J 2021

Inverted Takotsubo Cardiomyopathy as an Early Complication After Liver Transplantation

BEDANOVA, Helena, Jiri ONDRASEK, Petr FILIPENSKÝ, Petr NEMEC, Petr DOBŠÁK et. al.

Základní údaje

Originální název

Inverted Takotsubo Cardiomyopathy as an Early Complication After Liver Transplantation

Autoři

BEDANOVA, Helena (203 Česká republika, garant), Jiri ONDRASEK (203 Česká republika), Petr FILIPENSKÝ (203 Česká republika, domácí), Petr NEMEC (203 Česká republika) a Petr DOBŠÁK (203 Česká republika, domácí)

Vydání

American Journal of Case Reports, Melville, INT SCIENTIFIC INFORMATION, INC, 2021, 1941-5923

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30218 General and internal medicine

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Kód RIV

RIV/00216224:14110/21:00124031

Organizační jednotka

Lékařská fakulta

UT WoS

000653065900001

Klíčová slova anglicky

Female; Liver Diseases Alcoholic; Stress Psychological; Takotsubo Cardiomyopathy

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 2. 2. 2022 14:07, Mgr. Tereza Miškechová

Anotace

V originále

Objective: Rare disease Background: Takotsubo cardiomyopathy (TTC) is a cardiac syndrome characterized by transient left ventricle (LV) dysfunction, typically showing apical ballooning due to apical akinesis with preserved basal segment contractility. The inverted form is very uncommon and is characterized by basal segment hypokinesis or akinesis and normal LV apical segment contractility. Case Report: We describe the case of a 49-year-old woman who developed inverted TTC after orthotopic liver transplantation. On day 1 (D1), dyspnea and oliguria suddenly appeared. A chest X-ray showed pulmonary edema, and echocardiography showed severe systolic LV dysfunction with an estimated ejection fraction of approximately 25% and akinesis of basal and midventricular LV segments, normal apical segment contractility, and mild mitral regurgitation. Elevated troponin T, creatine kinase-MB, and N-terminal pro B-type natriuretic peptide were found in the blood sample. Suspected inverted takotsubo cardiomyopathy was confirmed by left ventriculography, with normal apical part motion, akinesis in the other LV parts, and negative coronary angiography. The echocardiographic findings returned to normal on D14, and the patient was discharged from the hospital on D19 with normal LV motion and an ejection fraction of 65%. The transplanted liver function was excellent. Conclusions: Organ transplantation is connected with a great emotional stress because the patient's life depends on the death of another person. Therefore, we have to think about the possibility of stress cardiomyopathy even after liver transplantation, because early diagnosis and treatment can be life-saving for the patient. To our knowledge, this is the first described case of inverted takotsubo cardiomyopathy after liver transplantation.