The distribution of lagomorph syphilis caused by Treponema
paraluisleporidarum in Europe

J 2021

The distribution of lagomorph syphilis caused by Treponema paraluisleporidarum in Europe

HISGEN, L., L. ABEL, L. HALLMAIER-WACKER, S. LUERT, A. LAVAZZA et. al.

Základní údaje

Originální název

The distribution of lagomorph syphilis caused by Treponema paraluisleporidarum in Europe

Autoři

HISGEN, L., L. ABEL, L. HALLMAIER-WACKER, S. LUERT, A. LAVAZZA, T. TROGU, R. VELARDE, Markéta NOVÁKOVÁ (203 Česká republika, domácí), M. GYURANECZ, E. AGREN, A. BARLOW, David ŠMAJS (203 Česká republika, domácí) a S. KNAUF (garant)

Vydání

European Journal of Wildlife Research, NEW YORK, Springer, 2021, 1612-4642

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30303 Infectious Diseases

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.249

Kód RIV

RIV/00216224:14110/21:00119649

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1007/s10344-021-01535-w

UT WoS

000702654700001

Klíčová slova anglicky

Epidemiology; European brown hare; Rabbit; Mountain hare; Serology; Sexually transmitted disease

Štítky

14110513, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 15. 2. 2022 10:26, Mgr. Tereza Miškechová

Anotace

V originále

Treponema paraluisleporidarum infects both rabbits (ecovar Cuniculus) and hares (ecovar Lepus). While the occurrence of the bacterium has previously been reported for European brown hares (Lepus europaeus) and domestic rabbits (Oryctolagus cuniculus f. domestica), there are no data available that report infection in the European context. We tested a total of 1,995 serum samples and 287 genital swabs from opportunistically sampled European brown hares (Lepus europaeus; n = 2135), Mountain hares (Lepus timidus; n = 4), European rabbits (Oryctolagus cuniculus; n = 138), and pet rabbits (O. cuniculus f. domestica; n = 5). The samples originated from eight European countries. In case only serum was available, we tested the samples for the presence of anti-treponemal antibodies. For this, we utilized the Treponema pallidum-particle agglutination test (TP-PA), which is suited for the use in lagomorphs due to the antigenic cross-reactivity of anti-T. pallidum and anti-T. paraluisleporidarum antibodies. In addition, the results of 380 sera were confirmed using the fluorescent-Treponema antibody absorption test (FTA-ABS). In all cases where swab samples were available, DNA was extracted and tested using quantitative PCR to test for the presence of the lagomorph syphilis-bacterium. We were able to detect antibodies in 825 of 1,995 lagomorph sera (41.4%; brown hare: 825/1,868; rabbit: 0/127) and obtained positive qPCR results from 182 of 287 swab samples (63.4%; European brown hare: 167/267; mountain hare: 4/4; rabbit: 11/16). While all rabbit sera (n = 127) tested negative for anti-treponemal antibodies, the presence of the bacterium was confirmed in eight wild (n = 8/11) and three domestic rabbits (n = 3/5) from Germany using qPCR.

Návaznosti

GC18-23521J, projekt VaV

Název: Treponematózy u zástupců řádu zajícovci: genetická diverzita treponem a příbuznost s lidským patogenem T. pallidum

Investor: Grantová agentura ČR, Treponematózy u zástupců řádu zajícovci: genetická diverzita treponem a příbuznost s lidským patogenem T. pallidum

Citovat

HISGEN, L., L. ABEL, L. HALLMAIER-WACKER, S. LUERT, A. LAVAZZA, T. TROGU, R. VELARDE, Markéta NOVÁKOVÁ, M. GYURANECZ, E. AGREN, A. BARLOW, David ŠMAJS a S. KNAUF. The distribution of lagomorph syphilis caused by Treponema paraluisleporidarum in Europe. European Journal of Wildlife Research. NEW YORK: Springer, 2021, roč. 67, č. 5, s. 1-6. ISSN 1612-4642. Dostupné z: https://dx.doi.org/10.1007/s10344-021-01535-w.

