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@article{1816727, author = {Deutschová, Barbora and Klimes, P. and Jordan, Z. and Jurak, P. and Eross, L. and Lamoš, Martin and Halamek, J. and Daniel, Pavel and Rektor, Ivan and Fabo, D.}, article_location = {Hoboken}, article_number = {5}, doi = {http://dx.doi.org/10.1111/epi.16883}, keywords = {anterior thalamic nucleus; deep brain stimulation; oscillations; prediction}, language = {eng}, issn = {0013-9580}, journal = {Epilepsia}, title = {Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus}, url = {https://onlinelibrary.wiley.com/doi/10.1111/epi.16883}, volume = {62}, year = {2021} }
TY - JOUR ID - 1816727 AU - Deutschová, Barbora - Klimes, P. - Jordan, Z. - Jurak, P. - Eross, L. - Lamoš, Martin - Halamek, J. - Daniel, Pavel - Rektor, Ivan - Fabo, D. PY - 2021 TI - Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus JF - Epilepsia VL - 62 IS - 5 SP - "E70"-"E75" EP - "E70"-"E75" PB - Wiley-Blackwell SN - 00139580 KW - anterior thalamic nucleus KW - deep brain stimulation KW - oscillations KW - prediction UR - https://onlinelibrary.wiley.com/doi/10.1111/epi.16883 N2 - We hypothesized that local/regional properties of stimulated structure/circuitry contribute to the effect of deep brain stimulation (DBS). We analyzed intracerebral electroencephalographic (EEG) recordings from externalized DBS electrodes targeted bilaterally in the anterior nuclei of the thalamus (ANT) in 12 patients (six responders, six nonresponders) with more than 1 year of follow-up care. In the bipolar local field potentials of the EEG, spectral power (PW) and power spectral entropy (PSE) were calculated in the passbands 1-4, 4-8, 8-12, 12-20, 20-45, 65-80, 80-200 and 200-500 Hz. The most significant differences between responders and nonresponders were observed in the BRIDGE area (bipolar recordings with one contact within the ANT and the second contact in adjacent tissue). In responders, PW was significantly decreased in the frequency bands of 65-80, 80-200, and 200-500 Hz (p < .05); PSE was significantly increased in all frequency bands (p < .05) except for 200-500 Hz (p = .06). The local EEG characteristics of ANT recorded after implantation may play a significant role in DBS response prediction. ER -
DEUTSCHOVÁ, Barbora, P. KLIMES, Z. JORDAN, P. JURAK, L. EROSS, Martin LAMOŠ, J. HALAMEK, Pavel DANIEL, Ivan REKTOR a D. FABO. Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus. \textit{Epilepsia}. Hoboken: Wiley-Blackwell, 2021, roč.~62, č.~5, s.~''E70''-''E75'', 6 s. ISSN~0013-9580. Dostupné z: https://dx.doi.org/10.1111/epi.16883.
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