J 2021

Health-related quality of life in women with autoimmune thyroid disease during pregnancy and postpartum: systematic review including 321,850 pregnancies

TUZIL, Jan, Jana BARTAKOVA, Torquil WATT a Tomáš DOLEŽAL

Základní údaje

Originální název

Health-related quality of life in women with autoimmune thyroid disease during pregnancy and postpartum: systematic review including 321,850 pregnancies

Autoři

TUZIL, Jan (203 Česká republika, garant), Jana BARTAKOVA (203 Česká republika), Torquil WATT (208 Dánsko) a Tomáš DOLEŽAL (203 Česká republika, domácí)

Vydání

EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH, ABINGDON, TAYLOR & FRANCIS LTD, 2021, 1473-7167

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30104 Pharmacology and pharmacy

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 2.039

Kód RIV

RIV/00216224:14110/21:00123230

Organizační jednotka

Lékařská fakulta

UT WoS

000686823900001

Klíčová slova anglicky

Thyroid disease; pregnancy; postpartum; quality of life; depression; anxiety; utility; thyroid autoimmunity; thyroid disorder

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 13. 12. 2021 11:07, Mgr. Tereza Miškechová

Anotace

V originále

Background Utilities of the general population or expert estimates have been used for all published cost-effectiveness analyses of screening for thyroid disorders in pregnancy. Methods A systematic review CRD42019120897 of studies with patient-reported outcomes (PRO) and laboratory evidence of thyroid function/autoimmunity was conducted using PubMed, Cochrane Central, EconLit, SocIndex, DARE, NHS EEDS, Annual Reviews, and CINAHL. Quality was assessed using Joanna Briggs Institute appraisal tool. Results Of 664 abstracts screened, we analyzed 97 full texts. All studies describing the impact of thyroid disease on the generic QoL excluded pregnant and postpartum women. 21 reports of acceptable quality (321,850 pregnancies) determined depression and anxiety with validated tools and/or reported subjective symptoms. During pregnancy, contradictory conclusions were published on the impact of thyroid disease on PRO. Postpartum, antithyroid antibodies coincide with alexithymia and depression, postpartum thyroiditis negatively impacts mood. No conclusion could be drawn on the impact of thyroid hormonal levels. Conclusions The generic QoL in autoimmune thyroid disease during pregnancy has never been described, which represents an obstacle for the construction of economic models. We found contradictory information on the impact of thyroid disease on depression, anxiety, and specific symptoms.