2021
Expansion of rDNA and pericentromere satellite repeats in the genomes of bank voles Myodes glareolus exposed to environmental radionuclides
JERNFORS, Toni, John DANFORTH, Jenni KESANIEMI, Antom LAVRINIENKO, Eugene TUKALENKO et. al.Základní údaje
Originální název
Expansion of rDNA and pericentromere satellite repeats in the genomes of bank voles Myodes glareolus exposed to environmental radionuclides
Autoři
JERNFORS, Toni (246 Finsko), John DANFORTH (124 Kanada), Jenni KESANIEMI (246 Finsko), Antom LAVRINIENKO (246 Finsko), Eugene TUKALENKO (246 Finsko), Jiří FAJKUS (203 Česká republika, domácí), Martina DVOŘÁČKOVÁ (203 Česká republika, domácí), Täppio MAPPES (246 Finsko) a Phillip C. WATTS (826 Velká Británie a Severní Irsko)
Vydání
Ecology and Evolution, 111 River st, Hoboken 07030-5774, NJ USA, John Wiley & Sons, 2021, 2045-7758
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
10618 Ecology
Stát vydavatele
Velká Británie a Severní Irsko
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 3.167
Kód RIV
RIV/00216224:14740/21:00122007
Organizační jednotka
Středoevropský technologický institut
UT WoS
000653643300001
Klíčová slova anglicky
anthropogenic disturbance; chernobyl; copy number; ionizing radiation; myodes glareolus; rDNA
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 8. 10. 2024 09:55, Ing. Martina Blahová
Anotace
V originále
Altered copy number of certain highly repetitive regions of the genome, such as satellite DNA within heterochromatin and ribosomal RNA loci (rDNA), is hypothesized to help safeguard the genome against damage derived from external stressors. We quantified copy number of the 18S rDNA and a pericentromeric satellite DNA (Msat-160) in bank voles (Myodes glareolus) inhabiting the Chernobyl Exclusion Zone (CEZ), an area that is contaminated by radionuclides and where organisms are exposed to elevated levels of ionizing radiation. We found a significant increase in 18S rDNA and Msat-160 content in the genomes of bank voles from contaminated locations within the CEZ compared with animals from uncontaminated locations. Moreover, 18S rDNA and Msat-160 copy number were positively correlated in the genomes of bank voles from uncontaminated, but not in the genomes of animals inhabiting contaminated, areas. These results show the capacity for local-scale geographic variation in genome architecture and are consistent with the genomic safeguard hypothesis. Disruption of cellular processes related to genomic stability appears to be a hallmark effect in bank voles inhabiting areas contaminated by radionuclides.
Návaznosti
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