2021
Health-related quality of life in women with autoimmune thyroid disease during pregnancy and postpartum: systematic review including 321,850 pregnancies
TUZIL, Jan, Jana BARTAKOVA, Torquil WATT a Tomáš DOLEŽALZákladní údaje
Originální název
Health-related quality of life in women with autoimmune thyroid disease during pregnancy and postpartum: systematic review including 321,850 pregnancies
Autoři
TUZIL, Jan (203 Česká republika, garant), Jana BARTAKOVA (203 Česká republika), Torquil WATT (208 Dánsko) a Tomáš DOLEŽAL (203 Česká republika, domácí)
Vydání
EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH, ABINGDON, TAYLOR & FRANCIS LTD, 2021, 1473-7167
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30104 Pharmacology and pharmacy
Stát vydavatele
Velká Británie a Severní Irsko
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 2.039
Kód RIV
RIV/00216224:14110/21:00123230
Organizační jednotka
Lékařská fakulta
UT WoS
000686823900001
Klíčová slova anglicky
Thyroid disease; pregnancy; postpartum; quality of life; depression; anxiety; utility; thyroid autoimmunity; thyroid disorder
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 13. 12. 2021 11:07, Mgr. Tereza Miškechová
Anotace
V originále
Background Utilities of the general population or expert estimates have been used for all published cost-effectiveness analyses of screening for thyroid disorders in pregnancy. Methods A systematic review CRD42019120897 of studies with patient-reported outcomes (PRO) and laboratory evidence of thyroid function/autoimmunity was conducted using PubMed, Cochrane Central, EconLit, SocIndex, DARE, NHS EEDS, Annual Reviews, and CINAHL. Quality was assessed using Joanna Briggs Institute appraisal tool. Results Of 664 abstracts screened, we analyzed 97 full texts. All studies describing the impact of thyroid disease on the generic QoL excluded pregnant and postpartum women. 21 reports of acceptable quality (321,850 pregnancies) determined depression and anxiety with validated tools and/or reported subjective symptoms. During pregnancy, contradictory conclusions were published on the impact of thyroid disease on PRO. Postpartum, antithyroid antibodies coincide with alexithymia and depression, postpartum thyroiditis negatively impacts mood. No conclusion could be drawn on the impact of thyroid hormonal levels. Conclusions The generic QoL in autoimmune thyroid disease during pregnancy has never been described, which represents an obstacle for the construction of economic models. We found contradictory information on the impact of thyroid disease on depression, anxiety, and specific symptoms.