| GALUŠKA, David, Michaela JANÁKOVÁ, Beáta BEDNÁRIKOVÁ, Katarína CHALÁSOVÁ, Lukáš PÁCAL a Kateřina KAŇKOVÁ. Type 2 diabetes genetic risk score and morbidity and mortality associated with diabetic kidney disease. In 55th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD). 2019. ISSN 0012-186X. |
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@proceedings{1787359,
author = {Galuška, David and Janáková, Michaela and Bednáriková, Beáta and Chalásová, Katarína and Pácal, Lukáš and Kaňková, Kateřina},
booktitle = {55th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD)},
keywords = {Type 2 diabetes; genetic risk score; morbidity; mortality},
language = {eng},
title = {Type 2 diabetes genetic risk score and morbidity and mortality associated with diabetic kidney disease},
url = {https://link.springer.com/article/10.1007/s00125-019-4946-6},
year = {2019}
}
TY - CONF
ID - 1787359
AU - Galuška, David - Janáková, Michaela - Bednáriková, Beáta - Chalásová, Katarína - Pácal, Lukáš - Kaňková, Kateřina
PY - 2019
TI - Type 2 diabetes genetic risk score and morbidity and mortality associated with diabetic kidney disease
KW - Type 2 diabetes
KW - genetic risk score
KW - morbidity
KW - mortality
UR - https://link.springer.com/article/10.1007/s00125-019-4946-6
N2 - Diabetic kidney disease (DKD) is one of the most serious complications of type 2 diabetes mellitus (T2DM). Individual predisposition to development and progression of DKD has well established genetic component however it is still insufficiently explored. Genetic predisposition to T2DM is comprehensively described and genetic risk score (GRS) composed of 65 SNPs that is associated with 3-times higher risk of T2DM development has been established. In our study we tested the hypothesis that reduced GRS (comprised of 21 SNP with highest OR) might represent a risk factor for DKD progression and cardiovascular morbidity and mortality in T2DM patients in the Czech population.
ER -
GALUŠKA, David, Michaela JANÁKOVÁ, Beáta BEDNÁRIKOVÁ, Katarína CHALÁSOVÁ, Lukáš PÁCAL a Kateřina KAŇKOVÁ. Type 2 diabetes genetic risk score and morbidity and mortality associated with diabetic kidney disease. In \textit{55th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD)}. 2019. ISSN~0012-186X.
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