Electrocardiographic parameters of left ventricular hypertrophy
and prediction of mortality in hemodialysis patients

J 2022

Electrocardiographic parameters of left ventricular hypertrophy and prediction of mortality in hemodialysis patients

BRAUNISCH, M. C., P. GUNDEL, S. WERFEL, C. C. MAYER, A. BAUER et. al.

Základní údaje

Originální název

Electrocardiographic parameters of left ventricular hypertrophy and prediction of mortality in hemodialysis patients

Autoři

BRAUNISCH, M. C. (garant), P. GUNDEL, S. WERFEL, C. C. MAYER, A. BAUER, B. HALLER, R. GUNTHNER, G. LORENZ, S. ANGERMANN, J. MATSCHKAL, C. SCHALLER, C. HOLZMANN-LITTIG, S. KEMMNER, J. MANN, A. KRIETER, L. RENDERS, S. WASSERTHEURER, G. SCHMIDT, U. HEEMANN, Marek MALÍK (203 Česká republika, domácí) a C. SCHMADERER

Vydání

JOURNAL OF NEPHROLOGY, HEIDELBERG, SPRINGER HEIDELBERG, 2022, 1121-8428

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30217 Urology and nephrology

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.400

Kód RIV

RIV/00216224:14110/22:00124939

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1007/s40620-021-01068-0

UT WoS

000652425000003

Klíčová slova anglicky

Left ventricular hypertrophy; Peguero-Lo presti; Cardiovascular mortality; Hemodialysis

Štítky

14110211, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 25. 2. 2022 10:00, Mgr. Tereza Miškechová

Anotace

V originále

Background In hemodialysis patients, left ventricular hypertrophy (LVH) contributes to high cardiovascular mortality. We examined cardiovascular mortality prediction by the recently proposed Peguero-Lo Presti voltage since it identifies more patients with electrocardiographic (ECG) LVH than Cornell or Sokolow-Lyon voltages. Methods A total of 308 patients on hemodialysis underwent 24 h ECG recordings. LVH parameters were measured before and after dialysis. The primary endpoint of cardiovascular mortality was recorded during a median 3-year follow up. Risk prediction was assessed by Cox regression, both unadjusted and adjusted for the Charlson Comorbidity Index and the Cardiovascular Mortality Risk Score. Results The Peguero-Lo Presti voltage identified with 21% the most patients with positive LVH criteria. All voltages significantly increased during dialysis. Factors such as ultrafiltration rate, Kt/V, body mass index, sex, and phosphate were the most relevant for these changes. During follow-up, 26 cardiovascular deaths occurred. Post-dialysis Peguero-Lo Presti cut-off as well as the Peguero-Lo Presti and Cornell voltages were independently associated with cardiovascular mortality in unadjusted and adjusted analysis. The Sokolow-Lyon voltage was not significantly associated with mortality. An optimal cut-off for the prediction of cardiovascular mortality was estimated at 1.38 mV for the Peguero-Lo Presti. Conclusions The post-dialysis Peguero-Lo Presti cut-off as well as the Peguero-Lo Presti and Cornell voltages allowed independent risk prediction of cardiovascular mortality in hemodialysis patients. Measuring the ECG LVH parameters after dialysis might allow a standardized interpretation as dialysis-specific factors influence the voltages.Y

Citovat

BRAUNISCH, M. C., P. GUNDEL, S. WERFEL, C. C. MAYER, A. BAUER, B. HALLER, R. GUNTHNER, G. LORENZ, S. ANGERMANN, J. MATSCHKAL, C. SCHALLER, C. HOLZMANN-LITTIG, S. KEMMNER, J. MANN, A. KRIETER, L. RENDERS, S. WASSERTHEURER, G. SCHMIDT, U. HEEMANN, Marek MALÍK a C. SCHMADERER. Electrocardiographic parameters of left ventricular hypertrophy and prediction of mortality in hemodialysis patients. JOURNAL OF NEPHROLOGY. HEIDELBERG: SPRINGER HEIDELBERG, 2022, roč. 35, č. 1, s. 233-244. ISSN 1121-8428. Dostupné z: https://dx.doi.org/10.1007/s40620-021-01068-0.

