Bioaccessibility of PBDEs present in indoor dust: A novel
dialysis membrane method with a Tenax TA® absorption sink

J 2018

Bioaccessibility of PBDEs present in indoor dust: A novel dialysis membrane method with a Tenax TA® absorption sink

KADEMOGLOU, Aikaterini, Adrian C. WILLIAMS a Chris D. COLLINS

Základní údaje

Originální název

Bioaccessibility of PBDEs present in indoor dust: A novel dialysis membrane method with a Tenax TA® absorption sink

Autoři

KADEMOGLOU, Aikaterini (300 Řecko, garant, domácí), Adrian C. WILLIAMS a Chris D. COLLINS

Vydání

Science of The Total Environment, Elsevier B.V. 2018, 0048-9697

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 5.589

Kód RIV

RIV/00216224:14310/18:00124574

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1016/j.scitotenv.2017.11.097

UT WoS

000424196800001

Klíčová slova anglicky

Bioaccessibility; Tenax TA®; Dialysis membrane; PBDEs; Indoor dust

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 11. 5. 2022 15:09, Mgr. Marie Šípková, DiS.

Anotace

V originále

Human uptake of flame retardants (FRs) such as polybrominated diphenyl ethers (PBDEs) via indoor dust ingestion is commonly considered as 100% bioaccessible, leading to potential risk overestimation. Here, we present a novel in vitro colon-extended physiologically-based extraction test (CE-PBET) with Tenax TA® as an absorptive “sink” capable to enhance PBDE gut bioaccessibility. A cellulose-based dialysis membrane (MW cut-off 3.5 kDa) with high pH and temperature tolerance was used to encapsulate Tenax TA®, facilitating efficient physical separation between the absorbent and the dust, while minimizing re-absorption of the ingested PBDEs to the dust particles. As a proof of concept, PBDE-spiked indoor dust samples (n = 3) were tested under four different conditions; without any Tenax TA® addition (control) and with three different Tenax TA® loadings (i.e. 0.25, 0.5 or 0.75 g). Our results show that in order to maintain a constant sorptive gradient for the low MW PBDEs, 0.5 g of Tenax TA® are required in CE-PBET. Tenax TA® inclusion (0.5 g) resulted in 40% gut bioaccessibility for BDE153 and BDE183, whereas greater bioaccessibility values were seen for less hydrophobic PBDEs such as BDE28 and BDE47 (~ 60%). When tested using SRM 2585 (n = 3), our new Tenax TA® method did not present any statistically significant effect (p > 0.05) between non-spiked and PBDE-spiked SRM 2585 treatments. Our study describes an efficient method where due to the sophisticated design, Tenax TA® recovery and subsequent bioaccessibility determination can be simply and reliably achieved.

Citovat

KADEMOGLOU, Aikaterini, Adrian C. WILLIAMS a Chris D. COLLINS. Bioaccessibility of PBDEs present in indoor dust: A novel dialysis membrane method with a Tenax TA® absorption sink. Science of The Total Environment. Elsevier B.V., 2018, roč. 621, April 2018, s. 1-8. ISSN 0048-9697. Dostupné z: https://dx.doi.org/10.1016/j.scitotenv.2017.11.097.

@article{1852567,
   author = {Kademoglou, Aikaterini and Williams, Adrian C. and Collins, Chris D.},
   article_number = {April 2018},
   doi = {http://dx.doi.org/10.1016/j.scitotenv.2017.11.097},
   keywords = {Bioaccessibility; Tenax TA®; Dialysis membrane; PBDEs; Indoor dust},
   language = {eng},
   issn = {0048-9697},
   journal = {Science of The Total Environment},
   title = {Bioaccessibility of PBDEs present in indoor dust: A novel dialysis membrane method with a Tenax TA® absorption sink},
   url = {https://www.sciencedirect.com/science/article/pii/S0048969717331558?via%3Dihub},
   volume = {621},
   year = {2018}
}

TY  - JOUR
ID  - 1852567
AU  - Kademoglou, Aikaterini - Williams, Adrian C. - Collins, Chris D.
PY  - 2018
TI  - Bioaccessibility of PBDEs present in indoor dust: A novel dialysis membrane method with a Tenax TA® absorption sink
JF  - Science of The Total Environment
VL  - 621
IS  - April 2018
SP  - 1-8
EP  - 1-8
PB  - Elsevier B.V.
SN  - 00489697
KW  - Bioaccessibility
KW  - Tenax TA®
KW  - Dialysis membrane
KW  - PBDEs
KW  - Indoor dust
UR  - https://www.sciencedirect.com/science/article/pii/S0048969717331558?via%3Dihub
N2  - Human uptake of flame retardants (FRs) such as polybrominated diphenyl ethers (PBDEs) via indoor dust ingestion is commonly considered as 100% bioaccessible, leading to potential risk overestimation. Here, we present a novel in vitro colon-extended physiologically-based extraction test (CE-PBET) with Tenax TA® as an absorptive “sink” capable to enhance PBDE gut bioaccessibility. A cellulose-based dialysis membrane (MW cut-off 3.5 kDa) with high pH and temperature tolerance was used to encapsulate Tenax TA®, facilitating efficient physical separation between the absorbent and the dust, while minimizing re-absorption of the ingested PBDEs to the dust particles. As a proof of concept, PBDE-spiked indoor dust samples (n = 3) were tested under four different conditions; without any Tenax TA® addition (control) and with three different Tenax TA® loadings (i.e. 0.25, 0.5 or 0.75 g). Our results show that in order to maintain a constant sorptive gradient for the low MW PBDEs, 0.5 g of Tenax TA® are required in CE-PBET. Tenax TA® inclusion (0.5 g) resulted in 40% gut bioaccessibility for BDE153 and BDE183, whereas greater bioaccessibility values were seen for less hydrophobic PBDEs such as BDE28 and BDE47 (~ 60%). When tested using SRM 2585 (n = 3), our new Tenax TA® method did not present any statistically significant effect (p > 0.05) between non-spiked and PBDE-spiked SRM 2585 treatments. Our study describes an efficient method where due to the sophisticated design, Tenax TA® recovery and subsequent bioaccessibility determination can be simply and reliably achieved.
ER  -

KADEMOGLOU, Aikaterini, Adrian C. WILLIAMS a Chris D. COLLINS. Bioaccessibility of PBDEs present in indoor dust: A novel dialysis membrane method with a Tenax TA® absorption sink. \textit{Science of The Total Environment}. Elsevier B.V., 2018, roč.~621, April 2018, s.~1-8. ISSN~0048-9697. Dostupné z: https://dx.doi.org/10.1016/j.scitotenv.2017.11.097.

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