In Comparison to Pathological Q Waves, Selvester Score Is a
Superior Diagnostic Indicator of Increased Long-Term Mortality
Risk in ST Elevation Myocardial Infarction Patients Treated
with Primary Coronary Intervention

J 2021

In Comparison to Pathological Q Waves, Selvester Score Is a Superior Diagnostic Indicator of Increased Long-Term Mortality Risk in ST Elevation Myocardial Infarction Patients Treated with Primary Coronary Intervention

HOLICKÁ, Mária; Pavla ČUČKOVÁ; Katerina HNATKOVA; Lumír KOC; Tomáš ONDRÚŠ et. al.

Basic information

Original name

In Comparison to Pathological Q Waves, Selvester Score Is a Superior Diagnostic Indicator of Increased Long-Term Mortality Risk in ST Elevation Myocardial Infarction Patients Treated with Primary Coronary Intervention

Authors

HOLICKÁ, Mária (703 Slovakia, belonging to the institution); Pavla ČUČKOVÁ (203 Czech Republic, belonging to the institution); Katerina HNATKOVA (203 Czech Republic); Lumír KOC (203 Czech Republic, belonging to the institution); Tomáš ONDRÚŠ (703 Slovakia, belonging to the institution); Petr LOKAJ (203 Czech Republic, belonging to the institution); Jiří PAŘENICA (203 Czech Republic, belonging to the institution); Tomáš NOVOTNÝ (203 Czech Republic, guarantor, belonging to the institution); Petr KALA (203 Czech Republic, belonging to the institution) and Marek MALÍK (203 Czech Republic, belonging to the institution)

Edition

Diagnostics, Basel, MDPI, 2021, 2075-4418

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

30218 General and internal medicine

Country of publisher

Switzerland

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Impact factor

Impact factor: 3.992

RIV identification code

RIV/00216224:14110/21:00121724

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.3390/diagnostics11050799

UT WoS

000653807800001

EID Scopus

2-s2.0-85106482606

Keywords in English

primary percutaneous coronary intervention; Q wave; Selvester score; ST elevation myocardial infarction

Abstract

In the original language

The development of pathological Q waves has long been correlated with worsened outcome in patients with ST elevation myocardial infarction (STEMI). In this study, we investigated long-term mortality of STEMI patients treated by primary percutaneous coronary intervention (PPCI) and compared predictive values of Q waves and of Selvester score for infarct volume estimation. Data of 283 consecutive STEMI patients (103 females) treated by PPCI were analysed. The presence of pathological Q wave was evaluated in pre-discharge electrocardiograms (ECGs) recorded >= 72 h after the chest pain onset (72 h Q). The Selvester score was evaluated in acute ECGs (acute Selvester score) and in the pre-discharge ECGs (72 h Selvester score). The results were related to total mortality and to clinical and laboratory variables. A 72 h Q presence and 72 h Selvester score >= 6 was observed in 184 (65.02%) and 143 (50.53%) patients, respectively. During a follow-up of 5.69 +/- 0.66 years, 36 (12.7%) patients died. Multivariably, 72 h Selvester score >= 6 was a strong independent predictor of death, while a predictive value of the 72 h Q wave was absent. In high-risk subpopulations defined by clinical and laboratory variables, the differences in total mortality were highly significant (p < 0.01 for all subgroups) when stratified by 72 h Selvester score >= 6. On the contrary, the additional risk-prediction by 72 h Q presence was either absent or only borderline. In contemporarily treated STEMI patients, Selvester score is a strong independent predictor of long-term all-cause mortality. On the contrary, the prognostic value of Q-wave presence appears limited in contemporarily treated STEMI patients.

Links

MUNI/A/1437/2020, interní kód MU

Name: Nevyřešené otázky a nové metody hodnocení elektrokardiografického signálu a struktur myokardu (Acronym: ECG2021)

Investor: Masaryk University

Cite

HOLICKÁ, Mária; Pavla ČUČKOVÁ; Katerina HNATKOVA; Lumír KOC; Tomáš ONDRÚŠ; Petr LOKAJ; Jiří PAŘENICA; Tomáš NOVOTNÝ; Petr KALA and Marek MALÍK. In Comparison to Pathological Q Waves, Selvester Score Is a Superior Diagnostic Indicator of Increased Long-Term Mortality Risk in ST Elevation Myocardial Infarction Patients Treated with Primary Coronary Intervention. Diagnostics. Basel: MDPI, 2021, vol. 11, No 5, p. 1-12. ISSN 2075-4418. Available from: https://dx.doi.org/10.3390/diagnostics11050799.

