Cognitive Aftereffects of Acute tDCS Coupled with Cognitive Training: An fMRI Study in Healthy Seniors.

ŠIMKO, Patrik, Monika PUPÍKOVÁ, Martin GAJDOŠ and Irena REKTOROVÁ. Cognitive Aftereffects of Acute tDCS Coupled with Cognitive Training: An fMRI Study in Healthy Seniors. Neural Plasticity. 2021, vol. 2021, APR, p. 6664479-6664488. ISSN 2090-5904. Available from: https://dx.doi.org/10.1155/2021/6664479.

Basic information

• Original name: Cognitive Aftereffects of Acute tDCS Coupled with Cognitive Training: An fMRI Study in Healthy Seniors.
• Authors: ŠIMKO, Patrik (703 Slovakia, belonging to the institution), Monika PUPÍKOVÁ (203 Czech Republic, belonging to the institution), Martin GAJDOŠ (203 Czech Republic, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, guarantor, belonging to the institution).
• Edition: Neural Plasticity, 2021, 2090-5904.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30103 Neurosciences
• Country of publisher: United Kingdom of Great Britain and Northern Ireland
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 3.144
• RIV identification code: RIV/00216224:14740/21:00120153
• Organization unit: Central European Institute of Technology
• Doi: http://dx.doi.org/10.1155/2021/6664479
• UT WoS: 000713168700001
• Keywords in English: DIRECT-CURRENT STIMULATION; WORKING-MEMORY; PREFRONTAL CORTEX; BRAIN-STIMULATION; IMPAIRMENT; ATTENTION; NETWORK; IMPROVE
• Tags: 14110127, CF MAFIL, podil, rivok
• Tags: International impact, Reviewed

Abstract

Enhancing cognitive functions through noninvasive brain stimulation is of enormous public interest, particularly for the aging population in whom processes such as working memory are known to decline. In a randomized double-blind crossover study, we investigated the acute behavioral and neural aftereffects of bifrontal and frontoparietal transcranial direct current stimulation (tDCS) combined with visual working memory (VWM) training on 25 highly educated older adults. Resting-state functional connectivity (rs-FC) analysis was performed prior to and after each stimulation session with a focus on the frontoparietal control network (FPCN). The bifrontal montage with anode over the left dorsolateral prefrontal cortex enhanced VWM accuracy as compared to the sham stimulation. With the rs-FC within the FPCN, we observed significant stimulationxtime interaction using bifrontal tDCS. We found no cognitive aftereffects of the frontoparietal tDCS compared to sham stimulation. Our study shows that a single bifrontal tDCS combined with cognitive training may enhance VWM performance and rs-FC within the relevant brain network even in highly educated older adults.

Links

• LM2018129, research and development project: Name: Národní infrastruktura pro biologické a medicínské zobrazování Czech-BioImaging

Investor: Ministry of Education, Youth and Sports of the CR

• NV18-04-00256, research and development project: Name: Efekt transkraniální stimulace tDCS na zrakovou pozornost u pacientů s mírnou kognitivní poruchou - studie kombinující MRI a neinvazivní mozkovou stimulaci

Investor: Ministry of Health of the CR