C 2017

POC in biowarfare detection and defence applications: an update

SKLÁDAL, Petr

Basic information

Original name

POC in biowarfare detection and defence applications: an update

Authors

SKLÁDAL, Petr (203 Czech Republic, guarantor, belonging to the institution)

Edition

3. vyd. England, Portable Biosensors and Point-of-Care Systems, p. 209-230, 22 pp. IET Healthcare Technologies Series, 2017

Publisher

Institution of Engineering and Technology

Other information

Language

English

Type of outcome

Chapter(s) of a specialized book

Field of Study

10608 Biochemistry and molecular biology

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

is not subject to a state or trade secret

Publication form

printed version "print"

References:

Organization unit

Faculty of Science

ISBN

978-1-84919-962-9

UT WoS

000780026100012

EID Scopus

2-s2.0-85116998665

Keywords in English

immunochemical devices; point-of-care; viruses; bacteria; ELISA; antibodies; biowarfare detection; bioagents; immunosensors; polymerase chain reaction; affinity based recognition systems

Tags

International impact, Reviewed
Changed: 27/8/2025 08:36, Mgr. Marie Novosadová Šípková, DiS.

Abstract

In the original language

For bacteria and viruses as bioagents, various types of immunochemical devices are preferred for the early response and good sensitivity; the capability of continuous monitoring is also a quite attractive advantage. The detection occurs on the phenotype level, and no extraction of the genetic material from the bioagent is required, which is the necessary case for methods based on PCR and general detection of specific nucleic acid sequences. ELISA as a classic immunoanalytical format inspired various types of immunosensors. Here, the optical [10] and electrochemical [11] immunosensors will be addressed as the approach combining high sensitivity, simple construction and portability of the sensing part with the excellent specificity of antibodies and other affinity-based recognition systems.