LIPOVÝ, Břetislav, Filip RAŠKA, Iva KOCMANOVA, Marketa HANSLIANOVA, Martin HLADÍK, Jakub HOLOUBEK, Matěj BEZDÍČEK and Ctirad MACHÁČEK. Trichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantation. Journal of Fungi. BASEL: MDPI, 2021, vol. 7, No 6, p. 1-10. ISSN 2309-608X. Available from: https://dx.doi.org/10.3390/jof7060487.
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Basic information
Original name Trichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantation
Authors LIPOVÝ, Břetislav (203 Czech Republic, belonging to the institution), Filip RAŠKA (203 Czech Republic, belonging to the institution), Iva KOCMANOVA (203 Czech Republic), Marketa HANSLIANOVA (203 Czech Republic), Martin HLADÍK (703 Slovakia, guarantor, belonging to the institution), Jakub HOLOUBEK (203 Czech Republic, belonging to the institution), Matěj BEZDÍČEK (203 Czech Republic, belonging to the institution) and Ctirad MACHÁČEK (203 Czech Republic, belonging to the institution).
Edition Journal of Fungi, BASEL, MDPI, 2021, 2309-608X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10606 Microbiology
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 5.724
RIV identification code RIV/00216224:14110/21:00121943
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.3390/jof7060487
UT WoS 000666162500001
Keywords in English dermal substitute; infection; Trichoderma; Aspergillus; critical burns; liver transplantation; immunosuppression
Tags 14110212, 14110229, 14110230
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 19/7/2021 09:27.
Abstract
Infectious complications are responsible for the majority of mortalities and morbidities of patients with critical burns. Although bacteria are the predominant etiological agents in such patients, yeasts and fungi have become relatively common causes of infections over the last decade. Here, we report a case of a young man with critical burns on 88% TBSA (total body surface area) arising as a part of polytrauma. The patient's history of orthotopic liver transplantation associated with the patient's need to use combined immunosuppressant therapy was an additional complication. Due to deep burns in the forearm region, we have (after a suitable wound bed preparation) applied a new bi-layered dermal substitute. The patient, however, developed a combined fungal infection in the region of this dermal substitute caused by Trichoderma longibrachiatum and Aspergillus fischeri (the first case ever reported). The infection caused the loss of the split-thickness skin grafts (STSGs); we had to perform repeated hydrosurgical and mechanical debridement and a systemic antifungal treatment prior to re-application of the STSGs. The subsequent skin transplant was successful.
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