Predictors of Short- and Long-Term Mortality in Ischemic
Stroke: A Community-Based Study in Brno, Czech Republic

J 2022

Predictors of Short- and Long-Term Mortality in Ischemic Stroke: A Community-Based Study in Brno, Czech Republic

BRYNDZIAR, Tomáš, Dominika MATYSKOVÁ, Petra ŠEDOVÁ, Silvie BĚLAŠKOVÁ, Miroslav ZVOLSKÝ et. al.

Základní údaje

Originální název

Predictors of Short- and Long-Term Mortality in Ischemic Stroke: A Community-Based Study in Brno, Czech Republic

Autoři

BRYNDZIAR, Tomáš (703 Slovensko, domácí), Dominika MATYSKOVÁ (203 Česká republika, domácí), Petra ŠEDOVÁ (203 Česká republika, garant, domácí), Silvie BĚLAŠKOVÁ (203 Česká republika, domácí), Miroslav ZVOLSKÝ (203 Česká republika), Josef BEDNAŘÍK (203 Česká republika, domácí), Robert D. BROWN a Robert MIKULÍK (203 Česká republika, domácí)

Vydání

Cerebrovascular Diseases, Basel, S. Karger AG, 2022, 1015-9770

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.900

Kód RIV

RIV/00216224:14110/22:00125065

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1159/000519937

UT WoS

000721620800001

Klíčová slova anglicky

Czech Republic; Ischemic stroke; Mortality

Štítky

14110127, 14110212, 14110221, 14110313, podil

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 8. 2023 09:49, Mgr. Marie Šípková, DiS.

Anotace

V originále

Background and Objective: Short- and long-term mortality following ischemic stroke (IS) and their predictors have not been defined in the Czech population, and studies on long-term mortality are largely missing for the populations of Central Europe. Methods: Using the National Register of Hospitalized Patients and the Czech National Mortality Registry, we analyzed data on 1-month, 1-year, and 3-year all-cause mortality for patients admitted with IS to any of the 4 hospitals with a certified stroke unit in Brno, Czech Republic, in 2011. We reviewed discharge summaries and recorded potential factors impacting mortality after the index stroke event. Using univariate and multivariable analyses, we identified predictors of mortality at all 3 time points. Results: In our multivariable model, statin use (odds ratio [OR] 0.095, p < 0.0001), age at stroke (OR 1.03, p = 0.0445), and admission National Institutes of Health Stroke Scale (NIHSS) score (OR 1.16, p < 0.0001) predicted 1-month mortality, while statin use (OR 0.43, p = 0.0004), history of cardiac failure (OR 2.17, p = 0.0137), age at stroke (OR 1.07, p < 0.0001), and admission NIHSS score (OR 1.14, p < 0.0001) predicted 1-year mortality. Statin use (OR 0.54, p = 0.0051), history of cardiac failure (OR 2.13, p = 0.0206), age at stroke (OR 1.07, p < 0.0001), and admission NIHSS score (OR 1.11, p < 0.0001) also predicted 3-year mortality. Conclusions: Our study is the first to report data on short- and long-term mortality rates and their predictors in patients hospitalized with IS in the Czech population. Our results indicate that mortality rates and predictors of mortality are consistent with those reported in studies from other populations throughout the world.

Citovat

BRYNDZIAR, Tomáš, Dominika MATYSKOVÁ, Petra ŠEDOVÁ, Silvie BĚLAŠKOVÁ, Miroslav ZVOLSKÝ, Josef BEDNAŘÍK, Robert D. BROWN a Robert MIKULÍK. Predictors of Short- and Long-Term Mortality in Ischemic Stroke: A Community-Based Study in Brno, Czech Republic. Cerebrovascular Diseases. Basel: S. Karger AG, 2022, roč. 51, č. 3, s. 296-303. ISSN 1015-9770. Dostupné z: https://dx.doi.org/10.1159/000519937.