@article{1774637,
   author = {Braunisch, M. C. and Gundel, P. and Werfel, S. and Mayer, C. C. and Bauer, A. and Haller, B. and Gunthner, R. and Lorenz, G. and Angermann, S. and Matschkal, J. and Schaller, C. and HolzmannandLittig, C. and Kemmner, S. and Mann, J. and Krieter, A. and Renders, L. and Wassertheurer, S. and Schmidt, G. and Heemann, U. and Malík, Marek and Schmaderer, C.},
   article_location = {HEIDELBERG},
   article_number = {1},
   doi = {http://dx.doi.org/10.1007/s40620-021-01068-0},
   keywords = {Left ventricular hypertrophy; Peguero-Lo presti; Cardiovascular mortality; Hemodialysis},
   language = {eng},
   issn = {1121-8428},
   journal = {JOURNAL OF NEPHROLOGY},
   title = {Electrocardiographic parameters of left ventricular hypertrophy and prediction of mortality in hemodialysis patients},
   url = {https://link.springer.com/content/pdf/10.1007/s40620-021-01068-0.pdf},
   volume = {35},
   year = {2022}
}

TY  - JOUR
ID  - 1774637
AU  - Braunisch, M. C. - Gundel, P. - Werfel, S. - Mayer, C. C. - Bauer, A. - Haller, B. - Gunthner, R. - Lorenz, G. - Angermann, S. - Matschkal, J. - Schaller, C. - Holzmann-Littig, C. - Kemmner, S. - Mann, J. - Krieter, A. - Renders, L. - Wassertheurer, S. - Schmidt, G. - Heemann, U. - Malík, Marek - Schmaderer, C.
PY  - 2022
TI  - Electrocardiographic parameters of left ventricular hypertrophy and prediction of mortality in hemodialysis patients
JF  - JOURNAL OF NEPHROLOGY
VL  - 35
IS  - 1
SP  - 233-244
EP  - 233-244
PB  - SPRINGER HEIDELBERG
SN  - 11218428
KW  - Left ventricular hypertrophy
KW  - Peguero-Lo presti
KW  - Cardiovascular mortality
KW  - Hemodialysis
UR  - https://link.springer.com/content/pdf/10.1007/s40620-021-01068-0.pdf
N2  - Background In hemodialysis patients, left ventricular hypertrophy (LVH) contributes to high cardiovascular mortality. We examined cardiovascular mortality prediction by the recently proposed Peguero-Lo Presti voltage since it identifies more patients with electrocardiographic (ECG) LVH than Cornell or Sokolow-Lyon voltages. Methods A total of 308 patients on hemodialysis underwent 24 h ECG recordings. LVH parameters were measured before and after dialysis. The primary endpoint of cardiovascular mortality was recorded during a median 3-year follow up. Risk prediction was assessed by Cox regression, both unadjusted and adjusted for the Charlson Comorbidity Index and the Cardiovascular Mortality Risk Score. Results The Peguero-Lo Presti voltage identified with 21% the most patients with positive LVH criteria. All voltages significantly increased during dialysis. Factors such as ultrafiltration rate, Kt/V, body mass index, sex, and phosphate were the most relevant for these changes. During follow-up, 26 cardiovascular deaths occurred. Post-dialysis Peguero-Lo Presti cut-off as well as the Peguero-Lo Presti and Cornell voltages were independently associated with cardiovascular mortality in unadjusted and adjusted analysis. The Sokolow-Lyon voltage was not significantly associated with mortality. An optimal cut-off for the prediction of cardiovascular mortality was estimated at 1.38 mV for the Peguero-Lo Presti. Conclusions The post-dialysis Peguero-Lo Presti cut-off as well as the Peguero-Lo Presti and Cornell voltages allowed independent risk prediction of cardiovascular mortality in hemodialysis patients. Measuring the ECG LVH parameters after dialysis might allow a standardized interpretation as dialysis-specific factors influence the voltages.Y
ER  -

BRAUNISCH, M. C., P. GUNDEL, S. WERFEL, C. C. MAYER, A. BAUER, B. HALLER, R. GUNTHNER, G. LORENZ, S. ANGERMANN, J. MATSCHKAL, C. SCHALLER, C. HOLZMANN-LITTIG, S. KEMMNER, J. MANN, A. KRIETER, L. RENDERS, S. WASSERTHEURER, G. SCHMIDT, U. HEEMANN, Marek MALÍK a C. SCHMADERER. Electrocardiographic parameters of left ventricular hypertrophy and prediction of mortality in hemodialysis patients. \textit{JOURNAL OF NEPHROLOGY}. HEIDELBERG: SPRINGER HEIDELBERG, 2022, roč.~35, č.~1, s.~233-244. ISSN~1121-8428. Dostupné z: https://dx.doi.org/10.1007/s40620-021-01068-0.

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