RADOCHA, Jakub, Tomas JELINEK, Luděk POUR, Ivan SPICKA, Jiri MINARIK, Tereza POPKOVA, Alexandra JUNGOVA, Petr PAVLICEK, Lucie BROŽOVÁ, Martin ŠTORK, Frantisek SEDLAK, Petra KRHOVSKA, Vladimir MAISNAR, Adriana HEINDORFER, Michal SYKORA, Marek WROBEL, Peter MIKULA, Petr KESSLER, Jana ULLRYCHOVA and Roman HAJEK. Urine immunofixation negativity is not necessary for complete response in intact immunoglobulin multiple myeloma: Retrospective real-world confirmation. International Journal of Laboratory Hematology. MALDEN: WILEY-BLACKWELL, 2021, vol. 43, No 5, p. "E244"-"E247", 4 pp. ISSN 1751-5521. Available from: https://dx.doi.org/10.1111/ijlh.13460.
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Basic information
Original name Urine immunofixation negativity is not necessary for complete response in intact immunoglobulin multiple myeloma: Retrospective real-world confirmation
Authors RADOCHA, Jakub (203 Czech Republic, guarantor), Tomas JELINEK (203 Czech Republic), Luděk POUR (203 Czech Republic, belonging to the institution), Ivan SPICKA (203 Czech Republic), Jiri MINARIK (203 Czech Republic), Tereza POPKOVA (203 Czech Republic), Alexandra JUNGOVA (203 Czech Republic), Petr PAVLICEK (203 Czech Republic), Lucie BROŽOVÁ (203 Czech Republic), Martin ŠTORK (203 Czech Republic, belonging to the institution), Frantisek SEDLAK (203 Czech Republic), Petra KRHOVSKA (203 Czech Republic), Vladimir MAISNAR (203 Czech Republic), Adriana HEINDORFER (203 Czech Republic), Michal SYKORA (203 Czech Republic), Marek WROBEL (203 Czech Republic), Peter MIKULA (203 Czech Republic), Petr KESSLER (203 Czech Republic), Jana ULLRYCHOVA (203 Czech Republic) and Roman HAJEK (203 Czech Republic).
Edition International Journal of Laboratory Hematology, MALDEN, WILEY-BLACKWELL, 2021, 1751-5521.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30205 Hematology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.450
RIV identification code RIV/00216224:14110/21:00121704
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1111/ijlh.13460
UT WoS 000607843000001
Keywords in English Urine immunofixation negativity; intact immunoglobulin multiple myeloma
Tags 14110212, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 7/12/2021 13:49.
Abstract
The definition of complete disease response (CR) in multiple myeloma (MM) continues to be reevaluated. The last widely accepted model of response assessment was proposed by the International Myeloma Working Group (IMWG) in 2016.1 Urine immunofixation (uIFE), one of the CR parameters, is being frequently omitted from CR evaluation in routine clinical practice. Patients with missing uIFE are then reported as having very good partial response (VGPR).2 It has been recently suggested in retrospective analysis by Lahuerta et al3 that patients with intact immunoglobulin myeloma (IIMM) who lack uIFE examination present with the very same prognosis as the patients with negative uIFE and therefore uIFE might not be necessary for CR definition in such patients.
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