SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES

P 2021

SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES

PARUCH, Kamil; Benoit Jean-Pierre CARBAIN; Štěpán HAVEL; Jiří DAMBORSKÝ; Jan BREZOVSKÝ et. al.

Základní údaje

Originální název

SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES

Autoři

PARUCH, Kamil; Benoit Jean-Pierre CARBAIN; Štěpán HAVEL; Jiří DAMBORSKÝ; Jan BREZOVSKÝ; Lukáš DANIEL; Alexandra SISÁKOVÁ; Fedor NIKULENKOV a Lumír KREJČÍ

Vydání

Číslo: EP3556755B1, Vydavatel: European Patent Office, Místo vydání: Mnichov, Název vlastníka: Masarykova Univerzita, 2021

Další údaje

Jazyk

angličtina

Typ výsledku

Patent

Obor

10401 Organic chemistry

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Kód RIV

RIV/00216224:14310/21:00124423

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

Antineoplastic agents; not condensed and containing further heterocyclic rings; condensed with carbocyclic rings; directly linked by a ring-member-to-ring-member bond; linked by a chain containing hetero atoms as chain links

Štítky

H22

Změněno: 23. 3. 2022 09:59, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

Citovat

PARUCH, Kamil; Benoit Jean-Pierre CARBAIN; Štěpán HAVEL; Jiří DAMBORSKÝ; Jan BREZOVSKÝ; Lukáš DANIEL; Alexandra SISÁKOVÁ; Fedor NIKULENKOV a Lumír KREJČÍ. SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES. 2021. Patent. Číslo: EP3556755B1. Vydavatel: European Patent Office. Místo vydání: Mnichov. Název vlastníka: Masarykova Univerzita. Datum registrace: 17. 4. 2018. Datum přijetí: 17. 11. 2021.

@misc{1842202,
   author = {Paruch, Kamil and Carbain, Benoit JeanandPierre and Havel, Štěpán and Damborský, Jiří and Brezovský, Jan and Daniel, Lukáš and Sisáková, Alexandra and Nikulenkov, Fedor and Krejčí, Lumír},
   keywords = {Antineoplastic agents; not condensed and containing further heterocyclic rings; condensed with carbocyclic rings; directly linked by a ring-member-to-ring-member bond; linked by a chain containing hetero atoms as chain links},
   language = {eng},
   title = {SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES},
   url = {https://worldwide.espacenet.com/patent/search?q=pn%3DEP3556755B1},
   year = {2021}
}

TY  - PAT
ID  - 1842202
AU  - Paruch, Kamil - Carbain, Benoit Jean-Pierre - Havel, Štěpán - Damborský, Jiří - Brezovský, Jan - Daniel, Lukáš - Sisáková, Alexandra - Nikulenkov, Fedor - Krejčí, Lumír
PY  - 2021
TI  - SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES
KW  - Antineoplastic agents
KW  - not condensed and containing further heterocyclic rings
KW  - condensed with carbocyclic rings
KW  - directly linked by a ring-member-to-ring-member bond
KW  - linked by a chain containing hetero atoms as chain links
UR  - https://worldwide.espacenet.com/patent/search?q=pn%3DEP3556755B1
N2  - The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
ER  -

PARUCH, Kamil; Benoit Jean-Pierre CARBAIN; Štěpán HAVEL; Jiří DAMBORSKÝ; Jan BREZOVSKÝ; Lukáš DANIEL; Alexandra SISÁKOVÁ; Fedor NIKULENKOV a Lumír KREJČÍ. \textit{SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES}. 2021. Patent. Číslo: EP3556755B1. Vydavatel: European Patent Office. Místo vydání: Mnichov. Název vlastníka: Masarykova Univerzita. Datum registrace: 17. 4. 2018. Datum přijetí: 17. 11. 2021.

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