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@article{1834562,
author = {TorresandMoreno, Carolina and PuenteandDelaCruz, Laura and Codling, Garry Paul and Villa, Aida L. and Cobo, Martha and Klánová, Jana and JohnsonandRestrepo, Boris},
article_location = {SAN DIEGO},
article_number = {March 2022},
doi = {http://dx.doi.org/10.1016/j.envres.2021.111981},
keywords = {Polycyclic aromatic hydrocarbons (PAHs); Human breast milk; Daily intake dose; Hazard quotient; Incremental lifetime cancer risk; Colombia},
language = {eng},
issn = {0013-9351},
journal = {Environmental Research},
title = {Polycyclic aromatic hydrocarbons (PAHs) in human breast milk from Colombia: Spatial occurrence, sources and probabilistic risk assessment},
url = {https://www.sciencedirect.com/science/article/pii/S0013935121012767?via%3Dihub},
volume = {204},
year = {2022}
}
TY - JOUR
ID - 1834562
AU - Torres-Moreno, Carolina - Puente-DelaCruz, Laura - Codling, Garry Paul - Villa, Aida L. - Cobo, Martha - Klánová, Jana - Johnson-Restrepo, Boris
PY - 2022
TI - Polycyclic aromatic hydrocarbons (PAHs) in human breast milk from Colombia: Spatial occurrence, sources and probabilistic risk assessment
JF - Environmental Research
VL - 204
IS - March 2022
SP - 1-8
EP - 1-8
PB - ACADEMIC PRESS INC ELSEVIER SCIENCE
SN - 00139351
KW - Polycyclic aromatic hydrocarbons (PAHs)
KW - Human breast milk
KW - Daily intake dose
KW - Hazard quotient
KW - Incremental lifetime cancer risk
KW - Colombia
UR - https://www.sciencedirect.com/science/article/pii/S0013935121012767?via%3Dihub
N2 - The diet is the main route that polycyclic aromatic hydrocarbons (PAHs) enter the body and measuring breast milk is one of the best ways to understand the maternal body burden and can be passed on to infants. In this study, it was determinate the concentrations of 23 PAHs in 60 milk samples taken from 3 cities in Colombia and to determine the potential routes of exposure and risk to human health. On average, concentration for the n-ary sumation PAHs across all locations was 186.6 ng g(-1), lipid mass (LM), with city means of 260.1, 175.7, and 123.9 ng g(-1) LM for Cartagena, Bogota and Medellin, respectively. Monte Carlo simulations were used to estimate the hazard quotient (HQ) and incremental lifetime cancer risk (ILCR) for infant dietary exposure to PAHs. HQs were below the safe thresholds (HQ = 1) while ILCRs were greater than the reference value equal to 10(-6) (mg kg(-1)day(-1)). Dietary source assessment indicated that fish is a significant source of PAHs, with mothers that consumed fish at least once per week having similar to 2.5 times greater PAH milk concentrations than other groups. While a disparity was also observed among consumers of exclusively marine (Sigma(PAHs) 198.5 ng g(-1) LM) or freshwater fish (Sigma(PAHs) 85.7 ng g(-1) LM). However, geographical considerations can be significant in this finding.
ER -
TORRES-MORENO, Carolina, Laura PUENTE-DELACRUZ, Garry Paul CODLING, Aida L. VILLA, Martha COBO, Jana KLÁNOVÁ a Boris JOHNSON-RESTREPO. Polycyclic aromatic hydrocarbons (PAHs) in human breast milk from Colombia: Spatial occurrence, sources and probabilistic risk assessment. \textit{Environmental Research}. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2022, roč.~204, March 2022, s.~1-8. ISSN~0013-9351. Dostupné z: https://dx.doi.org/10.1016/j.envres.2021.111981.
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