2021
Arterial Stiffness and Cardiometabolic-Based Chronic Disease: The Kardiovize Study
PAVLOVSKA, Iuliia, J. I. MECHANICK, G. A. M. NETO, M. M. INFANTE-GARCIA, R. NIETO-MARTINEZ et. al.Základní údaje
Originální název
Arterial Stiffness and Cardiometabolic-Based Chronic Disease: The Kardiovize Study
Autoři
PAVLOVSKA, Iuliia (804 Ukrajina, garant, domácí), J. I. MECHANICK, G. A. M. NETO, M. M. INFANTE-GARCIA, R. NIETO-MARTINEZ, Šárka KUNZOVÁ (203 Česká republika), Anna POLCROVÁ (203 Česká republika, domácí), Robert VYSOKÝ (203 Česká republika, domácí), J. R. MEDINA-INOJOSA, F. LOPEZ-JIMENEZ, G. B. STOKIN a J. P. GONZALEZ-RIVAS
Vydání
Endocrine Practice, Jacksonville, American Association of Clinical Endocrinology, 2021, 1530-891X
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30202 Endocrinology and metabolism
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 3.701
Kód RIV
RIV/00216224:14110/21:00121969
Organizační jednotka
Lékařská fakulta
UT WoS
000670046400007
Klíčová slova anglicky
adiposity; atherosclerosis; cardio-ankle vascular index; diabetes; obesity; type 2 diabetes
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 17. 5. 2022 10:20, Mgr. Tereza Miškechová
Anotace
V originále
Objective: Arterial stiffness (ArSt) describes a loss of arterial wall elasticity and is an independent predictor of cardiovascular events. A cardiometabolic-based chronic disease model integrates concepts of adiposity-based chronic disease (ABCD), dysglycemia-based chronic disease (DBCD), and cardiovascular disease. We assessed if ABCD and DBCD models detect more people with high ArSt compared with traditional adiposity and dysglycemia classifiers using the cardio-ankle vascular index (CAVI). Methods: We evaluated 2070 subjects aged 25 to 64 years from a random population-based sample. Those with type 1 diabetes were excluded. ABCD and DBCD were defined, and ArSt risk was stratified based on the American Association of Clinical Endocrinologists criteria. Results: The highest prevalence of a high CAVI was in stage 2 ABCD (18.5%) and stage 4 DBCD (31.8%), and the lowest prevalence was in stage 0 ABCD (2.2%). In univariate analysis, stage 2 ABCD and all DBCD stages increased the risk of having a high CAVI compared with traditional classifiers. After adjusting for age and gender, only an inverse association between obesity (body mass index >= 30 kg/m(2)) and CAVI remained significant. Nevertheless, body mass index was responsible for only 0.3% of CAVI variability. Conclusion: The ABCD and DBCD models showed better performance than traditional classifiers to detect subjects with ArSt; however, the variables were not independently associated with age and gender, which might be explained by the complexity and multifactoriality of the relationship of CAVI with the ABCD and DBCD models, mediated by insulin resistance. (C) 2021 AACE. Published by Elsevier Inc. All rights reserved.