@article{1774638,
   author = {Holická, Mária and Čučková, Pavla and Hnatkova, Katerina and Koc, Lumír and Ondrúš, Tomáš and Lokaj, Petr and Pařenica, Jiří and Novotný, Tomáš and Kala, Petr and Malík, Marek},
   article_location = {Basel},
   article_number = {5},
   doi = {http://dx.doi.org/10.3390/diagnostics11050799},
   keywords = {primary percutaneous coronary intervention; Q wave; Selvester score; ST elevation myocardial infarction},
   language = {eng},
   issn = {2075-4418},
   journal = {Diagnostics},
   title = {In Comparison to Pathological Q Waves, Selvester Score Is a Superior Diagnostic Indicator of Increased Long-Term Mortality Risk in ST Elevation Myocardial Infarction Patients Treated with Primary Coronary Intervention},
   url = {https://www.mdpi.com/2075-4418/11/5/799},
   volume = {11},
   year = {2021}
}

TY  - JOUR
ID  - 1774638
AU  - Holická, Mária - Čučková, Pavla - Hnatkova, Katerina - Koc, Lumír - Ondrúš, Tomáš - Lokaj, Petr - Pařenica, Jiří - Novotný, Tomáš - Kala, Petr - Malík, Marek
PY  - 2021
TI  - In Comparison to Pathological Q Waves, Selvester Score Is a Superior Diagnostic Indicator of Increased Long-Term Mortality Risk in ST Elevation Myocardial Infarction Patients Treated with Primary Coronary Intervention
JF  - Diagnostics
VL  - 11
IS  - 5
SP  - 1-12
EP  - 1-12
PB  - MDPI
SN  - 20754418
KW  - primary percutaneous coronary intervention
KW  - Q wave
KW  - Selvester score
KW  - ST elevation myocardial infarction
UR  - https://www.mdpi.com/2075-4418/11/5/799
N2  - The development of pathological Q waves has long been correlated with worsened outcome in patients with ST elevation myocardial infarction (STEMI). In this study, we investigated long-term mortality of STEMI patients treated by primary percutaneous coronary intervention (PPCI) and compared predictive values of Q waves and of Selvester score for infarct volume estimation. Data of 283 consecutive STEMI patients (103 females) treated by PPCI were analysed. The presence of pathological Q wave was evaluated in pre-discharge electrocardiograms (ECGs) recorded >= 72 h after the chest pain onset (72 h Q). The Selvester score was evaluated in acute ECGs (acute Selvester score) and in the pre-discharge ECGs (72 h Selvester score). The results were related to total mortality and to clinical and laboratory variables. A 72 h Q presence and 72 h Selvester score >= 6 was observed in 184 (65.02%) and 143 (50.53%) patients, respectively. During a follow-up of 5.69 +/- 0.66 years, 36 (12.7%) patients died. Multivariably, 72 h Selvester score >= 6 was a strong independent predictor of death, while a predictive value of the 72 h Q wave was absent. In high-risk subpopulations defined by clinical and laboratory variables, the differences in total mortality were highly significant (p < 0.01 for all subgroups) when stratified by 72 h Selvester score >= 6. On the contrary, the additional risk-prediction by 72 h Q presence was either absent or only borderline. In contemporarily treated STEMI patients, Selvester score is a strong independent predictor of long-term all-cause mortality. On the contrary, the prognostic value of Q-wave presence appears limited in contemporarily treated STEMI patients.
ER  -

HOLICKÁ, Mária; Pavla ČUČKOVÁ; Katerina HNATKOVA; Lumír KOC; Tomáš ONDRÚŠ; Petr LOKAJ; Jiří PAŘENICA; Tomáš NOVOTNÝ; Petr KALA and Marek MALÍK. In Comparison to Pathological Q Waves, Selvester Score Is a Superior Diagnostic Indicator of Increased Long-Term Mortality Risk in ST Elevation Myocardial Infarction Patients Treated with Primary Coronary Intervention. \textit{Diagnostics}. Basel: MDPI, 2021, vol.~11, No~5, p.~1-12. ISSN~2075-4418. Available from: https://dx.doi.org/10.3390/diagnostics11050799.

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