Hemodynamic and white blood cells parameters in patients with
first-episode psychosis: a pilot longitudinal study

J 2022

Hemodynamic and white blood cells parameters in patients with first-episode psychosis: a pilot longitudinal study

USTOHAL, Libor, Michaela MAYEROVÁ, Kateřina HORSKÁ, Marie OBDRŽÁLKOVÁ, Hana CRHOVÁ et. al.

Základní údaje

Originální název

Hemodynamic and white blood cells parameters in patients with first-episode psychosis: a pilot longitudinal study

Autoři

USTOHAL, Libor (203 Česká republika, domácí), Michaela MAYEROVÁ (203 Česká republika, domácí), Kateřina HORSKÁ (203 Česká republika, garant, domácí), Marie OBDRŽÁLKOVÁ (203 Česká republika, domácí), Hana CRHOVÁ (203 Česká republika, domácí), Hana PŘIKRYLOVÁ KUČEROVÁ (203 Česká republika, domácí), Eva ČEŠKOVÁ (203 Česká republika, domácí) a Tomáš KAŠPÁREK (203 Česká republika, domácí)

Vydání

International Journal of Psychiatry in Clinical Practice, ABINGDON, TAYLOR & FRANCIS LTD, 2022, 1365-1501

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30104 Pharmacology and pharmacy

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.000

Kód RIV

RIV/00216224:14160/22:00128993

Organizační jednotka

Farmaceutická fakulta

DOI

http://dx.doi.org/10.1080/13651501.2021.1962357

UT WoS

000683657200001

Klíčová slova anglicky

First-episode psychosis; mean arterial pressure; monocyte-to-lymphocyte ratio; neutrophil-to-lymphocyte ratio; pulse pressure; rate pressure product

Štítky

14110222, podil, rivok, ÚFTo

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 25. 4. 2023 14:50, Mgr. Michal Petr

Anotace

V originále

Objective Patients with schizophrenia are at higher risk of cardiovascular (CVS) related mortality. Close attention is being paid to the clinical utility of readily available CVS markers. Methods A pilot one-year longitudinal study in inpatients with first-episode psychosis (FEP) was carried out to determine markers of inflammation and endothelial dysfunction (monocyte- and neutrophil-to-lymphocyte ratios) and basal blood pressure, pulse, and derived hemodynamic parameters (PP: pulse pressure; RPP: rate pressure product; and MAP: mean arterial pressure). Results After one year, PP and RPP increased, as did systolic blood pressure and heart rate. Systolic blood pressure, PP, total white blood cells, and neutrophils correlated with weight gain. After one year, correlations between monocyte-to-lymphocyte ratio and RPP and MAP were observed. Conclusion Our study indicates worsening CVS health over the first year of treatment and emphasises the importance of early monitoring of CVS status using easily accessible parameters to prevent CVS-related mortality.

Citovat

USTOHAL, Libor, Michaela MAYEROVÁ, Kateřina HORSKÁ, Marie OBDRŽÁLKOVÁ, Hana CRHOVÁ, Hana PŘIKRYLOVÁ KUČEROVÁ, Eva ČEŠKOVÁ a Tomáš KAŠPÁREK. Hemodynamic and white blood cells parameters in patients with first-episode psychosis: a pilot longitudinal study. International Journal of Psychiatry in Clinical Practice. ABINGDON: TAYLOR & FRANCIS LTD, 2022, roč. 26, č. 2, s. 213-216. ISSN 1365-1501. Dostupné z: https://dx.doi.org/10.1080/13651501.2021.1962357.

@article{1808210,
   author = {Ustohal, Libor and Mayerová, Michaela and Horská, Kateřina and Obdržálková, Marie and Crhová, Hana and Přikrylová Kučerová, Hana and Češková, Eva and Kašpárek, Tomáš},
   article_location = {ABINGDON},
   article_number = {2},
   doi = {http://dx.doi.org/10.1080/13651501.2021.1962357},
   keywords = {First-episode psychosis; mean arterial pressure; monocyte-to-lymphocyte ratio; neutrophil-to-lymphocyte ratio; pulse pressure; rate pressure product},
   language = {eng},
   issn = {1365-1501},
   journal = {International Journal of Psychiatry in Clinical Practice},
   title = {Hemodynamic and white blood cells parameters in patients with first-episode psychosis: a pilot longitudinal study},
   url = {https://www.tandfonline.com/doi/abs/10.1080/13651501.2021.1962357?journalCode=ijpc20},
   volume = {26},
   year = {2022}
}

TY  - JOUR
ID  - 1808210
AU  - Ustohal, Libor - Mayerová, Michaela - Horská, Kateřina - Obdržálková, Marie - Crhová, Hana - Přikrylová Kučerová, Hana - Češková, Eva - Kašpárek, Tomáš
PY  - 2022
TI  - Hemodynamic and white blood cells parameters in patients with first-episode psychosis: a pilot longitudinal study
JF  - International Journal of Psychiatry in Clinical Practice
VL  - 26
IS  - 2
SP  - 213-216
EP  - 213-216
PB  - TAYLOR & FRANCIS LTD
SN  - 13651501
KW  - First-episode psychosis
KW  - mean arterial pressure
KW  - monocyte-to-lymphocyte ratio
KW  - neutrophil-to-lymphocyte ratio
KW  - pulse pressure
KW  - rate pressure product
UR  - https://www.tandfonline.com/doi/abs/10.1080/13651501.2021.1962357?journalCode=ijpc20
N2  - Objective Patients with schizophrenia are at higher risk of cardiovascular (CVS) related mortality. Close attention is being paid to the clinical utility of readily available CVS markers. Methods A pilot one-year longitudinal study in inpatients with first-episode psychosis (FEP) was carried out to determine markers of inflammation and endothelial dysfunction (monocyte- and neutrophil-to-lymphocyte ratios) and basal blood pressure, pulse, and derived hemodynamic parameters (PP: pulse pressure; RPP: rate pressure product; and MAP: mean arterial pressure). Results After one year, PP and RPP increased, as did systolic blood pressure and heart rate. Systolic blood pressure, PP, total white blood cells, and neutrophils correlated with weight gain. After one year, correlations between monocyte-to-lymphocyte ratio and RPP and MAP were observed. Conclusion Our study indicates worsening CVS health over the first year of treatment and emphasises the importance of early monitoring of CVS status using easily accessible parameters to prevent CVS-related mortality.
ER  -

USTOHAL, Libor, Michaela MAYEROVÁ, Kateřina HORSKÁ, Marie OBDRŽÁLKOVÁ, Hana CRHOVÁ, Hana PŘIKRYLOVÁ KUČEROVÁ, Eva ČEŠKOVÁ a Tomáš KAŠPÁREK. Hemodynamic and white blood cells parameters in patients with first-episode psychosis: a pilot longitudinal study. \textit{International Journal of Psychiatry in Clinical Practice}. ABINGDON: TAYLOR \&{} FRANCIS LTD, 2022, roč.~26, č.~2, s.~213-216. ISSN~1365-1501. Dostupné z: https://dx.doi.org/10.1080/13651501.2021.1962357.

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