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@article{1783530,
author = {Pavlovska, Iuliia and Mechanick, J. I. and Neto, G. A. M. and InfanteandGarcia, M. M. and NietoandMartinez, R. and Kunzová, Šárka and Polcrová, Anna and Vysoký, Robert and MedinaandInojosa, J. R. and LopezandJimenez, F. and Stokin, G. B. and GonzalezandRivas, J. P.},
article_location = {Jacksonville},
article_number = {6},
doi = {http://dx.doi.org/10.1016/j.eprac.2021.03.004},
keywords = {adiposity; atherosclerosis; cardio-ankle vascular index; diabetes; obesity; type 2 diabetes},
language = {eng},
issn = {1530-891X},
journal = {Endocrine Practice},
title = {Arterial Stiffness and Cardiometabolic-Based Chronic Disease: The Kardiovize Study},
url = {https://www.sciencedirect.com/science/article/pii/S1530891X21000859?via%3Dihub},
volume = {27},
year = {2021}
}
TY - JOUR
ID - 1783530
AU - Pavlovska, Iuliia - Mechanick, J. I. - Neto, G. A. M. - Infante-Garcia, M. M. - Nieto-Martinez, R. - Kunzová, Šárka - Polcrová, Anna - Vysoký, Robert - Medina-Inojosa, J. R. - Lopez-Jimenez, F. - Stokin, G. B. - Gonzalez-Rivas, J. P.
PY - 2021
TI - Arterial Stiffness and Cardiometabolic-Based Chronic Disease: The Kardiovize Study
JF - Endocrine Practice
VL - 27
IS - 6
SP - 571-578
EP - 571-578
PB - American Association of Clinical Endocrinology
SN - 1530891X
KW - adiposity
KW - atherosclerosis
KW - cardio-ankle vascular index
KW - diabetes
KW - obesity
KW - type 2 diabetes
UR - https://www.sciencedirect.com/science/article/pii/S1530891X21000859?via%3Dihub
N2 - Objective: Arterial stiffness (ArSt) describes a loss of arterial wall elasticity and is an independent predictor of cardiovascular events. A cardiometabolic-based chronic disease model integrates concepts of adiposity-based chronic disease (ABCD), dysglycemia-based chronic disease (DBCD), and cardiovascular disease. We assessed if ABCD and DBCD models detect more people with high ArSt compared with traditional adiposity and dysglycemia classifiers using the cardio-ankle vascular index (CAVI). Methods: We evaluated 2070 subjects aged 25 to 64 years from a random population-based sample. Those with type 1 diabetes were excluded. ABCD and DBCD were defined, and ArSt risk was stratified based on the American Association of Clinical Endocrinologists criteria. Results: The highest prevalence of a high CAVI was in stage 2 ABCD (18.5%) and stage 4 DBCD (31.8%), and the lowest prevalence was in stage 0 ABCD (2.2%). In univariate analysis, stage 2 ABCD and all DBCD stages increased the risk of having a high CAVI compared with traditional classifiers. After adjusting for age and gender, only an inverse association between obesity (body mass index >= 30 kg/m(2)) and CAVI remained significant. Nevertheless, body mass index was responsible for only 0.3% of CAVI variability. Conclusion: The ABCD and DBCD models showed better performance than traditional classifiers to detect subjects with ArSt; however, the variables were not independently associated with age and gender, which might be explained by the complexity and multifactoriality of the relationship of CAVI with the ABCD and DBCD models, mediated by insulin resistance. (C) 2021 AACE. Published by Elsevier Inc. All rights reserved.
ER -
PAVLOVSKA, Iuliia, J. I. MECHANICK, G. A. M. NETO, M. M. INFANTE-GARCIA, R. NIETO-MARTINEZ, Šárka KUNZOVÁ, Anna POLCROVÁ, Robert VYSOKÝ, J. R. MEDINA-INOJOSA, F. LOPEZ-JIMENEZ, G. B. STOKIN a J. P. GONZALEZ-RIVAS. Arterial Stiffness and Cardiometabolic-Based Chronic Disease: The Kardiovize Study. \textit{Endocrine Practice}. Jacksonville: American Association of Clinical Endocrinology, 2021, roč.~27, č.~6, s.~571-578. ISSN~1530-891X. Dostupné z: https://dx.doi.org/10.1016/j.eprac.2021.03.004.
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