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@article{1769779,
author = {Riad, Abanoub and Sağıroğlu, Derya and Üstün, Batuhan and Pokorná, Andrea and Klugarová, Jitka and Attia, Sameh and Klugar, Miloslav},
article_location = {Basel},
article_number = {12},
doi = {http://dx.doi.org/10.3390/jcm10122629},
keywords = {COVID-19; drug-related side effects and adverse reactions; health personnel; mass vaccination; prevalence},
language = {eng},
issn = {2077-0383},
journal = {Journal of Clinical Medicine},
title = {Prevalence and Risk Factors of CoronaVac Side Effects: An Independent Cross-Sectional Study Among Healthcare Workers in Turkey},
url = {https://www.mdpi.com/2077-0383/10/12/2629},
volume = {10},
year = {2021}
}
TY - JOUR
ID - 1769779
AU - Riad, Abanoub - Sağıroğlu, Derya - Üstün, Batuhan - Pokorná, Andrea - Klugarová, Jitka - Attia, Sameh - Klugar, Miloslav
PY - 2021
TI - Prevalence and Risk Factors of CoronaVac Side Effects: An Independent Cross-Sectional Study Among Healthcare Workers in Turkey
JF - Journal of Clinical Medicine
VL - 10
IS - 12
SP - 1-13
EP - 1-13
PB - MDPI
SN - 20770383
KW - COVID-19
KW - drug-related side effects and adverse reactions
KW - health personnel
KW - mass vaccination
KW - prevalence
UR - https://www.mdpi.com/2077-0383/10/12/2629
N2 - Background: COVIC-19 vaccine hesitancy is a serious threat to mass vaccination strategies that need to be accelerated currently for achieving a substantial level of community immunity. Independent (non-sponsored) studies have a great potential to enhance public confidence in vaccines and accelerate their uptake process. Methods: A nationwide cross-sectional study for the side effects (SE) of CoronaVac was carried out in February 2021 among Turkish healthcare workers who got recently vaccinated. The questionnaire inquired about local and systemic SEs that occurred in the short-term, within four weeks, following vaccination. Findings: A total of 780 healthcare workers were included in this study; 62.5% of them experienced at least one SE. Injection site pain (41.5%) was the most common local SE, while fatigue (23.6%), headache (18.7%), muscle pain (11.2%) and joint pain (5.9%) were the common systemic SE. Female healthcare workers (67.9%) were significantly more affected by local and systemic SEs than male colleagues (51.4%). Younger age, previous infection, and compromised health status (chronic illnesses and regular medicines uptake) can be associated with an increased risk of CoronaVac SEs. Interpretation: The independent research shows a higher prevalence of CoronaVac SEs than what is reported by phase 1 – 3 clinical trials. In general, the results of this study confirm the overall safety of CoronaVac and suggest potential risk factors for its SEs. Gender-based differences and SEs distribution among age groups are worth further investigation.
ER -
RIAD, Abanoub, Derya SAĞIROĞLU, Batuhan ÜSTÜN, Andrea POKORNÁ, Jitka KLUGAROVÁ, Sameh ATTIA and Miloslav KLUGAR. Prevalence and Risk Factors of CoronaVac Side Effects: An Independent Cross-Sectional Study Among Healthcare Workers in Turkey. \textit{Journal of Clinical Medicine}. Basel: MDPI, 2021, vol.~10, No~12, p.~1-13. ISSN~2077-0383. Available from: https://dx.doi.org/10.3390/jcm10122629.
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