turkey

Autoři

RIAD, Abanoub (818 Egypt, domácí), Derya SAĞIROĞLU, Batuhan ÜSTÜN, Andrea POKORNÁ (203 Česká republika, domácí), Jitka KLUGAROVÁ (203 Česká republika, domácí), Sameh ATTIA a Miloslav KLUGAR (203 Česká republika, domácí)

Vydání

Journal of Clinical Medicine, Basel, MDPI, 2021, 2077-0383

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30218 General and internal medicine

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 4.964

Kód RIV

RIV/00216224:14110/21:00121613

Organizační jednotka

Lékařská fakulta

DOI

UT WoS

000665884700001

Klíčová slova anglicky

COVID-19; drug-related side effects and adverse reactions; health personnel; mass vaccination; prevalence

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 18. 10. 2021 12:47, Mgr. Tereza Miškechová

Anotace

V originále

Background: COVIC-19 vaccine hesitancy is a serious threat to mass vaccination strategies that need to be accelerated currently for achieving a substantial level of community immunity. Independent (non-sponsored) studies have a great potential to enhance public confidence in vaccines and accelerate their uptake process. Methods: A nationwide cross-sectional study for the side effects (SE) of CoronaVac was carried out in February 2021 among Turkish healthcare workers who got recently vaccinated. The questionnaire inquired about local and systemic SEs that occurred in the short-term, within four weeks, following vaccination. Findings: A total of 780 healthcare workers were included in this study; 62.5% of them experienced at least one SE. Injection site pain (41.5%) was the most common local SE, while fatigue (23.6%), headache (18.7%), muscle pain (11.2%) and joint pain (5.9%) were the common systemic SE. Female healthcare workers (67.9%) were significantly more affected by local and systemic SEs than male colleagues (51.4%). Younger age, previous infection, and compromised health status (chronic illnesses and regular medicines uptake) can be associated with an increased risk of CoronaVac SEs. Interpretation: The independent research shows a higher prevalence of CoronaVac SEs than what is reported by phase 1 – 3 clinical trials. In general, the results of this study confirm the overall safety of CoronaVac and suggest potential risk factors for its SEs. Gender-based differences and SEs distribution among age groups are worth further investigation.

Návaznosti

LTC20031, projekt VaV
Název: Towards an International Network for Evidence-based Research in Clinical Health Research in the Czech Republic
Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Towards an International Network for Evidence-based Research in Clinical Health Research in the Czech Republic, INTER-COST
MUNI/A/1608/2020, interní kód MU
Název: Prohlubování znalostí v oblasti zdravotních rizik a benefitů výživy, prostředí a životního stylu III
Investor: Masarykova univerzita, Prohlubování znalostí v oblasti zdravotních rizik a benefitů výživy, prostředí a životního stylu III
MUNI/IGA/1543/2020, interní kód MU
Název: Evidence-based Practice of Healthcare Professionals and Students in the Czech Republic (Akronym: Evidence-Based Practice in Czechia)
Investor: Masarykova univerzita, Evidence-based Practice of Healthcare Professionals and Students in the Czech Republic