J 2023

Additive prognostic value of high baseline coronary flow velocity to ejection fraction during resting echocardiography: 3-year prospective study

ZAGATINA, A., O. GUSEVA, E. KALININA, F. RIGO, M. CAPRNDA et. al.

Základní údaje

Originální název

Additive prognostic value of high baseline coronary flow velocity to ejection fraction during resting echocardiography: 3-year prospective study

Autoři

ZAGATINA, A., O. GUSEVA, E. KALININA, F. RIGO, M. CAPRNDA, J. MASAN, K. GAZDIKOVA, P. FIRMENT, D. ULLRICH, L. GASPAR, Peter KRUŽLIAK (703 Slovensko, garant, domácí) a D. SHMATOV

Vydání

Acta Cardiologica, Leuven, Acta Cardiologica, 2023, 0001-5385

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 1.600 v roce 2022

Kód RIV

RIV/00216224:14110/23:00129951

Organizační jednotka

Lékařská fakulta

UT WoS

000738401800001

Klíčová slova anglicky

Coronary artery flow velocity; transthoracic echocardiography; coronary Doppler; coronary stenoses; cardiovascular prognosis

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 5. 4. 2024 07:26, Mgr. Tereza Miškechová

Anotace

V originále

Background There is a lack of information about the prognostic value of high velocity in coronary arteries during echocardiography. The present study was aimed at investigating the three-year prognostic value of coronary velocity assessment in all patients who were referred for echocardiography examination. Methods The prospective study comprises 747 consecutive patients. Death, myocardial infarction (MI), acute coronary syndrome (ACS), and/or revascularisation were defined as major adverse cardiac events (MACE). Routine echocardiography was added with coronary velocity assessment in the left main, anterior descending, or circumflex coronary arteries by the Doppler method. Results During a median follow-up of 36 months, 192 patients experienced MACE. Deaths occurred more frequently in patients with high local velocity in proximal left-sided segments vs. in middle left-sided segments vs. patients without high coronary velocity (9 vs. 3 vs. 1%, p < 0.0001). Death/MI/ACS occurred in 17 vs. 7 vs. 1%, p < 0.0001, respectively. Age (HR 1.04, 95% CI 1.00; 1.06; p < 0.04), a velocity more than 65 cm/s in any proximal segments of the arteries (HR 4.7, 95% CI 1.9; 11.9; p < 0.002), ejection fraction (HR 0.97, 95% CI 0.94; 0.99; p < 0.007) were strong independent prognostic predictors of death/MI/ACS. The maximal velocity of coronary flow velocity had a significant additive prognostic value to ejection fraction. Conclusions The coronary velocity parameters give long-term prognostic information that can be used to identify persons with a high risk of MACE in consecutive non-selected patients.