Abietane diterpenes of the genus plectranthus sensu lato

J 2022

Abietane diterpenes of the genus plectranthus sensu lato

GÁBOROVÁ, Mária, Karel ŠMEJKAL a Renata KUBÍNOVÁ

Základní údaje

Originální název

Abietane diterpenes of the genus plectranthus sensu lato

Autoři

GÁBOROVÁ, Mária (703 Slovensko, garant, domácí), Karel ŠMEJKAL (203 Česká republika, domácí) a Renata KUBÍNOVÁ (203 Česká republika, domácí)

Vydání

Molecules, Basel, MDPI, 2022, 1420-3049

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30104 Pharmacology and pharmacy

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.600

Kód RIV

RIV/00216224:14160/22:00125323

Organizační jednotka

Farmaceutická fakulta

DOI

http://dx.doi.org/10.3390/molecules27010166

UT WoS

000748211400001

Klíčová slova anglicky

Abietane; Coleon; Diterpene; Hydroquinone; Lanugon; Plectranthus; Royleanone; Spirocoleon

Štítky

rivok, ÚPL

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 3. 2023 14:21, JUDr. Sabina Krejčiříková

Anotace

V originále

Plectranthus (Lamiaceae), which—according to the latest systematic revision—includes three separate genera (Coleus, Plectranthus sensu stricto, and Equilabium), is a genus widely used in traditional medicine—mainly in the treatment of various ailments of the digestive tract, respiratory tract, and skin. Many species of Plectranthus s.l. have been shown to produce phenolic compounds and terpenes. Diterpenes, especially those of the abietane class, are the most studied group of secondary metabolites found in Plectranthus s.l., which is characterized by a significant structural diversity arising from the oxygenation and further rearrangement of the basic tricyclic abietane skeleton to a complete aromatization of the ring system. This review summarizes the known information on abietane diterpenes, showing their structures, sources, and biosynthesis. A classification of these compounds into nine groups, according to the arrangement of their ring C, is used. Royleanones, spirocoleons, and hydroquinones are the largest classes of abietane diterpenes, covering more than 70% of all the compounds reviewed.

Návaznosti

MUNI/A/1688/2020, interní kód MU

Název: Izolace sekundárních metabolitů s potenciální biologickou aktivitou z rostlinných zdrojů (Akronym: Izolace sekundárních metabolitů)

Investor: Masarykova univerzita, Izolace sekundárních metabolitů s potenciální biologickou aktivitou z rostlinných zdrojů

Citovat

GÁBOROVÁ, Mária, Karel ŠMEJKAL a Renata KUBÍNOVÁ. Abietane diterpenes of the genus plectranthus sensu lato. Molecules. Basel: MDPI, 2022, roč. 27, č. 1, s. 1-64. ISSN 1420-3049. Dostupné z: https://dx.doi.org/10.3390/molecules27010166.

@article{1829958,
   author = {Gáborová, Mária and Šmejkal, Karel and Kubínová, Renata},
   article_location = {Basel},
   article_number = {1},
   doi = {http://dx.doi.org/10.3390/molecules27010166},
   keywords = {Abietane; Coleon; Diterpene; Hydroquinone; Lanugon; Plectranthus; Royleanone; Spirocoleon},
   language = {eng},
   issn = {1420-3049},
   journal = {Molecules},
   title = {Abietane diterpenes of the genus plectranthus sensu lato},
   url = {https://www.mdpi.com/1420-3049/27/1/166},
   volume = {27},
   year = {2022}
}

TY  - JOUR
ID  - 1829958
AU  - Gáborová, Mária - Šmejkal, Karel - Kubínová, Renata
PY  - 2022
TI  - Abietane diterpenes of the genus plectranthus sensu lato
JF  - Molecules
VL  - 27
IS  - 1
SP  - 1-64
EP  - 1-64
PB  - MDPI
SN  - 14203049
KW  - Abietane
KW  - Coleon
KW  - Diterpene
KW  - Hydroquinone
KW  - Lanugon
KW  - Plectranthus
KW  - Royleanone
KW  - Spirocoleon
UR  - https://www.mdpi.com/1420-3049/27/1/166
N2  - Plectranthus (Lamiaceae), which—according to the latest systematic revision—includes three separate genera (Coleus, Plectranthus sensu stricto, and Equilabium), is a genus widely used in traditional medicine—mainly in the treatment of various ailments of the digestive tract, respiratory tract, and skin. Many species of Plectranthus s.l. have been shown to produce phenolic compounds and terpenes. Diterpenes, especially those of the abietane class, are the most studied group of secondary metabolites found in Plectranthus s.l., which is characterized by a significant structural diversity arising from the oxygenation and further rearrangement of the basic tricyclic abietane skeleton to a complete aromatization of the ring system. This review summarizes the known information on abietane diterpenes, showing their structures, sources, and biosynthesis. A classification of these compounds into nine groups, according to the arrangement of their ring C, is used. Royleanones, spirocoleons, and hydroquinones are the largest classes of abietane diterpenes, covering more than 70% of all the compounds reviewed.
ER  -

GÁBOROVÁ, Mária, Karel ŠMEJKAL a Renata KUBÍNOVÁ. Abietane diterpenes of the genus plectranthus sensu lato. \textit{Molecules}. Basel: MDPI, 2022, roč.~27, č.~1, s.~1-64. ISSN~1420-3049. Dostupné z: https://dx.doi.org/10.3390/molecules27010166.

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