MOHAMED, Sameh K., Brian WALSH, Mohan TIMILSINA, Maria TORRENTE, Fabio FRANCO, Mariano PROVENCIO, Adrianna JANIK, Luca COSTABELLO, Pasquale MINERVINI, Pontus STENETORP and Vít NOVÁČEK. On Predicting Recurrence in Early Stage Non-small Cell Lung Cancer. Online. In Adam B. Wilcox, Randi Foraker, Kensaku Kawamoto, Yves A. Lussier, Nadine McCleary. Proceedings of AMIA 2021 Annual Symposium. San Diego: AMIA, 2021, p. 853-862. ISSN 1942-597X.
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Basic information
Original name On Predicting Recurrence in Early Stage Non-small Cell Lung Cancer
Authors MOHAMED, Sameh K., Brian WALSH, Mohan TIMILSINA, Maria TORRENTE, Fabio FRANCO, Mariano PROVENCIO, Adrianna JANIK, Luca COSTABELLO, Pasquale MINERVINI, Pontus STENETORP and Vít NOVÁČEK (203 Czech Republic, guarantor, belonging to the institution).
Edition San Diego, Proceedings of AMIA 2021 Annual Symposium, p. 853-862, 10 pp. 2021.
Publisher AMIA
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 10201 Computer sciences, information science, bioinformatics
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Publication form electronic version available online
RIV identification code RIV/00216224:14330/21:00125683
Organization unit Faculty of Informatics
ISSN 1942-597X
Keywords in English machine learning; lung cancer; relapse prediction
Tags Artificial Intelligence, firank_A, machine learning, medical informatics, relapse prediction
Tags International impact, Reviewed
Changed by Changed by: doc. Mgr. Bc. Vít Nováček, PhD, učo 4049. Changed: 2/1/2023 10:10.
Abstract
Early detection and mitigation of disease recurrence in non-small cell lung cancer (NSCLC) patients is a nontrivial problem that is typically addressed either by rather generic follow-up screening guidelines, self-reporting, simple nomograms, or by models that predict relapse risk in individual patients using statistical analysis of retrospective data. We posit that machine learning models trained on patient data can provide an alternative approach that allows for more efficient development of many complementary models at once, superior accuracy, less dependency on the data collection protocols and increased support for explainability of the predictions. In this preliminary study, we describe an experimental suite of various machine learning models applied on a patient cohort of 2442 early stage NSCLC patients. We discuss the promising results achieved, as well as the lessons we learned while developing this baseline for further, more advanced studies in this area.
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