J 2021

Arterial Stiffness and Cardiometabolic-Based Chronic Disease: The Kardiovize Study

PAVLOVSKA, Iuliia, J. I. MECHANICK, G. A. M. NETO, M. M. INFANTE-GARCIA, R. NIETO-MARTINEZ et. al.

Základní údaje

Originální název

Arterial Stiffness and Cardiometabolic-Based Chronic Disease: The Kardiovize Study

Autoři

PAVLOVSKA, Iuliia (804 Ukrajina, garant, domácí), J. I. MECHANICK, G. A. M. NETO, M. M. INFANTE-GARCIA, R. NIETO-MARTINEZ, Šárka KUNZOVÁ (203 Česká republika), Anna POLCROVÁ (203 Česká republika, domácí), Robert VYSOKÝ (203 Česká republika, domácí), J. R. MEDINA-INOJOSA, F. LOPEZ-JIMENEZ, G. B. STOKIN a J. P. GONZALEZ-RIVAS

Vydání

Endocrine Practice, Jacksonville, American Association of Clinical Endocrinology, 2021, 1530-891X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30202 Endocrinology and metabolism

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 3.701

Kód RIV

RIV/00216224:14110/21:00121969

Organizační jednotka

Lékařská fakulta

UT WoS

000670046400007

Klíčová slova anglicky

adiposity; atherosclerosis; cardio-ankle vascular index; diabetes; obesity; type 2 diabetes

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 17. 5. 2022 10:20, Mgr. Tereza Miškechová

Anotace

V originále

Objective: Arterial stiffness (ArSt) describes a loss of arterial wall elasticity and is an independent predictor of cardiovascular events. A cardiometabolic-based chronic disease model integrates concepts of adiposity-based chronic disease (ABCD), dysglycemia-based chronic disease (DBCD), and cardiovascular disease. We assessed if ABCD and DBCD models detect more people with high ArSt compared with traditional adiposity and dysglycemia classifiers using the cardio-ankle vascular index (CAVI). Methods: We evaluated 2070 subjects aged 25 to 64 years from a random population-based sample. Those with type 1 diabetes were excluded. ABCD and DBCD were defined, and ArSt risk was stratified based on the American Association of Clinical Endocrinologists criteria. Results: The highest prevalence of a high CAVI was in stage 2 ABCD (18.5%) and stage 4 DBCD (31.8%), and the lowest prevalence was in stage 0 ABCD (2.2%). In univariate analysis, stage 2 ABCD and all DBCD stages increased the risk of having a high CAVI compared with traditional classifiers. After adjusting for age and gender, only an inverse association between obesity (body mass index >= 30 kg/m(2)) and CAVI remained significant. Nevertheless, body mass index was responsible for only 0.3% of CAVI variability. Conclusion: The ABCD and DBCD models showed better performance than traditional classifiers to detect subjects with ArSt; however, the variables were not independently associated with age and gender, which might be explained by the complexity and multifactoriality of the relationship of CAVI with the ABCD and DBCD models, mediated by insulin resistance. (C) 2021 AACE. Published by Elsevier Inc. All rights reserved.

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Arterial_Stiffness_and_Cardiometabolic-Based_Chronic_Disease_The_Kardiovize_Study.pdf
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