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@article{1809417, author = {Tuzil, Jan and Bartakova, Jana and Watt, Torquil and Doležal, Tomáš}, article_location = {ABINGDON}, article_number = {6}, doi = {http://dx.doi.org/10.1080/14737167.2021.1941882}, keywords = {Thyroid disease; pregnancy; postpartum; quality of life; depression; anxiety; utility; thyroid autoimmunity; thyroid disorder}, language = {eng}, issn = {1473-7167}, journal = {EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH}, title = {Health-related quality of life in women with autoimmune thyroid disease during pregnancy and postpartum: systematic review including 321,850 pregnancies}, url = {https://www.tandfonline.com/doi/full/10.1080/14737167.2021.1941882}, volume = {21}, year = {2021} }
TY - JOUR ID - 1809417 AU - Tuzil, Jan - Bartakova, Jana - Watt, Torquil - Doležal, Tomáš PY - 2021 TI - Health-related quality of life in women with autoimmune thyroid disease during pregnancy and postpartum: systematic review including 321,850 pregnancies JF - EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH VL - 21 IS - 6 SP - 1179-1193 EP - 1179-1193 PB - TAYLOR & FRANCIS LTD SN - 14737167 KW - Thyroid disease KW - pregnancy KW - postpartum KW - quality of life KW - depression KW - anxiety KW - utility KW - thyroid autoimmunity KW - thyroid disorder UR - https://www.tandfonline.com/doi/full/10.1080/14737167.2021.1941882 N2 - Background Utilities of the general population or expert estimates have been used for all published cost-effectiveness analyses of screening for thyroid disorders in pregnancy. Methods A systematic review CRD42019120897 of studies with patient-reported outcomes (PRO) and laboratory evidence of thyroid function/autoimmunity was conducted using PubMed, Cochrane Central, EconLit, SocIndex, DARE, NHS EEDS, Annual Reviews, and CINAHL. Quality was assessed using Joanna Briggs Institute appraisal tool. Results Of 664 abstracts screened, we analyzed 97 full texts. All studies describing the impact of thyroid disease on the generic QoL excluded pregnant and postpartum women. 21 reports of acceptable quality (321,850 pregnancies) determined depression and anxiety with validated tools and/or reported subjective symptoms. During pregnancy, contradictory conclusions were published on the impact of thyroid disease on PRO. Postpartum, antithyroid antibodies coincide with alexithymia and depression, postpartum thyroiditis negatively impacts mood. No conclusion could be drawn on the impact of thyroid hormonal levels. Conclusions The generic QoL in autoimmune thyroid disease during pregnancy has never been described, which represents an obstacle for the construction of economic models. We found contradictory information on the impact of thyroid disease on depression, anxiety, and specific symptoms. ER -
TUZIL, Jan, Jana BARTAKOVA, Torquil WATT a Tomáš DOLEŽAL. Health-related quality of life in women with autoimmune thyroid disease during pregnancy and postpartum: systematic review including 321,850 pregnancies. \textit{EXPERT REVIEW OF PHARMACOECONOMICS \&{} OUTCOMES RESEARCH}. ABINGDON: TAYLOR \&{} FRANCIS LTD, 2021, roč.~21, č.~6, s.~1179-1193. ISSN~1473-7167. Dostupné z: https://dx.doi.org/10.1080/14737167.2021.1941882.
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