@article{1805223,
   author = {Bryndziar, Tomáš and Matysková, Dominika and Šedová, Petra and Bělašková, Silvie and Zvolský, Miroslav and Bednařík, Josef and Brown, Robert D. and Mikulík, Robert},
   article_location = {Basel},
   article_number = {3},
   doi = {http://dx.doi.org/10.1159/000519937},
   keywords = {Czech Republic; Ischemic stroke; Mortality},
   language = {eng},
   issn = {1015-9770},
   journal = {Cerebrovascular Diseases},
   note = {Korespondenční autor nereagoval na žádost o doplnění podílu. Podíl doplněn rovnocenně podle počtu participujících HS (dle rozhodnutí vedení PřF).},
   title = {Predictors of Short- and Long-Term Mortality in Ischemic Stroke: A Community-Based Study in Brno, Czech Republic},
   url = {https://www.karger.com/Article/FullText/519937},
   volume = {51},
   year = {2022}
}

TY  - JOUR
ID  - 1805223
AU  - Bryndziar, Tomáš - Matysková, Dominika - Šedová, Petra - Bělašková, Silvie - Zvolský, Miroslav - Bednařík, Josef - Brown, Robert D. - Mikulík, Robert
PY  - 2022
TI  - Predictors of Short- and Long-Term Mortality in Ischemic Stroke: A Community-Based Study in Brno, Czech Republic
JF  - Cerebrovascular Diseases
VL  - 51
IS  - 3
SP  - 296-303
EP  - 296-303
PB  - S. Karger AG
SN  - 10159770
N1  - Korespondenční autor nereagoval na žádost o doplnění podílu. Podíl doplněn rovnocenně podle počtu participujících HS (dle rozhodnutí vedení PřF).
KW  - Czech Republic
KW  - Ischemic stroke
KW  - Mortality
UR  - https://www.karger.com/Article/FullText/519937
N2  - Background and Objective: Short- and long-term mortality following ischemic stroke (IS) and their predictors have not been defined in the Czech population, and studies on long-term mortality are largely missing for the populations of Central Europe. Methods: Using the National Register of Hospitalized Patients and the Czech National Mortality Registry, we analyzed data on 1-month, 1-year, and 3-year all-cause mortality for patients admitted with IS to any of the 4 hospitals with a certified stroke unit in Brno, Czech Republic, in 2011. We reviewed discharge summaries and recorded potential factors impacting mortality after the index stroke event. Using univariate and multivariable analyses, we identified predictors of mortality at all 3 time points. Results: In our multivariable model, statin use (odds ratio [OR] 0.095, p < 0.0001), age at stroke (OR 1.03, p = 0.0445), and admission National Institutes of Health Stroke Scale (NIHSS) score (OR 1.16, p < 0.0001) predicted 1-month mortality, while statin use (OR 0.43, p = 0.0004), history of cardiac failure (OR 2.17, p = 0.0137), age at stroke (OR 1.07, p < 0.0001), and admission NIHSS score (OR 1.14, p < 0.0001) predicted 1-year mortality. Statin use (OR 0.54, p = 0.0051), history of cardiac failure (OR 2.13, p = 0.0206), age at stroke (OR 1.07, p < 0.0001), and admission NIHSS score (OR 1.11, p < 0.0001) also predicted 3-year mortality. Conclusions: Our study is the first to report data on short- and long-term mortality rates and their predictors in patients hospitalized with IS in the Czech population. Our results indicate that mortality rates and predictors of mortality are consistent with those reported in studies from other populations throughout the world.
ER  -

BRYNDZIAR, Tomáš, Dominika MATYSKOVÁ, Petra ŠEDOVÁ, Silvie BĚLAŠKOVÁ, Miroslav ZVOLSKÝ, Josef BEDNAŘÍK, Robert D. BROWN a Robert MIKULÍK. Predictors of Short- and Long-Term Mortality in Ischemic Stroke: A Community-Based Study in Brno, Czech Republic. \textit{Cerebrovascular Diseases}. Basel: S. Karger AG, 2022, roč.~51, č.~3, s.~296-303. ISSN~1015-9770. Dostupné z: https://dx.doi.org/10.1159/000519937.

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