| ADÁMKOVÁ KRÁKOROVÁ, Dagmar, Jana HALÁMKOVÁ, Štěpán TUČEK, Ondřej BÍLEK, Jan KRISTEK, Tomáš KAZDA, Iva ZAMBO, Regina DEMLOVÁ a Igor KISS. Penis as a primary site of an extraskeletal Ewing sarcoma A case report. Medicine. Philadelphia: Lippincott Williams & Wilkins, 2021, roč. 100, č. 11, s. 1-5. ISSN 0025-7974. Dostupné z: https://dx.doi.org/10.1097/MD.0000000000025074. |
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@article{1807088,
author = {Adámková Krákorová, Dagmar and Halámková, Jana and Tuček, Štěpán and Bílek, Ondřej and Kristek, Jan and Kazda, Tomáš and Zambo, Iva and Demlová, Regina and Kiss, Igor},
article_location = {Philadelphia},
article_number = {11},
doi = {http://dx.doi.org/10.1097/MD.0000000000025074},
keywords = {extraskeletal Ewing sarcoma; multidisciplinary treatment; penis},
language = {eng},
issn = {0025-7974},
journal = {Medicine},
title = {Penis as a primary site of an extraskeletal Ewing sarcoma A case report},
url = {https://journals.lww.com/md-journal/Fulltext/2021/03190/Penis_as_a_primary_site_of_an_extraskeletal_Ewing.64.aspx},
volume = {100},
year = {2021}
}
TY - JOUR
ID - 1807088
AU - Adámková Krákorová, Dagmar - Halámková, Jana - Tuček, Štěpán - Bílek, Ondřej - Kristek, Jan - Kazda, Tomáš - Zambo, Iva - Demlová, Regina - Kiss, Igor
PY - 2021
TI - Penis as a primary site of an extraskeletal Ewing sarcoma A case report
JF - Medicine
VL - 100
IS - 11
SP - 1-5
EP - 1-5
PB - Lippincott Williams & Wilkins
SN - 00257974
KW - extraskeletal Ewing sarcoma
KW - multidisciplinary treatment
KW - penis
UR - https://journals.lww.com/md-journal/Fulltext/2021/03190/Penis_as_a_primary_site_of_an_extraskeletal_Ewing.64.aspx
N2 - Rationale: The Ewing sarcoma family of malignant tumors is a group of tumors characterized by morphologically similar round-cell neoplasms and by the presence of a common chromosomal translocation; Ewing sarcoma family of tumors typically occur in children and young adults between 4 to 15 years of age. The primary tumor usually originates in the bone, extraskeletal localization is rare. Patient concern: We present a case report concerning a 32-year-old male patient with a primary involvement of the penis. Diagnosis: The histopathology from the first penile biopsy showed a small-cell neuroendocrine carcinoma; however, that result was based on a sample obtained at a different facility than the Sarcoma Center, where the investigating pathologist did not have the adequate expertise. The patient then underwent a radical penectomy and a second reading of the histology was demanded after a radical penile amputation when Ewing sarcoma with R1 resection was confirmed. Interventions: The patient was referred to the national Sarcoma Center, where - using a multidisciplinary approach - the treatment was started with curative intent. However, it was preceded by a non-standard initiation of the therapy due to the poor primary diagnosis. Outcomes: The non-standard therapy at the onset of the disease caused a poor prognosis of an otherwise curable diagnosis. Despite all that, the patient survived for a relatively long time. Lessons: The treatment of sarcomas with atypical localizations should be conducted by an experienced multidisciplinary team in a center with experience in sarcoma treatment.
ER -
ADÁMKOVÁ KRÁKOROVÁ, Dagmar, Jana HALÁMKOVÁ, Štěpán TUČEK, Ondřej BÍLEK, Jan KRISTEK, Tomáš KAZDA, Iva ZAMBO, Regina DEMLOVÁ a Igor KISS. Penis as a primary site of an extraskeletal Ewing sarcoma A case report. \textit{Medicine}. Philadelphia: Lippincott Williams \&{} Wilkins, 2021, roč.~100, č.~11, s.~1-5. ISSN~0025-7974. Dostupné z: https://dx.doi.org/10.1097/MD.0000000000025074.
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