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@article{1854522, author = {Cocco, P. and Satta, G. and Meloni, F. and Pilia, I. and Ahmed, F. and Becker, N. and Casabonne, D. and de Sanjosé, S. and Foretová, Lenka and Maynadié, M. and Nieters, A. and Staines, A. and t'Mannetje, A. and Zucca, M. and Ennas, M. G. and Campagna, M. and De Matteis, S. and Benavente, Y.}, article_location = {HELSINKI}, article_number = {1}, doi = {http://dx.doi.org/10.5271/sjweh.3925}, keywords = {B cell lymphoma; epidemiology; flour dust; Hodgkin lymphoma; leather dust; textile dust; wood dust}, language = {eng}, issn = {0355-3140}, journal = {SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH}, title = {Occupational exposure to organic dust and risk of lymphoma subtypes in the EPILYMPH case-control study}, url = {https://www.sjweh.fi/show_abstract.php?abstract_id=3925}, volume = {47}, year = {2021} }
TY - JOUR ID - 1854522 AU - Cocco, P. - Satta, G. - Meloni, F. - Pilia, I. - Ahmed, F. - Becker, N. - Casabonne, D. - de Sanjosé, S. - Foretová, Lenka - Maynadié, M. - Nieters, A. - Staines, A. - t'Mannetje, A. - Zucca, M. - Ennas, M. G. - Campagna, M. - De Matteis, S. - Benavente, Y. PY - 2021 TI - Occupational exposure to organic dust and risk of lymphoma subtypes in the EPILYMPH case-control study JF - SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH VL - 47 IS - 1 SP - 42-51 EP - 42-51 PB - SCANDINAVIAN JOURNAL WORK ENVIRONMENT & HEALTH SN - 03553140 KW - B cell lymphoma KW - epidemiology KW - flour dust KW - Hodgkin lymphoma KW - leather dust KW - textile dust KW - wood dust UR - https://www.sjweh.fi/show_abstract.php?abstract_id=3925 N2 - Objectives This study aimed to estimate the risk of lymphoma and its major subtypes in relation to occupational exposure to specific organic dusts. Methods We explored the association in 1853 cases and 1997 controls who participated in the EpiLymph case-control study, conducted in six European countries in 1998-2004. Based on expert assessment of lifetime occupational exposures, we calculated the risk of the major lymphoma subtypes associated with exposure to six specific organic dusts, namely, flour, hardwood, softwood, natural textile, synthetic textile, and leather, and two generic (any types) groups: wood and textile dusts. Risk was predicted with unconditional regression modeling, adjusted by age, gender, study center, and education. Results We observed a 2.1-fold increase in risk of follicular lymphoma associated with ever exposure to leather dust [95% confidence interval (CI) 1.01-4.20]. After excluding subjects who ever worked in a farm or had ever been exposed to solvents, risk of B-cell lymphoma was elevated in relation to ever exposure to leather dust [odd ratio (OR) 2.2, 95% CI 1.00-4.78], but it was not supported by increasing trends with the exposure metrics. Risk of Hodgkin lymphoma was elevated (OR 2.0, 95% CI 0.95-4.30) for exposure to textile dust, with consistent upward trends by cumulative exposure and three independent exposure metrics combined (P=0.023, and P=0.0068, respectively). Conclusions Future, larger studies might provide further insights into the nature of the association we observed between exposure to textile dust and risk of Hodgkin lymphoma. ER -
COCCO, P., G. SATTA, F. MELONI, I. PILIA, F. AHMED, N. BECKER, D. CASABONNE, S. DE SANJOSÉ, Lenka FORETOVÁ, M. MAYNADIÉ, A. NIETERS, A. STAINES, A. T'MANNETJE, M. ZUCCA, M. G. ENNAS, M. CAMPAGNA, S. DE MATTEIS a Y. BENAVENTE. Occupational exposure to organic dust and risk of lymphoma subtypes in the EPILYMPH case-control study. \textit{SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT \&{} HEALTH}. HELSINKI: SCANDINAVIAN JOURNAL WORK ENVIRONMENT \&{} HEALTH, 2021, roč.~47, č.~1, s.~42-51. ISSN~0355-3140. Dostupné z: https://dx.doi.org/10.5271/sjweh.3925.
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