Thick nanoporous matrices of polystyrene nanoparticles and
their potential for electrochemical biosensing

J 2021

Thick nanoporous matrices of polystyrene nanoparticles and their potential for electrochemical biosensing

SOPOUŠEK, Jakub, Josef HUMLÍČEK, Antonín HLAVÁČEK, Veronika HORÁČKOVÁ, Petr SKLÁDAL et. al.

Základní údaje

Originální název

Thick nanoporous matrices of polystyrene nanoparticles and their potential for electrochemical biosensing

Autoři

SOPOUŠEK, Jakub (203 Česká republika), Josef HUMLÍČEK (203 Česká republika, domácí), Antonín HLAVÁČEK (203 Česká republika), Veronika HORÁČKOVÁ (203 Česká republika), Petr SKLÁDAL (203 Česká republika, domácí) a Karel LACINA (203 Česká republika, garant, domácí)

Vydání

Electrochimica Acta, OXFORD, Elsevier, 2021, 0013-4686

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10405 Electrochemistry

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 7.336

Kód RIV

RIV/00216224:14740/21:00119678

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1016/j.electacta.2020.137607

UT WoS

000609069000013

Klíčová slova anglicky

Nanopores; Nanoparticles; Multilayers; Thin film interference; Electrochemical impedance; Biosensing

Štítky

CF NANO, rivok

Změněno: 14. 10. 2024 12:33, Ing. Monika Szurmanová, Ph.D.

Anotace

V originále

Solid-state nanopores with diameter in units of nanometer can be formed by assembling spherical nanoparticles in a dense arrangement. In the current work, the properties of multi-layered highly ordered assemblies of polystyrene nanoparticles were studied, and their feasibility for electrochemical biosensing was probed. These thick matrices were built using a step-by-step deposition technique. Each individual layer of NPs exhibited distinct color which was caused by the thin film interference effect (a color of specific wavelength was characteristic for matrix of specific thickness). The electrochemical characteristics of matrices were investigated with impedance spectroscopy. The impedance spectra of multi-layered matrices exhibited formation of an additional semicircle (RC component additional to the one in a common Randles equivalent circuit). Further, model biosensing based on nanopore blocking was performed using human serum albumin as an antigen and the corresponding monoclonal antibody as an analyte (serology format). Resulting data disfavored the direct employment of the multi-layered matrices for biosensing purposes as the efficiency decreased with increasing thickness of matrices. However, the data revealed highly valuable information about the diffusion and redox processes in the thick nanoporous matrices. (C) 2020 Elsevier Ltd. All rights reserved.

Návaznosti

GJ19-16273Y, projekt VaV

Název: ROS-indukované uvolňování léčiv založené na interakcích ferocenylboronátů

Investor: Grantová agentura ČR, ROS-indukované uvolňování léčiv založené na interakcích ferocenylboronátů

LQ1601, projekt VaV

Název: CEITEC 2020 (Akronym: CEITEC2020)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, CEITEC 2020

90127, velká výzkumná infrastruktura

Název: CIISB II

Citovat

SOPOUŠEK, Jakub, Josef HUMLÍČEK, Antonín HLAVÁČEK, Veronika HORÁČKOVÁ, Petr SKLÁDAL a Karel LACINA. Thick nanoporous matrices of polystyrene nanoparticles and their potential for electrochemical biosensing. Electrochimica Acta. OXFORD: Elsevier, 2021, roč. 368, FEB, s. 137607-137615. ISSN 0013-4686. Dostupné z: https://dx.doi.org/10.1016/j.electacta.2020.137607.

@article{1838037,
   author = {Sopoušek, Jakub and Humlíček, Josef and Hlaváček, Antonín and Horáčková, Veronika and Skládal, Petr and Lacina, Karel},
   article_location = {OXFORD},
   article_number = {FEB},
   doi = {http://dx.doi.org/10.1016/j.electacta.2020.137607},
   keywords = {Nanopores; Nanoparticles; Multilayers; Thin film interference; Electrochemical impedance; Biosensing},
   language = {eng},
   issn = {0013-4686},
   journal = {Electrochimica Acta},
   title = {Thick nanoporous matrices of polystyrene nanoparticles and their potential for electrochemical biosensing},
   url = {https://www.sciencedirect.com/science/article/pii/S0013468620320004?via%3Dihub},
   volume = {368},
   year = {2021}
}

TY  - JOUR
ID  - 1838037
AU  - Sopoušek, Jakub - Humlíček, Josef - Hlaváček, Antonín - Horáčková, Veronika - Skládal, Petr - Lacina, Karel
PY  - 2021
TI  - Thick nanoporous matrices of polystyrene nanoparticles and their potential for electrochemical biosensing
JF  - Electrochimica Acta
VL  - 368
IS  - FEB
SP  - 137607
EP  - 137607
PB  - Elsevier
SN  - 00134686
KW  - Nanopores
KW  - Nanoparticles
KW  - Multilayers
KW  - Thin film interference
KW  - Electrochemical impedance
KW  - Biosensing
UR  - https://www.sciencedirect.com/science/article/pii/S0013468620320004?via%3Dihub
N2  - Solid-state nanopores with diameter in units of nanometer can be formed by assembling spherical nanoparticles in a dense arrangement. In the current work, the properties of multi-layered highly ordered assemblies of polystyrene nanoparticles were studied, and their feasibility for electrochemical biosensing was probed. These thick matrices were built using a step-by-step deposition technique. Each individual layer of NPs exhibited distinct color which was caused by the thin film interference effect (a color of specific wavelength was characteristic for matrix of specific thickness). The electrochemical characteristics of matrices were investigated with impedance spectroscopy. The impedance spectra of multi-layered matrices exhibited formation of an additional semicircle (RC component additional to the one in a common Randles equivalent circuit). Further, model biosensing based on nanopore blocking was performed using human serum albumin as an antigen and the corresponding monoclonal antibody as an analyte (serology format). Resulting data disfavored the direct employment of the multi-layered matrices for biosensing purposes as the efficiency decreased with increasing thickness of matrices. However, the data revealed highly valuable information about the diffusion and redox processes in the thick nanoporous matrices. (C) 2020 Elsevier Ltd. All rights reserved.
ER  -

SOPOUŠEK, Jakub, Josef HUMLÍČEK, Antonín HLAVÁČEK, Veronika HORÁČKOVÁ, Petr SKLÁDAL a Karel LACINA. Thick nanoporous matrices of polystyrene nanoparticles and their potential for electrochemical biosensing. \textit{Electrochimica Acta}. OXFORD: Elsevier, 2021, roč.~368, FEB, s.~137607-137615. ISSN~0013-4686. Dostupné z: https://dx.doi.org/10.1016/j.electacta.2020.137607.

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