2023
Importance of evaluation of bone invasion type in squamous cell carcinomas of the oral cavity and oropharynx
PINK, Richard, Jaroslav MICHALEK, David KRAL, Michal MOZOLA, Pavel BENES et. al.Základní údaje
Originální název
Importance of evaluation of bone invasion type in squamous cell carcinomas of the oral cavity and oropharynx
Autoři
PINK, Richard (203 Česká republika), Jaroslav MICHALEK (203 Česká republika), David KRAL (203 Česká republika), Michal MOZOLA (203 Česká republika), Pavel BENES (203 Česká republika), Saskova LENKA (203 Česká republika) a Zdeněk DVOŘÁK (203 Česká republika, garant, domácí)
Vydání
Biomedical Papers, Olomouc: Palacky University, Olomouc, Palacky University, 2023, 1213-8118
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30208 Dentistry, oral surgery and medicine
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 0.900 v roce 2022
Kód RIV
RIV/00216224:14110/23:00129952
Organizační jednotka
Lékařská fakulta
UT WoS
000731344000001
Klíčová slova anglicky
oral squamous cell carcinoma of head and neck; neoplasm invasiveness; head and neck neoplasms; maxillofacial surgery; tumor grading; neoplasm staging; histocytochemistry
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 5. 9. 2023 09:26, Mgr. Tereza Miškechová
Anotace
V originále
Aims. The objective of this study was to compare bone invasion type with histopathological, clinical and immunohis Methods. The study included 49 patients who were treated for oral squamous cell carcinoma. Of which, 30 patients, with presence of bone invasion on histopathology, were divided according to the type of bone invasion (erosive, infiltrative, mixed). Each invasion type was compared to microvascular density using the CD34 marker. Results. The bone invasion was observed in 30 out of 49 patients (61.22%). On McNemar's test, statistically significant association was observed between bone invasion types and histopathological grade. In contrast, no significant correlation was observed between bone invasion type, and tumour volume or nodal metastases. In tumours with bone invasion of the infiltrative type, higher frequency of locoregional relapses was observed. The 5-year survival, since diagnosis, was approximately 60% in the erosive group, 40% in the mixed group, and merely 15% in the infiltrative group. Conclusion. Peritumoural microvascular density was not significantly related to bone invasion types. Whereas, a significantly higher intratumoural microvascular density was observed in infiltrative type of the bone invasion, when compared to the erosive and mixed type.