Supramolecular hydrogelation via host-guest anion recognition:
Lamellar hydrogel materials for the release of cationic cargo

J 2021

Supramolecular hydrogelation via host-guest anion recognition: Lamellar hydrogel materials for the release of cationic cargo

KOKAN, Zoran, Miroslava DUSKOVA-SMRCKOVA a Vladimír ŠINDELÁŘ

Základní údaje

Originální název

Supramolecular hydrogelation via host-guest anion recognition: Lamellar hydrogel materials for the release of cationic cargo

Autoři

KOKAN, Zoran (191 Chorvatsko, domácí), Miroslava DUSKOVA-SMRCKOVA (203 Česká republika) a Vladimír ŠINDELÁŘ (203 Česká republika, garant, domácí)

Vydání

CHEM, CAMBRIDGE, CELL PRESS, 2021, 2451-9294

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10400 1.4 Chemical sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 25.832

Kód RIV

RIV/00216224:14310/21:00123019

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1016/j.chempr.2021.06.024

UT WoS

000695415900017

Klíčová slova anglicky

MOLECULAR-WEIGHT; GELS; WATER; POLYMER; BINDING; MACROCYCLE; BAMBUSURIL; RHEOLOGY; DELIVERY; GELATORS

Štítky

CF SAXS, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 11. 7. 2023 09:26, Mgr. Marie Šípková, DiS.

Anotace

V originále

Hydrogelation triggered by host-guest anion recognition is difficult to achieve due to the challenging anion recognition in water and de novo gelator design. Herein, we report such a hydrogel system, based on bambus[6]uril anion receptor, BU. Albeit not a gelator per se, BU formed hydrogels selectively in the presence of iodides or perchlorates. Anion recognition by BU governed the hydrogelation, indicated by the NMR, ATR-IR, and single-crystal X-ray. Gelation mechanism and lamellar nature of the network structure were elucidated by SAXS, cryoSEM, and holotomography methods. Rheological characterization revealed the hydrogels were stable and relatively strong. In physiological saline solutions, the hydrogels released cationic cargo by cation metathesis, leading to a gel-to-gel transformation. Choline derivatives, as model drugs, exhibited slow release from the hydrogels. Our simple hydrogel system may inspire the design of smart materials based on host-guest anion recognition, where the release or sequestration of specific charged species are desirable.

Návaznosti

EF16_027/0008360, projekt VaV

Název: Postdoc@MUNI

EF17_043/0009632, projekt VaV

Název: CETOCOEN Excellence

LM2018121, projekt VaV

Název: Výzkumná infrastruktura RECETOX (Akronym: RECETOX RI)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, RECETOX RI

LM2018127, projekt VaV

Název: Česká infrastruktura pro integrativní strukturní biologii (Akronym: CIISB)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Czech Infrastructure for Integrative Structural Biology

857560, interní kód MU
(Kód CEP: EF17_043/0009632)

Název: CETOCOEN Excellence (Akronym: CETOCOEN Excellence)

Investor: Evropská unie, CETOCOEN Excellence, Spreading excellence and widening participation

Citovat

KOKAN, Zoran, Miroslava DUSKOVA-SMRCKOVA a Vladimír ŠINDELÁŘ. Supramolecular hydrogelation via host-guest anion recognition: Lamellar hydrogel materials for the release of cationic cargo. CHEM. CAMBRIDGE: CELL PRESS, 2021, roč. 7, č. 9, s. 2473-2490. ISSN 2451-9294. Dostupné z: https://dx.doi.org/10.1016/j.chempr.2021.06.024.

@article{1805315,
   author = {Kokan, Zoran and DuskovaandSmrckova, Miroslava and Šindelář, Vladimír},
   article_location = {CAMBRIDGE},
   article_number = {9},
   doi = {http://dx.doi.org/10.1016/j.chempr.2021.06.024},
   keywords = {MOLECULAR-WEIGHT; GELS; WATER; POLYMER; BINDING; MACROCYCLE; BAMBUSURIL; RHEOLOGY; DELIVERY; GELATORS},
   language = {eng},
   issn = {2451-9294},
   journal = {CHEM},
   title = {Supramolecular hydrogelation via host-guest anion recognition: Lamellar hydrogel materials for the release of cationic cargo},
   url = {https://www.sciencedirect.com/science/article/abs/pii/S2451929421003569?via%3Dihub},
   volume = {7},
   year = {2021}
}

TY  - JOUR
ID  - 1805315
AU  - Kokan, Zoran - Duskova-Smrckova, Miroslava - Šindelář, Vladimír
PY  - 2021
TI  - Supramolecular hydrogelation via host-guest anion recognition: Lamellar hydrogel materials for the release of cationic cargo
JF  - CHEM
VL  - 7
IS  - 9
SP  - 2473-2490
EP  - 2473-2490
PB  - CELL PRESS
SN  - 24519294
KW  - MOLECULAR-WEIGHT
KW  - GELS
KW  - WATER
KW  - POLYMER
KW  - BINDING
KW  - MACROCYCLE
KW  - BAMBUSURIL
KW  - RHEOLOGY
KW  - DELIVERY
KW  - GELATORS
UR  - https://www.sciencedirect.com/science/article/abs/pii/S2451929421003569?via%3Dihub
N2  - Hydrogelation triggered by host-guest anion recognition is difficult to achieve due to the challenging anion recognition in water and de novo gelator design. Herein, we report such a hydrogel system, based on bambus[6]uril anion receptor, BU. Albeit not a gelator per se, BU formed hydrogels selectively in the presence of iodides or perchlorates. Anion recognition by BU governed the hydrogelation, indicated by the NMR, ATR-IR, and single-crystal X-ray. Gelation mechanism and lamellar nature of the network structure were elucidated by SAXS, cryoSEM, and holotomography methods. Rheological characterization revealed the hydrogels were stable and relatively strong. In physiological saline solutions, the hydrogels released cationic cargo by cation metathesis, leading to a gel-to-gel transformation. Choline derivatives, as model drugs, exhibited slow release from the hydrogels. Our simple hydrogel system may inspire the design of smart materials based on host-guest anion recognition, where the release or sequestration of specific charged species are desirable.
ER  -

KOKAN, Zoran, Miroslava DUSKOVA-SMRCKOVA a Vladimír ŠINDELÁŘ. Supramolecular hydrogelation via host-guest anion recognition: Lamellar hydrogel materials for the release of cationic cargo. \textit{CHEM}. CAMBRIDGE: CELL PRESS, 2021, roč.~7, č.~9, s.~2473-2490. ISSN~2451-9294. Dostupné z: https://dx.doi.org/10.1016/j.chempr.2021.06.024.

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