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@article{1788339, author = {Guida, Yago and de Carvalho, Gabriel Oliveira and Capella, Raquel and Pozo, Karla Andrea and Lino, Adan Santos and Azeredo, Antonio and Pena Carvalho, Daniele Fernandes and Ferreira Braga, Alfesio Luis and Machado Torres, Joao Paulo and Meire, Rodrigo Ornellas}, article_location = {OXFORD, OXON, ENGLAND}, article_number = {February 2021}, doi = {http://dx.doi.org/10.1016/j.envpol.2020.116359}, keywords = {Persistent organic pollutants; Chemical dumping sites; Environmental contamination; Outdoor air pollution; Human exposure; Risk assessment}, language = {eng}, issn = {0269-7491}, journal = {Environmental Pollution}, title = {Atmospheric Occurrence of Organochlorine Pesticides and Inhalation Cancer Risk in Urban Areas at Southeast Brazil}, url = {https://www.sciencedirect.com/science/article/abs/pii/S0269749120370482?via%3Dihub}, volume = {271}, year = {2021} }
TY - JOUR ID - 1788339 AU - Guida, Yago - de Carvalho, Gabriel Oliveira - Capella, Raquel - Pozo, Karla Andrea - Lino, Adan Santos - Azeredo, Antonio - Pena Carvalho, Daniele Fernandes - Ferreira Braga, Alfesio Luis - Machado Torres, Joao Paulo - Meire, Rodrigo Ornellas PY - 2021 TI - Atmospheric Occurrence of Organochlorine Pesticides and Inhalation Cancer Risk in Urban Areas at Southeast Brazil JF - Environmental Pollution VL - 271 IS - February 2021 SP - 1-14 EP - 1-14 PB - ELSEVIER SCI LTD SN - 02697491 KW - Persistent organic pollutants KW - Chemical dumping sites KW - Environmental contamination KW - Outdoor air pollution KW - Human exposure KW - Risk assessment UR - https://www.sciencedirect.com/science/article/abs/pii/S0269749120370482?via%3Dihub N2 - Organochlorine pesticides (OCPs) have been produced for almost a century and some of them are still used, even after they have been proved to be toxic, persistent, bioaccumulative and prone to long-range transport. Brazil has used and produced pesticides in industrial scales for both agricultural and public health purposes. Urban and industrial regions are of special concern due to their high population density and their increased exposure to chemical pollution, many times enhanced by chemical production, application or irregular dumping. Therefore, we aimed to investigate the occurrence of OCPs in outdoor air of urban sites from two major regions of southeast Brazil. Some of these sites have been affected by OCP production and their irregular dumping. Deterministic and probabilistic inhalation cancer risk (CR) assessments were conducted for the human populations exposed to OCPs in ambient air. Ambient air was mainly affected by Sigma-HCH (median = 340 pg m(-3)) and Sigma-DDT (median = 233 pg m(-3)), the only two OCPs registered for domissanitary purposes in Brazil. OCP concentrations tended to be higher in summer than in winter. Dumping sites resulted in the highest OCP atmospheric concentrations and, thus, in the highest CR estimations. Despite of all limitations, probabilistic simulations suggested that people living in the studied regions are exposed to an increased risk of hepatic cancer. Infants and toddlers (0 < 2 y) were exposed to the highest inhalation CRs compared to other age groups. Other exposure pathways (such as ingestion and dermic uptake) are needed for a more comprehensive risk assessment. Moreover, this study also highlights the need to review the human exposure to OCPs through inhalation and their respective CR in other impacted areas worldwide, especially where high levels of OCPs are still being measured. ER -
GUIDA, Yago, Gabriel Oliveira DE CARVALHO, Raquel CAPELLA, Karla Andrea POZO, Adan Santos LINO, Antonio AZEREDO, Daniele Fernandes PENA CARVALHO, Alfesio Luis FERREIRA BRAGA, Joao Paulo MACHADO TORRES a Rodrigo Ornellas MEIRE. Atmospheric Occurrence of Organochlorine Pesticides and Inhalation Cancer Risk in Urban Areas at Southeast Brazil. \textit{Environmental Pollution}. OXFORD, OXON, ENGLAND: ELSEVIER SCI LTD, 2021, roč.~271, February 2021, s.~1-14. ISSN~0269-7491. Dostupné z: https://dx.doi.org/10.1016/j.envpol.2020.116359.
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