@article{1834318,
   author = {Hisgen, L. and Abel, L. and HallmaierandWacker, L. and Luert, S. and Lavazza, A. and Trogu, T. and Velarde, R. and Nováková, Markéta and Gyuranecz, M. and Agren, E. and Barlow, A. and Šmajs, David and Knauf, S.},
   article_location = {NEW YORK},
   article_number = {5},
   doi = {http://dx.doi.org/10.1007/s10344-021-01535-w},
   keywords = {Epidemiology; European brown hare; Rabbit; Mountain hare; Serology; Sexually transmitted disease},
   language = {eng},
   issn = {1612-4642},
   journal = {European Journal of Wildlife Research},
   title = {The distribution of lagomorph syphilis caused by Treponema paraluisleporidarum in Europe},
   url = {https://link.springer.com/article/10.1007/s10344-021-01535-w},
   volume = {67},
   year = {2021}
}

TY  - JOUR
ID  - 1834318
AU  - Hisgen, L. - Abel, L. - Hallmaier-Wacker, L. - Luert, S. - Lavazza, A. - Trogu, T. - Velarde, R. - Nováková, Markéta - Gyuranecz, M. - Agren, E. - Barlow, A. - Šmajs, David - Knauf, S.
PY  - 2021
TI  - The distribution of lagomorph syphilis caused by Treponema paraluisleporidarum in Europe
JF  - European Journal of Wildlife Research
VL  - 67
IS  - 5
SP  - 1-6
EP  - 1-6
PB  - Springer
SN  - 16124642
KW  - Epidemiology
KW  - European brown hare
KW  - Rabbit
KW  - Mountain hare
KW  - Serology
KW  - Sexually transmitted disease
UR  - https://link.springer.com/article/10.1007/s10344-021-01535-w
N2  - Treponema paraluisleporidarum infects both rabbits (ecovar Cuniculus) and hares (ecovar Lepus). While the occurrence of the bacterium has previously been reported for European brown hares (Lepus europaeus) and domestic rabbits (Oryctolagus cuniculus f. domestica), there are no data available that report infection in the European context. We tested a total of 1,995 serum samples and 287 genital swabs from opportunistically sampled European brown hares (Lepus europaeus; n = 2135), Mountain hares (Lepus timidus; n = 4), European rabbits (Oryctolagus cuniculus; n = 138), and pet rabbits (O. cuniculus f. domestica; n = 5). The samples originated from eight European countries. In case only serum was available, we tested the samples for the presence of anti-treponemal antibodies. For this, we utilized the Treponema pallidum-particle agglutination test (TP-PA), which is suited for the use in lagomorphs due to the antigenic cross-reactivity of anti-T. pallidum and anti-T. paraluisleporidarum antibodies. In addition, the results of 380 sera were confirmed using the fluorescent-Treponema antibody absorption test (FTA-ABS). In all cases where swab samples were available, DNA was extracted and tested using quantitative PCR to test for the presence of the lagomorph syphilis-bacterium. We were able to detect antibodies in 825 of 1,995 lagomorph sera (41.4%; brown hare: 825/1,868; rabbit: 0/127) and obtained positive qPCR results from 182 of 287 swab samples (63.4%; European brown hare: 167/267; mountain hare: 4/4; rabbit: 11/16). While all rabbit sera (n = 127) tested negative for anti-treponemal antibodies, the presence of the bacterium was confirmed in eight wild (n = 8/11) and three domestic rabbits (n = 3/5) from Germany using qPCR.
ER  -

HISGEN, L., L. ABEL, L. HALLMAIER-WACKER, S. LUERT, A. LAVAZZA, T. TROGU, R. VELARDE, Markéta NOVÁKOVÁ, M. GYURANECZ, E. AGREN, A. BARLOW, David ŠMAJS a S. KNAUF. The distribution of lagomorph syphilis caused by Treponema paraluisleporidarum in Europe. \textit{European Journal of Wildlife Research}. NEW YORK: Springer, 2021, roč.~67, č.~5, s.~1-6. ISSN~1612-4642. Dostupné z: https://dx.doi.org/10.1007/s10344-021-01535-w.

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